全文获取类型
收费全文 | 823479篇 |
免费 | 55230篇 |
国内免费 | 1557篇 |
专业分类
耳鼻咽喉 | 11070篇 |
儿科学 | 26925篇 |
妇产科学 | 20150篇 |
基础医学 | 126410篇 |
口腔科学 | 24084篇 |
临床医学 | 70952篇 |
内科学 | 163740篇 |
皮肤病学 | 20002篇 |
神经病学 | 58787篇 |
特种医学 | 28458篇 |
外国民族医学 | 77篇 |
外科学 | 119323篇 |
综合类 | 15450篇 |
现状与发展 | 2篇 |
一般理论 | 195篇 |
预防医学 | 63009篇 |
眼科学 | 19009篇 |
药学 | 62038篇 |
3篇 | |
中国医学 | 2914篇 |
肿瘤学 | 47668篇 |
出版年
2021年 | 7824篇 |
2019年 | 8119篇 |
2018年 | 12519篇 |
2017年 | 8827篇 |
2016年 | 9325篇 |
2015年 | 10349篇 |
2014年 | 13423篇 |
2013年 | 20236篇 |
2012年 | 29127篇 |
2011年 | 30702篇 |
2010年 | 17297篇 |
2009年 | 15110篇 |
2008年 | 27360篇 |
2007年 | 29406篇 |
2006年 | 29219篇 |
2005年 | 27706篇 |
2004年 | 26398篇 |
2003年 | 24944篇 |
2002年 | 24103篇 |
2001年 | 39799篇 |
2000年 | 40979篇 |
1999年 | 33395篇 |
1998年 | 8344篇 |
1997年 | 6936篇 |
1996年 | 7252篇 |
1995年 | 6846篇 |
1994年 | 6259篇 |
1992年 | 24143篇 |
1991年 | 23916篇 |
1990年 | 23181篇 |
1989年 | 22784篇 |
1988年 | 20637篇 |
1987年 | 19994篇 |
1986年 | 19052篇 |
1985年 | 17796篇 |
1984年 | 13065篇 |
1983年 | 11024篇 |
1982年 | 6053篇 |
1979年 | 11832篇 |
1978年 | 8319篇 |
1977年 | 7018篇 |
1976年 | 6788篇 |
1975年 | 7521篇 |
1974年 | 8791篇 |
1973年 | 8474篇 |
1972年 | 7932篇 |
1971年 | 7424篇 |
1970年 | 7161篇 |
1969年 | 6586篇 |
1968年 | 6039篇 |
排序方式: 共有10000条查询结果,搜索用时 759 毫秒
21.
Novozhilov A. V. Mindukshev I. V. Korf E. A. Krivchenko A. I. Goncharov N. V. 《Bulletin of experimental biology and medicine》2020,168(4):444-448
Bulletin of Experimental Biology and Medicine - Ammonium, an end-product of catabolism, in low doses can promote adaptation of metabolic pathways in erythrocytes under conditions of extreme... 相似文献
22.
23.
Martin R. Späth Malte P. Bartram Nicolàs Palacio-Escat K. Johanna R. Hoyer Cedric Debes Fatih Demir Christina B. Schroeter Amrei M. Mandel Franziska Grundmann Giuliano Ciarimboli Andreas Beyer Jayachandran N. Kizhakkedathu Susanne Brodesser Heike Göbel Jan U. Becker Thomas Benzing Bernhard Schermer Martin Höhne Markus M. Rinschen 《Kidney international》2019,95(2):333-349
24.
