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51.
G. Vacca E. Marano V. Brescia Morra R. Lanzillo M. De Vito E. Parente G. Orefice 《Neurological sciences》2007,28(3):133-135
The prevalence of primary headache (PH) in a multiple sclerosis (MS) sample vs. control healthy subjects was investigated at a neurological clinic in 2004–2005: 122 of 238 (51%) MS patients and 57 of
238 (23%) controls proved to be affected by headache. The groups did not differ for the rates of PH types. Headache types
of MS patients were comparable to those of PH patients that were observed at the same institute in a case-control comparison.
First symptoms of headache preceded those of MS in two thirds of cases. Headache features did not significantly change after
MS onset. Comorbidity of MS and PH could be explained by some common clinical and biological traits. 相似文献
52.
Volker Heinemann 《Breast cancer research and treatment》2003,81(1):43-48
Single-agent chemotherapy of metastatic breast cancer is the treatment of choice in patients with slow tumor progression and asymptomatic disease. In this patient group, the choice of drugs is based more on good tolerability than on efficacy. By contrast, symptomatic or rapidly progressing disease requires the use of highly active regimens where more weight is put on reliable antitumor activity. While anthraycline-based combination regimens have set the standard of effective treatment, the addition of docetaxel (and to a lesser extent paclitaxel) has improved tumor response, but failed to induce a consistent prolongation of survival. Based on retrospective analyses, it is hypothesised that the combined use of anthracyclines and taxanes in first-line therapy may be most beneficial in defined subgroups: after adjuvant chemotherapy, in patients with HER-2 gene amplification, possibly also in patients with rapidly progressing visceral disease. 相似文献
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Ohne Zusammenfassung 相似文献
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Antegrade interlocking nailing of humeral shaft fractures 总被引:5,自引:0,他引:5
George Petsatodes Dimitrios Karataglis Pericles Papadopoulos John Christoforides John Gigis John Pournaras 《Journal of orthopaedic science》2004,9(3):247-252
The results of 39 humeral shaft fractures (37 patients) treated with antegrade locked nailing using a Russell–Taylor nail were reviewed. There were 30 acute fractures, 6 fractures malaligned in a hanging cast or brace, and 3 pathological fractures. Patient age ranged from 26 to 80 years (average, 59.7 years) and average follow-up was 25.7 months (range, 6–48 months). Fracture union was achieved in 92.3% of our cases, while shoulder function was excellent or good in 87.2% of cases. Antegrade locked nailing offers a dependable solution for the treatment of humeral shaft fractures, especially in polytrauma patients and cases of segmental or pathological fractures. Far less satisfactory results were obtained in comminuted fractures of the proximal third in the humerus, especially in osteoporotic patients, and we therefore advocate caution with the use of intramedullary nailing in this type of fracture. Certain technical aspects such as avoiding nailing the fracture in distraction, properly countersinking the tip of the nail, and achieving adequate fixation stability have been found to be of paramount importance to reduce the incidence of delayed union/non-union rate and to obtain better functional results from the shoulder joint. 相似文献
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Daniel M. Herron 《Journal of gastrointestinal surgery》2004,8(4):406-407
Conclusion In the year 2003 there is no “one best bariatric operation” for every severely obese patient. The choice of operation must
be tailored to each individual patient’s needs and wishes. For the superobese patient, the patient diagnosed with intestinal
metaplasia of the stomach, and for those patients who do not wish to undergo the severe dietary restrictions imposed by the
RNY-GB, the BPD-DS is a valuable surgical option. 相似文献
59.
Melinda S. Lantz 《Current Psychosis and Therapeutics Reports》2004,2(1):7-12
Depressive symptoms in older adults are common, but the minority of elderly meet criteria for major depressive disorder. This
has led to confusion regarding the recognition of diagnosis, approach to treatment, and monitoring of outcomes in this needy
population. Few depressed older adults are willing to seek treatment from psychiatrists or mental health specialists. Treatment
approaches to the depressive spectrum of disorders in late life, which encompasses major and minor depressive disorder, dysthymic
disorder, and mood disorders related to medical conditions, must include evidence-based algorithms that can be delivered in
a variety of health care settings. Several recent multisite trials have advanced the use of collaborative care models and
the systematic stepwise approach to the treatment of depression and anxiety states in older adults. This offers the ability
to provide effective treatment of depression for older adults, consistent with current guidelines, in primary care and specialized
health care settings. 相似文献
60.