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21.
Surinder K. Singhal Naresh K. Panda S. B. S. Mann Ashim Dass 《Indian journal of otolaryngology and head and neck surgery》1997,49(3):265-268
Basaloid squamous cell carcinoma is a rare variant of squamous cell carcinoma, Larynx has been an uncommon site of this tumour
which is said to have aggressive biological behaviour with high incidence of cervical and distant metastasis along with second
primary. Two cases of laryngeal basaloid squamous cell carcinoma are reported with relevant review of literature. The submucosal
spread of tumour is highlighted alongwith role of preoperative radio therapy. 相似文献
22.
23.
Jaimanti Naresh K. Panda Suresh Sharma Ashok K. Gupta S. B. S. Mann 《Indian journal of otolaryngology and head and neck surgery》2004,56(2):99-104
Conclusion Patients with stage I and II tumors had the best results with radical radiotherapy alone 5 years survival for patients with
stage I and stage II tumors was 90-95% and 75-85% respectively Patients with advanced stage III & IV disease were treated
Unoperable stage IV cancer patients had poor outcome and received only palliative treatment 相似文献
24.
Arunaloke Chakrabarti Ashim Das Naresh K Panda 《Indian journal of otolaryngology and head and neck surgery》2004,56(4):251-258
The incidence of fungal rhinosinusitis has increased to such extent in recent years that fungal infection should be considered
in all patients with chronic rhino sinusitis. In India though the disease was reported earlier only from northern regions
of this country, nowadays the disease is increasingly diagnosed from other parts as well. The disease has been categorized
with possible five types: acute necrothing (fulminant), chronic invasive, chronic granulomatous invasive, fungal hall (sinus
mycetoma), allergic. The first three types are tissue-invasive and the last two are non-invasive fungal rhinosinusitis. However,
the categorization is still controversial and open to discussion. Chronic fungal rhinosinusitis can occur in otherwise healthy
host and Aspergillus flavus is the common etiological agent in Indian scenario. The pathophys iologic mechanism of the disease
remains unclear. It may represent an allergic IgE response, a cell-mediated reaction, or a combination of two. Early diagnosis
may prevent multiple surgical procedures and lead to effective treatment. Histopathology and radio-imaging techniques help
to distinguish different types and delineate extension of disease process. Culture helps to identify the responsible etiological
agent. The presence or absence oj precipitating antibody correlates well with disease progression or recovery. The most immediate
need regarding management is to establish the respective roles of surgery and antifungal therapy. Non-invasive disease requires
surgical debridement and sinus ventilation only, though, additional oral or local corticosterold therapy may be beneficial
in allergie type. For invasive disease, the adjuvant medical therapy is recommended to prevent recurrence and further extension.
Itraconazole has been found as an effective drug in such situation. Patients with acute neerotizing type require radical surgery
and amphotericin B therapy. 相似文献
25.
Jaimanti Bakshi Naresh K. Panda Suresh C. Sharma Ashok Gupta S. B. S. Mann 《Indian journal of otolaryngology and head and neck surgery》2005,57(2):103-107
Carcinoma of larynx is a common disease in North Indian population. It is seen commonly in smokers and alcoholics. It poses a serious health problem due to its tendency to cause airway obstruction and to make the patient aphonic if total larynxgectomy is done for curing this cancer. We conducted a retrospective analysis in 690 cases of carcinoma larynx presenting to Nehru Hospital, Postgraduate Institute of Medical Education and Research, Chandigarh. Various aspects of this disease like predisposing factors, patterns of spread, histological types, various treatment modalities, their complications and response of this disease to these therapeutic options were studied in detail. 相似文献
26.
Naresh K. Panda Ekambar C. E. Reddy Rajiv J. Bapuraj 《Indian journal of otolaryngology and head and neck surgery》2005,57(2):150-152
Two cases of spontaneous cessation of cerebrospinal fluid (CSF) rhinorrhea following iohexol computerized tomographic (CT) cisternography are presented. This report contradicts the current thinking about conservative treatment in CSF rhinorrhea. We propose that iohexol CT cisternography may have a therapeutic role in the management of spontaneous CSF rhinorrhea. 相似文献
27.
