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91.
92.
Yoshiaki Katada Mayumi Yasumoto Chikako Ishii Hiroshi Tanaka Kazuya Nakamoto Isamu Ohashi Miwako Nozaki 《European radiology》2010,20(9):2241-2247
Objective
To evaluate the additional value of inversion recovery (IR) single-shot turbo spin-echo (SSTSE) imaging with sensitivity encoding (SENSE) using the inversion time (TI) value of hepatic haemangioma as a supplement to conventional T2-weighted turbo spin-echo (TSE) imaging for the discrimination of hepatic haemangiomas and cysts.Methods
A total of 134 lesions (77 hepatic haemangiomas, 57 hepatic cysts) in 59 patients were evaluated. Three readers evaluated these images and used a five-point scale to evaluate the lesion status. A receiver operating characteristic (ROC) analysis and 2?×?2 table analysis were used.Results
The ROC analysis for all the readers and all the cases revealed a significantly higher area under the curve (AUC) for the combination of moderately and heavily T2-weighted TSE with IR-SSTSE images (0.945) than for moderately and heavily T2-weighted TSE images alone (0.894) (P?<?0.001). For the combination of T2-weighted TSE with IR-SSTSE versus T2-weighted TSE alone, the 2?×?2 table analysis revealed a higher true-positive rate; this difference was statistically significant (P?<?0.0001).Conclusion
The introduction of IR-SSTSE with SENSE sequences significantly improves the diagnostic accuracy of the differentiation of hepatic haemangioma and cysts while increasing the time required for routine abdominal imaging by only 20 s. 相似文献93.
Osamu Dohi Nobuaki Yagi Atsushi Majima Yusuke Horii Tomoko Kitaichi Yuriko Onozawa Kentaro Suzuki Akira Tomie Reiko Kimura-Tsuchiya Toshifumi Tsuji Nobuhisa Yamada Nobukatsu Bito Tetsuya Okayama Naohisa Yoshida Kazuhiro Kamada Kazuhiro Katada Kazuhiko Uchiyama Takeshi Ishikawa Tomohisa Takagi Osamu Handa Hideyuki Konishi Yuji Naito Akio Yanagisawa Yoshito Itoh 《Gastric cancer》2017,20(2):297-303
Background
Blue laser imaging (BLI) is a new image-enhanced endoscopy technique that utilizes a laser light source developed for narrow-band light observation. The aim of this study was to evaluate the usefulness of BLI for the diagnosis of early gastric cancer.Methods
This single center prospective study analyzed 530 patients. The patients were examined with both conventional endoscopy with white-light imaging (C-WLI) and magnifying endoscopy with BLI (M-BLI) at Kyoto Prefectural University of Medicine between November 2012 and March 2015. The diagnostic criteria for gastric cancer using M-BLI included an irregular microvascular pattern and/or irregular microsurface pattern, with a demarcation line according to the vessel plus surface classification system. Biopsies of the lesions were taken after C-WLI and M-BLI observation. The primary end point of this study was to compare the diagnostic performance between C-WLI and M-BLI.Results
We analyzed 127 detected lesions (32 cancers and 95 non-cancers). The accuracy, sensitivity, and specificity of M-BLI diagnoses were 92.1, 93.8, and 91.6 %, respectively. On the other hand, the accuracy, sensitivity, and specificity of C-WLI diagnoses were 71.7, 46.9, and 80.0 %, respectively.Conclusions
M-BLI had improved diagnostic performance for early gastric cancer compared with C-WLI. These results suggested that the diagnostic effectiveness of M-BLI is similar to that of magnifying endoscopy with narrow-band imaging (M-NBI).94.
Yuki Kondo Chikatoshi Katada Satoshi Tanabe Takuya Wada Kenji Ishido Takafumi Yano Natsuko Kawanishi Yasuaki Furue Sakiko Yamane Mizuto Suzuki Akinori Watanabe Mizutomo Azuma Hiromitsu Moriya Keishi Yamashita Wasaburo Koizumi Akira Yokoyama 《Esophagus》2017,14(3):235-240
Background
This study was designed to validate a health-risk appraisal (HRA) model for identifying Japanese men in specialized hospitals who were at high risk for esophageal cancer on the basis of their past and present facial flushing reactions after drinking alcohol, drinking and smoking status, and intake of vegetables and fruit.Methods
We prospectively studied men 50 years or older with no history of head and neck cancer or esophageal cancer who presented at Kitasato University Hospital to undergo endoscopic examination from January 2011 to March 2013. The subjects responded to an HRA questionnaire before examination.Results
Among the 164 patients enrolled, 157 were eligible for analysis. The median HRA score was 3 in patients aged 70–90 years and 6 in those aged 50 to 69 years. Early esophageal cancer was diagnosed on endoscopic examination in 3 subjects (1.9%, 3/157). Among 70 patients 70–90 years of age, 18 (25.7%, 18/70) had an HRA score of 7 or higher, and early esophageal cancer was detected in 2 (11.1%, 2/18) of these patients. Early esophageal cancer was not detected in 87 patients 50–69 years of age. Early esophageal cancer was detected in a 70-year-old patient with an HRA score of 2 who had no history of drinking alcohol or smoking.Conclusions
Our results suggest that an HRA questionnaire is useful for identifying persons 70 years or older who are at high risk for alcohol-related esophageal cancer in specialized hospitals.95.
96.
