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21.
Marta Revilla‐Len Joshua Fountain Wenceslao Piedra‐Cascn Amirali Zandinejad Mutlu
zcan 《Journal of prosthodontics》2019,28(8):855-860
The present article describes the resin infiltration technique to address white spots lesions presented on anterior and premolar teeth of a young patient after orthodontic treatment and the digital workflow for planning a diastema closure on the maxillary anterior teeth using facial photographs, an intraoral scanner, a facially driven diagnostic waxing using a dental computer‐aided design (CAD) software, and 3‐piece additive manufactured (AM) clear silicone indices. The virtual design of the silicone indices was completed using an open‐source CAD software and included a flexible clear buccal piece, flexible clear lingual piece, and rigid clear custom tray. The unique 3‐piece index design allows a horizontal path of insertion, controlled uniform thickness of the indices, flexible and rigid material properties combination, accurate translation of the diagnostic waxing into the patient´s mouth, and digital storage of the designs. 相似文献
22.
23.
Possible hazardous effects of hydrofluoric acid and recommendations for treatment approach: a review
Hydrofluoric acid (HF) is commonly used for conditioning the glass ceramics either prior to cementation or for intraoral repair
in prosthetic and restorative dentistry. The present study offers a review of chemical properties of HF used, highlight the
possible hazardous effects of this agent, and to recommend the treatment approach for potential risks. Available published
information documented in PubMed, Medline, and Picarta literature databases was reviewed. Additional information was derived
from scientific reports, medical and chemical textbooks, handbooks, product information, manufacturers’ instructions, Internet
web sites of the HF manufacturers. No report was found on the incidence of the hazardous effects of HF in dentistry. Reports
from other fields presented incidences of acute and chronic symptoms in exposure to HF. While acute symptoms include skin
or nail burns, chronic ones involve systemic toxicity, eye injuries, inhalation and ingestion-related symptoms that can be
even fatal. HF can be harmful and particularly aggressive to soft tissues, but symptoms may not be apparent immediately after
exposure. The hazardous effects are not based on the pH value, but on the toxicity of HF. Potential hazards of HF known from
other applications than dentistry should be considered also in dental applications. Especially the clinicians, who often deal
with adhesive cementation or repair of glass ceramics, should take necessary precautions for possible hazards of HF. 相似文献
24.
Volkan Turp Deniz Sen Betul Tuncelli Mutlu ?zcan 《The journal of advanced prosthodontics》2013,5(3):226-233
PURPOSE
This study evaluated the adhesion of 10-MDP containing self-etch and self-adhesive resin cements to dentin with and without the use of etch-and-rinse technique.MATERIALS AND METHODS
Human third molars (N=180) were randomly divided into 6 groups (n=30 per group). Conventional (Panavia F2.0, Kuraray-PAN) and self-adhesive resin cements (Clearfil SA, Kuraray-CSA) were bonded to dentin surfaces either after application of 3-step etch-and-rinse (35% H3PO4 + ED Primer) or two-step self-etch adhesive resin (Clearfil SE Bond). Specimens were subjected to shear bond strength test using the universal testing machine (0.5 mm/min). The failure types were analyzed using a stereomicroscope and quality of hybrid layer was observed under a scanning electron microscope. The data (MPa) were analyzed using two-way ANOVA and Tukey''s tests (α=.05).RESULTS
Overall, PAN adhesive cement showed significantly higher mean bond strength (12.5 ± 2.3 - 14.1 ± 2.4 MPa) than CSA cement (9.3 ± 1.4 - 13.9 ± 1.9 MPa) (P<.001). Adhesive failures were more frequent in CSA cement groups when used in conjunction with two-step self-adhesive (68%) or no adhesive at all (66%). Hybrid layer quality was inferior in CSA compared to PAN cement in all conditions.CONCLUSION
In clinical situations where bonding to dentin substrate is crucial, both conventional and self-adhesive resin cements based on 10-MDP can benefit from etch-and-rinse technique to achieve better quality of adhesion in the early clinical period. 相似文献25.