Predictive Value of D‐Dimer Levels and Tissue Doppler Mitral Annular Systolic Velocity for Detection of Left Atrial Appendage Thrombus in Patients with Mitral Stenosis in Sinus Rhythm
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28.
Diagnostic utility of testosterone priming prior to dynamic tests to differentiate constitutional delay in puberty from isolated hypogonadotropic hypogonadism
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29.
Naresh Kasoju Ramesh R. Bhonde Utpal Bora 《Journal of tissue engineering and regenerative medicine》2009,3(7):539-552
The quest for novel materials as scaffolds with suitable micro‐architecture for supporting tissue neogenesis in tissue engineering and regenerative medicine (TERM) is continuing. In this paper we report an Antheraea assama silk‐based non‐woven fibroin scaffold for applications in TERM. The novel three‐dimensional scaffold is highly interconnected and porous, with a pore size of 150 µm, porosity of 90% and water uptake capacity of 85%. FTIR revealed a typical β‐sheet structure of fibroin. The scaffold has thermal and mechanical properties superior to those of Bombyx mori, as revealed by DSC, TGA and tensile tests. The scaffold exhibited satisfactory blood compatibility, as determined by thrombogenicity, haemolysis, platelet/leukocyte count, platelet adhesion and protein adsorption studies. The scaffold was found to be cytocompatible with human cell lines A549, KB, HepG2 and HeLa for a period of up to 4 weeks. SEM analysis revealed excellent attachment, spreading and migration of cells in the scaffold. MTT assay was performed to estimate the viability and growth of cells in the matrix. Quantification of collagen in cell–scaffold constructs was done by picro‐Sirius red assay. Ex ovo chorioallantoic membrane assay and nitric oxide estimations in spent culture medium showed the scaffold's ability to promote angiogenesis. Finally, the biodegradability of the scaffold was determined by the weight loss observed upon treatment with trypsin over a period of 4 weeks. The results reveal that the fibroin from A. assama is a promising candidate as a biocompatible, biomimetic and biodegradable biomaterial of natural origin for applications in TERM. Copyright © 2009 John Wiley & Sons, Ltd. 相似文献
30.
Minimally invasive mitral valve surgery 总被引:1,自引:0,他引:1
Mishra Y Sharma M Bapna R Malhotra R Mehta Y Sharma KK Shrivastava S Trehan N 《Indian heart journal》2002,54(3):279-283
BACKGROUND: To reduce surgical trauma and the drawbacks associated with sternotomy, we performed robotically controlled, video-assisted mitral valve surgery, using either the port-access or the transthoracic clamp technique. METHODS AND RESULTS: Between September 1997 and September 2000, 221 patients (78 males, 143 females) underwent mitral valve surgery through a small right minithoracotomy using the port-access endovascular cardiopulmonary bypass system. Mitral valve exposure was facilitated with an endoscope attached to a voice-controlled robotic arm (AESOP 3000) allowing stabilization and voice-activated camera positioning. Twenty-six patients underwent mitral valve repair and 195 had valve replacement. In 197 patients, mitral valve surgery was the primary operation, while 24 were redo cases. Skin-to-skin mean operating time was 3.5 +/- 1.2 hours and aortic cross-clamp time was 58 +/- 16 min, mean intensive care unit stay was 22 +/- 7 hours and hospital stay 6.4 +/- 1.2 days. There was no re-exploration for bleeding. There was no late death or re-operation on mean follow-up of 16.4 +/- 12.2 months. Patients showed improvement in their NYHA functional class from 2.6 +/- 0.5 to 1.4 +/- 0.8 postoperatively. Outcomes were compared with those of our previous 220 patients who underwent mitral valve surgery with the median sternotomy approach. CONCLUSIONS: The use of video and robotic assistance in port-access mitral valve surgery not only minimizes the length of the incision, but also gives full visualization of the entire mitral valve apparatus. This approach provides comparable results with the sternotomy approach, as well as marked advantages of reduced intensive care unit stay. ,ower blood transfusion requirement, better cosmesis and earlier hospital discharge. 相似文献