Ángel Becerra Héctor Trujillo Lucía Valencia Aurelio Rodríguez‐Pérez 《Brazilian Journal of Anesthesiology》2019,69(2):200-203
Background and objectives
A prompt and effective management of trauma patient is necessary. The aim of this case report is to highlight the importance of intraoperative echocardiography as a useful tool in patients suffering from refractory hemodynamic instability no otherwise explained.Case report
A 41 year‐old woman suffered a car accident. At the emergency department, no abnormalities were found in ECG or chest X‐ray. Abdominal ultrasound revealed the presence of abdominal free liquid and the patient was submitted to urgent exploratory laparotomy. Nevertheless, she persisted suffering arterial hypotension and metabolic acidosis. Looking for the reason of her hemodynamic instability, intraoperative transthoracic echocardiography was performed, finding out the presence of pericardial effusion. Once the cardiac surgeon extracted pericardial clots, patient's situation improved clinically and analytically.Conclusion
Every anesthesiologist should be able to use the intraoperative echocardiography as an effective tool in order to establish the appropriate measures to promote the survival of patients suffering severe trauma. 相似文献25.
Ali Mobasheri Csaba Matta Ilona Uzielienè Emma Budd Pablo Martín-Vasallo Eiva Bernotiene 《Joint, bone, spine : revue du rhumatisme》2019,86(1):29-35
Chondrocytes are the main cells in the extracellular matrix (ECM) of articular cartilage and possess a highly differentiated phenotype that is the hallmark of the unique physiological functions of this specialised load-bearing connective tissue. The plasma membrane of articular chondrocytes contains a rich and diverse complement of membrane proteins, known as the membranome, which defines the cell surface phenotype of the cells. The membranome is a key target of pharmacological agents and is important for chondrocyte function. It includes channels, transporters, enzymes, receptors, and anchors for intracellular, cytoskeletal and ECM proteins and other macromolecular complexes. The chondrocyte channelome is a sub-compartment of the membranome and includes a complete set of ion channels and porins expressed in these cells. Many of these are multi-functional proteins with “moonlighting” roles, serving as channels, receptors and signalling components of larger molecular assemblies. The aim of this review is to summarise our current knowledge of the fundamental aspects of the chondrocyte channelome, discuss its relevance to cartilage biology and highlight its possible role in the pathogenesis of osteoarthritis (OA). Excessive and inappropriate mechanical loads, an inflammatory micro-environment, alternative splicing of channel components or accumulation of basic calcium phosphate crystals can result in an altered chondrocyte channelome impairing its function. Alterations in Ca2+ signalling may lead to defective synthesis of ECM macromolecules and aggravated catabolic responses in chondrocytes, which is an important and relatively unexplored aspect of the complex and poorly understood mechanism of OA development. 相似文献
26.
27.
28.
B Maybury A Powell-Chandler N Kumar 《Annals of the Royal College of Surgeons of England》2015,97(3):e37-e38
We report two British cases of liver abscess, due to Klebsiella pneumoniae and associated with synchronous infection elsewhere, which required liver resection for definitive treatment. They illustrate the geographic spread of aggressive K pneumoniae liver infection and demonstrate the importance of early aggressive treatment. 相似文献
29.
Autoimmune comorbid diseases associated with lichen planus: a nationwide case–control study
下载免费PDF全文
![点击此处可从《Journal of the European Academy of Dermatology and Venereology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
30.
M.T. Leccia N. Auffret F. Poli J.‐P. Claudel S. Corvec B. Dreno 《Journal of the European Academy of Dermatology and Venereology》2015,29(8):1485-1492
Acne vulgaris (acne) is a chronic inflammatory disease of the sebaceous gland, characterized by follicular hyperkeratinization, excessive colonization by Propionibacterium acnes (P. acnes) as well as immune reactions and inflammation. Despite an armamentarium of topical treatments available including benzoyl peroxide, retinoids and azelaic acid, topical antibiotics in monotherapies, especially erythromycin and clindamycin, are still used in Europe to treat acne. This intensive use led to antimicrobial‐resistant P. acnes and staphylococci strains becoming one of the main health issues worldwide. This is an update on the current topical acne treatments available in Europe, their mechanism of action, their potential to induce antimicrobial resistance and their clinical efficacy and safety. 相似文献