全文获取类型
收费全文 | 862289篇 |
免费 | 56182篇 |
国内免费 | 1659篇 |
专业分类
耳鼻咽喉 | 11351篇 |
儿科学 | 27798篇 |
妇产科学 | 21271篇 |
基础医学 | 132908篇 |
口腔科学 | 25493篇 |
临床医学 | 72879篇 |
内科学 | 168887篇 |
皮肤病学 | 20421篇 |
神经病学 | 62101篇 |
特种医学 | 29522篇 |
外国民族医学 | 79篇 |
外科学 | 122604篇 |
综合类 | 15562篇 |
现状与发展 | 2篇 |
一般理论 | 186篇 |
预防医学 | 70633篇 |
眼科学 | 20457篇 |
药学 | 66112篇 |
3篇 | |
中国医学 | 3022篇 |
肿瘤学 | 48839篇 |
出版年
2021年 | 7893篇 |
2019年 | 8242篇 |
2018年 | 12668篇 |
2017年 | 9080篇 |
2016年 | 9779篇 |
2015年 | 10883篇 |
2014年 | 13985篇 |
2013年 | 21012篇 |
2012年 | 30246篇 |
2011年 | 31864篇 |
2010年 | 17806篇 |
2009年 | 15660篇 |
2008年 | 28402篇 |
2007年 | 30597篇 |
2006年 | 30550篇 |
2005年 | 28702篇 |
2004年 | 27641篇 |
2003年 | 26105篇 |
2002年 | 25280篇 |
2001年 | 40740篇 |
2000年 | 41856篇 |
1999年 | 34140篇 |
1998年 | 8550篇 |
1997年 | 7068篇 |
1996年 | 7383篇 |
1995年 | 6995篇 |
1994年 | 6400篇 |
1992年 | 25024篇 |
1991年 | 24786篇 |
1990年 | 24149篇 |
1989年 | 23656篇 |
1988年 | 21544篇 |
1987年 | 20830篇 |
1986年 | 19918篇 |
1985年 | 18662篇 |
1984年 | 13674篇 |
1983年 | 11582篇 |
1982年 | 6372篇 |
1979年 | 12657篇 |
1978年 | 8885篇 |
1977年 | 7571篇 |
1976年 | 7294篇 |
1975年 | 8099篇 |
1974年 | 9588篇 |
1973年 | 9263篇 |
1972年 | 8728篇 |
1971年 | 8166篇 |
1970年 | 7852篇 |
1969年 | 7345篇 |
1968年 | 6848篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
41.
42.
43.
44.
45.
Andres Eduardo Campuzano-García Bertha Torres-Alvarez Diana Hernández-Blanco 《Journal of cosmetic and laser therapy》2015,17(4):213-215
Hailey–Hailey disease (HHD), also known as benign familial pemphigus, is an autosomal dominant skin condition that affects the adhesion of epidermal keratinocytes. Although the initial manifestation of flaccid vesicles on erythematous or normal skin in flexure sites frequently goes unnoticed, large, macerated, exudative plaques of superficial erosions with crusting are observed at the time of diagnosis. There is no specific treatment for HHD, and most cases are symptomatically supported. However, infrared laser ablation has been somewhat helpful. We present a case successfully treated with fractional CO2 laser showing a long-term favourable outcome and no adverse effects. Thus, this modality could be an alternative to full ablation for this condition. 相似文献
46.
Alejandra Gordillo Hernández Eduardo Dominguez-Adame Lanuza Auxiliadora Cano Matias Rosario Perez Huertas Katherine Maria Gallardo Rodriguez Purificacion Gallinato Perez Fernando Oliva Mompean 《World journal of gastrointestinal surgery》2015,7(8):170-173
Gangliocytic paragangliomas are rare tumors that almost exclusively occur within the second portion of the duodenum. Although these tumors generally have a benign clinical course, they have the potential to recur or metastasize to regional lymph nodes. The case report presented here describes a 57-year-old female patient with melena, progressive asthenia, anemia, and a mass in the second-third portion of the duodenum that was treated by local excision. The patient was diagnosed with a friable bleeding tumor. The histologic analysis showed that the tumor was a 4 cm gangliocytic paraganglioma without a malignant cell pattern. In the absence of local invasion or distant metastasis, endoscopic resection represents a feasible, curative therapy. Although endoscopic polypectomy is currently considered the treatment of choice, it is not recommended if the size of the tumor is > 3 cm and/or there is active or recent bleeding. Patients diagnosed with a gangliocytic paraganglioma should be closely followed-up for possible local recurrence. 相似文献
47.
Primary cutaneous anaplastic large cell lymphomas with 6p25.3 rearrangement exhibit particular histological features
下载免费PDF全文
![点击此处可从《Histopathology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
48.
49.
A case of bullous pemphigoid associated with psoriasis vulgaris showing Hailey–Hailey disease‐like histopathological changes in regenerated epidermis without genomic mutation in ATP2C1 or ATP2A2 gene
下载免费PDF全文
![点击此处可从《Journal of the European Academy of Dermatology and Venereology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
50.
Context Withania somnifera (L.) Dunal is traditionally used for treating various ailments, but lacks scientific evaluation.Objective This study evaluates Withania somnifera (WS) for its effect on platelet activity and inflammatory enzymes.Materials and methods Aqueous and ethanolic (1:1) leaf extracts were subjected to in vitro indirect haemolytic activity using Naja naja venom, human platelet aggregation was quantified for lipid peroxidation using arachidonic acid (AA) as agonist and 5-lipoxygenase (5-LOX) levels were determined using standard spectrometric assays. Further, molecular docking was performed by the ligand fit method using molegro software package (Molegro ApS, Aarhus, Denmark).Results The study found that aqueous and ethanol extracts have very negligible effect (15%) with an IC50 value of 13.8?mg/mL on PLA2 from Naja naja venom. Further, extracts of WS also had very little effect (18%) with an IC50 value of 16.6?mg/mL on malondialdehyde (MDA) formation. However, a 65% inhibition of 5-LOX with an IC50 value of 0.92?mg/mL was observed in 1:1 ethanol extracts. The same was evident from SAR model with the active ingredient withaferin A binding predominantly on Phe 77, Tyr 98, Arg 99, Asp 164, Leu 168, Ser 382, Arg 395, Tyr 396 and Tyr 614 with an atomic contact energy value of??128.96 compared to standard phenidone (?103.61). Thus, the current study validates the application of WS for inflammatory diseases.Conclusion This study reveals the inhibitory potential of W. somnifera on inflammatory enzymes and platelet aggregation. Thus, WS can serve as a newer, safer and affordable medicine for inflammatory diseases. 相似文献