Kawamura T Ishiguchi T Shibamoto Y Ogino H Ishihara S Yamada T Katada K Suzuki K Suzuki H Mimura M 《Radiation Medicine》2006,24(1):9-16
Purpose We analyzed the therapeutic results and prognostic factors of 46 primary central nervous system lymphoma (PCNSL) patients
who were treated at twelve institutions in the Tokai district of Japan between 1995 and 1999. We compared the results with
those of a Japanese nationwide survey performed in the past.
Materials and Methods We sent each institution a questionnaire about the state of patients' disease, pathological type, method and doses of radiotherapy,
regimen and intensity of chemotherapy, and patients' prognoses. The range of patients' ages was 33 to 93 years (median, 61
years). Thirty-one were men and 15 were women. The most prevalent histology was diffuse large B cell type (33 patients). We
used the Kaplan-Meier method to calculate the survival rate and Cox's proportional hazards model to analyze the prognostic
factors.
Results The five-year cumulative survival rate was 25%, and the median survival time was 22.7 months. The five-year disease-free survival
rate was 23%. In monovariate analysis, patients who were both younger than 60 years old and had a WHO performance status (PS)
score equal to or less than 2 showed a better survival rate. Furthermore, the patients receiving systemic chemotherapy showed
a significantly better local control rate. In addition, patients who received systemic chemotherapy achieved a higher complete
remission rate than those not receiving it. However, no factors that significantly influenced survival rate were identified
in multivariate analysis.
Conclusion We demonstrated that the therapeutic outcome of PCNSL patients has recently improved. In particular, patients with good PS
showed better local control than those with poor PS. However, we could not identify any significant prognostic factors in
PCNSL patients. 相似文献
97.
The present study investigated the effects of two orthodontic appliances on changes in the cephalometric reference planes using the three-dimensional finite element method. We simulated the use of a headgear and an orthopedic facial mask, two devices for the application of orthodontic force to the jaw. Using a finite element model of the skull, orthodontic force was applied to the maxillary first molar in a posterior or anterior direction. Changes in the maxilla, mandible and cephalometric reference planes were ascertained by the three-dimensional finite element method. The results showed that posterior force caused a slight posterior displacement and clockwise rotation of the reference planes, while anterior force caused anterior displacement and counterclockwise rotation. Since the maxilla was displaced and rotated in the same direction, the degrees of cephalometric displacement and rotation of the maxilla were smaller than the actual values. 相似文献
98.
Katada T Tsuchimochi M Oda T Sasaki Y Toyama M Katagiri M 《Odontology / the Society of the Nippon Dental University》2004,92(1):77-80
Nodular fasciitis (NF) is a benign reactive lesion of the soft tissues related to the fascia and characterized by fibroblastic proliferation. The most common site is the upper extremities (46%), followed by the head and neck region (20%). In the orofacial region, the lesion typically develops within the subcutaneous structures overlying the angle and inferior border of the mandible and the zygoma. Magnetic resonance imaging (MRI) findings of NF in the orofacial region are almost unreported in the literature. In the present case report, we describe MRI findings of mental NF in a 19-year-old woman. MRI revealed a well-defined, round soft-tissue mass lying on the mentum. On T1-weighted MRI, the lesion was isointense to skeletal muscle; it was hyperintense to skeletal muscle on T2-weighted MRI, and was enhanced by Gd-diethylenetriamine pentaacetic acid (DTPA). Histologic examination revealed abundant myxoid degeneration dispersed in the lesion. The T2-weighted higher heterogeneous signal intensity was likely due to abundant myxoid degeneration or the cellular component of the lesion. A strong bright signal intensity belt appeared in the periphery of the lesion on Gd-DTPA enhancement. This rim enhancement appearred to represent small arterioles and venules that were visible in the peripheral area on histologic examination. 相似文献
99.
c-Jun NH(2)-terminal kinase (JNK), also known as stress-activated protein kinase (SAPK), is activated primarily by inflammatory cytokines and environmental stresses including toxic metal exposure. To reveal the upstream kinase responsible for JNK activation by toxic metals, the phosphorylation status and the activity of JNK were examined in mouse embryonic stem (ES) cells lacking MKK4 or MKK7 following exposure to CdCl(2) or HgCl(2). Treatment with CdCl(2) or HgCl(2) induced the phosphorylation of JNK in a dose- and time-dependent manner in wild-type ES cells. In both mkk4(-/-) and mkk7(-/-) ES cells, CdCl(2)- or HgCl(2)-induced phosphorylation and activation of JNK were suppressed significantly. However, in mkk7(-/-) ES cells treated with CdCl(2) and HgCl(2), JNK activation was not abolished (suppressed by 56% and 78%, respectively). These findings suggest that the full activation of JNK by toxic metal exposure requires both MKK4 and MKK7, and these upstream kinases might contribute differentially in JNK activation between mouse ES cells exposed to CdCl(2) and HgCl(2). 相似文献
100.
Katada Y Kishino M Ishihara K Takeguchi T Shibuya H 《Acta radiologica (Stockholm, Sweden : 1987)》2008,49(9):987-990
The arterial supply of the gallbladder usually arises from the right hepatic artery. Other origins include the left, proper, and common hepatic arteries. We report cases of the cystic artery arising from the superior mesenteric artery and arising from the dorsal pancreatic artery originating in turn from the superior mesenteric artery, as demonstrated by angiography and computed tomography. 相似文献