全文获取类型
收费全文 | 1018篇 |
免费 | 66篇 |
国内免费 | 22篇 |
专业分类
耳鼻咽喉 | 3篇 |
儿科学 | 46篇 |
妇产科学 | 23篇 |
基础医学 | 92篇 |
口腔科学 | 12篇 |
临床医学 | 127篇 |
内科学 | 200篇 |
皮肤病学 | 2篇 |
神经病学 | 26篇 |
特种医学 | 314篇 |
外科学 | 42篇 |
综合类 | 21篇 |
一般理论 | 2篇 |
预防医学 | 37篇 |
眼科学 | 3篇 |
药学 | 134篇 |
中国医学 | 1篇 |
肿瘤学 | 21篇 |
出版年
2022年 | 3篇 |
2021年 | 12篇 |
2019年 | 6篇 |
2018年 | 7篇 |
2017年 | 2篇 |
2016年 | 4篇 |
2015年 | 17篇 |
2014年 | 11篇 |
2013年 | 22篇 |
2012年 | 23篇 |
2011年 | 31篇 |
2010年 | 23篇 |
2009年 | 26篇 |
2008年 | 23篇 |
2007年 | 32篇 |
2006年 | 21篇 |
2005年 | 20篇 |
2004年 | 17篇 |
2003年 | 17篇 |
2002年 | 15篇 |
2001年 | 18篇 |
2000年 | 15篇 |
1999年 | 15篇 |
1998年 | 52篇 |
1997年 | 46篇 |
1996年 | 57篇 |
1995年 | 44篇 |
1994年 | 34篇 |
1993年 | 41篇 |
1992年 | 13篇 |
1991年 | 17篇 |
1990年 | 18篇 |
1989年 | 41篇 |
1988年 | 41篇 |
1987年 | 31篇 |
1986年 | 28篇 |
1985年 | 41篇 |
1984年 | 27篇 |
1983年 | 28篇 |
1982年 | 28篇 |
1981年 | 25篇 |
1980年 | 15篇 |
1979年 | 7篇 |
1978年 | 9篇 |
1977年 | 30篇 |
1976年 | 22篇 |
1975年 | 19篇 |
1973年 | 4篇 |
1969年 | 2篇 |
1945年 | 1篇 |
排序方式: 共有1106条查询结果,搜索用时 406 毫秒
101.
102.
103.
104.
Diller AJ Rocha A Cardon AL Valles R Wellman PJ Nation JR 《Pharmacology, biochemistry, and behavior》2007,88(2):165-170
Conditioned place preference (CPP), a commonly used model for studying the role of contextual cues in drug reward and drug seeking, was employed to explore possible behavioral interactions between (+/-)3,4-methylenedioxymethamphetamine (MDMA; "ecstasy") and cocaine. On each of four occasions, adult male rats received one of three doses of MDMA (0 mg/kg, 5 mg/kg, 10 mg/kg; administered subcutaneously [s.c.]) combined with one of three doses of cocaine (0 mg/kg, 2.5 mg/kg, 5 mg/kg; administered intraperitoneally [i.p.]), and were then tested in a CPP paradigm. The results showed MDMA-induced CPP at a unit dose of 5 mg/kg, but at the 10 mg/kg dose there was a return to baseline (control) performance levels. For cocaine alone, CPP increased in a linear fashion as the drug dose was increased. Concurrent administration resulted in antagonism of each drug, but there was evidence that this pattern was reversible at higher doses of the respective drugs. These data are instructive insofar as they suggest that the behavioral and neurochemical effects of MDMA and cocaine presented in isolation are dramatically altered when the two drugs are presented in combination. 相似文献
105.
Altman AD Nelson G Nation J Chu P Ghatage P 《Journal d'obstetrique et gynecologie du Canada》2011,33(10):1031-1037
Vacuum assisted closure and negative pressure (NP) dressings are innovative forms of wound management used in multiple fields of medicine, including surgery. We review here the current literature in this area relevant for the gynaecologist. Negative pressure dressings increase blood flow to the wound, decrease bacterial counts, decrease tension on wound edges, and increase the formation of granulation tissue. Until recently, use of NP dressings has been contraindicated in wounds that have been previously radiated or that have necrotic tissue, an infection, an open fistula, an underlying malignancy, or an exposed blood vessel. In this review, we discuss the use of negative pressure for the treatment of abdominal wounds, including those associated with dehiscence, fistula, and prior radiation. We also discuss the use of NP dressings in gynaecologic oncology, including the vulvar and perineal areas. Finally, we outline the basics of applying NP dressings, and discuss pressure settings, "foam counts," debridement, and interface dressings to optimize the benefits of vacuum dressings. When used in the appropriate setting, NP dressing is a unique and important modality of treatment in gynaecology. 相似文献
106.
107.
RL Broadhead AS Muula 《Malawi medical journal : the journal of Medical Association of Malawi》2001,13(3):6-10
Ten years have now passed since the College of Medicine of the University of Malawi was opened. The College''s Curriculum is firmly based on community needs. We describe the genesis and implementation of the curriculum of the College of Medicine and how it has persisted over the past ten years. The challenges that have so far been met are outlined. 相似文献
108.
T Vesikari J Joensuu M Baer H Käyhty R-M Ölander H Sormunen A Miettinen RL Ward T Guillot 《Acta paediatrica (Oslo, Norway : 1992)》1999,88(5):513-520
To investigate the incorporation of oral rhesus-human reassortant rotavirus tetravalent (RRV-TV) vaccine into a routine immunization programme, RRV-TV or oral placebo was coadministered with a pentavalent diphtheria-tetanus-whole-cell pertussis-Haemophilus influenzae b (Hib)-inactivated polio vaccine and hepatitis B vaccine following a 3-4-5-mo schedule in a double-blind trial involving 249 infants. Seroconversion rates after 3 doses of rotavirus vaccine were 80% for rotavirus immunoglobulin A (IgA) and 93% for RRV neutralizing antibodies. Rotavirus vaccine did not interfere with the immune responses to diphtheria, tetanus, pertussis, Hib, poliovirus 1, 2 and 3, or hepatitis B. Following the first, second and third doses of vaccine, fever >38 degrees C on the day of vaccination was seen in 31%, 24% and 24%, respectively, with no difference between RRV-TV- and placebo-vaccinated children. This fever was presumably due to the whole-cell pertussis vaccine. Those vaccinees who received concomitant RRV-TV vaccine had another peak of fever around d 4 after the first dose, when 25% of them had fever >38 degrees C and 3% >39 degrees C. It is concluded that RRV-TV rotavirus vaccine can be given concurrently with other childhood immunizations following a 3-4-5-mo vaccination schedule. However, febrile reactions to RRV-TV rotavirus vaccine are common when the first dose is given at the age of 3 mo. 相似文献
109.
Sickle cell anemia patients have low erythropoietin levels for their degree of anemia 总被引:3,自引:1,他引:2
We have studied serum immunoreactive erythropoietin (SIE) levels in 28 patients with sickle cell anemia (SCA) without renal insufficiency and in 17 patients with nonhemoglobinopathy anemias of comparable severity using a sensitive radioimmunoassay procedure. An exponential relationship between SIE level and degree of anemia was noted in all patients. However, in nonhemoglobinopathy anemia, a sharp rise in the SIE level occurred as hemoglobin (Hb) levels fell below about 12 g/dL, whereas in sickle cell patients the increase was not marked until hemoglobin fell to about 9 g/dL. The response was more blunted in older SCA patients than in younger ones. A linear regression model relating SIE level to Hb level, presence/absence of SCA, and age explained 63% of the variation in SIE. We conclude that the serum erythropoietin levels in SCA increased at a lower hemoglobin concentration and are of a lower magnitude than that of the other anemias. 相似文献
110.
Splenic lymphangiomatosis in children 总被引:14,自引:0,他引:14