Fatih Mehmet Korkmaz Bora Bagis Mutlu ?zcan Rukiye Durkan Sedanur Turgut Sabit Melih Ates 《The journal of advanced prosthodontics》2013,5(3):287-295
PURPOSE
This study investigated the effect of laser parameters and air-abrasion on the peel strength of silicon-based soft denture liner to different denture resins.MATERIALS AND METHODS
Specimens (N=180) were prepared out of three different denture base resins (Rodex, cross-linked denture base acrylic resin; Paladent, heat-cured acrylic resin; Deflex, Polyamide resin) (75 mm × 25 mm × 3 mm). A silicon-based soft denture liner (Molloplast B) was applied to the denture resins after the following conditioning methods: a) Air-abrasion (50 µm), b) Er,Cr:YSGG laser (Waterlase MD Turbo, Biolase Technology) at 2 W-20 Hz, c) Er,Cr:YSGG laser at 2 W-30 Hz, d) Er,Cr:YSGG laser at 3 W-20 Hz, e) Er,Cr:YSGG laser at 3 W-30 Hz. Non-conditioned group acted as the control group. Peel test was performed in a universal testing machine. Failure modes were evaluated visually. Data were analyzed using two-way ANOVA and Tukey''s test (α=.05).RESULTS
Denture liner tested showed increased peel strength after laser treatment with different parameters (3.9±0.4 - 5.58±0.6 MPa) compared to the control (3.64±0.5 - 4.58±0.5 MPa) and air-abraded groups (3.1±0.6 - 4.46±0.3 MPa), but the results were not statistically significant except for Paladent, with the pretreatment of Er,Cr:YSGG laser at 3 W-20 Hz. Polyamide resin after air-abrasion showed significantly lower peel strength than those of other groups (3.1±0.6 MPa).CONCLUSION
Heat-cured acrylic resin, PMMA, may benefit from Er,Cr:YSGG laser treatment at 3 W-20 Hz irradiation. Air-abrasion of polyamide resins should be avoided not to impair their peel bond strengths to silicon-based soft denture liners. 相似文献26.
27.
The purpose of this study was to evaluate the effect of different adhesive cements and thermocycling on the fracture resistance of IPS e.max Press posterior single crowns. Thirty-two sound maxillary molars were subjected to standardized preparation and received IPS e.max Press crowns. Another 16 molars were left unprepared to serve as controls (group 1). Panavia F 2.0 and Rely X Unicem luting cements were used to bond the fabricated crowns (n = 16 each) to their respective prepared teeth. Eight specimens from each of the three groups were selected randomly for further thermocycling (5,000 cycles). All specimens were then subjected to fracture resistance testing using anatomical metal attachments fixed to the upper portion of the universal testing machine (1 mm/min). Data were analyzed statistically using two-way analysis of variance and the Student t test (α = .05). Natural teeth presented significantly higher (1,043 and 1,279 N) fracture resistance than that of adhesively cemented ceramic crowns (907 to 986 N) before and after thermocyling, respectively (P < .05). Cement type did not significantly affect fracture resistance results (986 N and 974 N for Panavia F 2.0 and Rely X Unicem, respectively; P > .05). Thermocycled specimens showed lower fracture resistance than that of nonthermocycled ones (P < .05). Neither conventional adhesive cement nor self-etching adhesive cement affected the fracture resistance of IPS e.max crowns. Thermocycling decreased the fracture strength of the crowns in both cement groups. Natural teeth fractured at significantly higher loads than the ceramic crowns. 相似文献
28.
Tarik Artis A. Seda Artis Ergin Arslan Fatih Mutlu Abdurrahman Akay Kemal Deniz 《Journal of investigative surgery》2016,29(5):260-265
Objective: Postoperative adhesions are among the major causes of morbidity and mortality following abdominal surgery. As an antioxidant and antiinflamatory agent, the potential effect of ethyl pyruvate on adhesion prevention has not been clearly studied. We aimed to investigate the possible anti-adhesive effect of ethyl pyruvate compared with an effective barrier membrane, Seprafilm, in a rat cecal abrasion model. Materials and Methods: Male Wistar albino rats separated into three adhesion model groups (n = 8, each) with applications of different agents during surgery: control (intraperitoneal normal saline), Seprafilm group (intraperitoneal Seprafilm), and Ethyl pyruvate group (40 mg/kg intraperitoneal ethyl pyruvate). Postoperative adhesion was graded both macroscopically and histopathologically. Malondialdehyde and nitric oxide levels were determined from tissue samples for assessment of oxidative stress. Results: Seprafilm and Ethyl pyruvate groups had lower adhesion scores (both macroscopic and microscopic) and decreased malondialdehyde and nitric oxide levels compared to the control group (p < 0.05 for all parameters). The results were comparable for both Seprafilm and Ethyl pyruvate groups for all parameters (p > 0.05). Conclusions: Intraperitoneal ethyl pyruvate application reduced the incidence and the extent of postoperative adhesions in rat cecal abrasion model. Ethyl pyruvate also had comparable overall efficacy for adhesion prevention as Seprafilm. 相似文献
29.
Sinan Kahraman Selhan Karadereler Mutlu Cobanoglu Sinan Yilar Ayhan Mutlu Levent Onur Ulusoy Azmi Hamzaoglu 《European spine journal》2016,25(6):1665-1673
Purpose
The aim of this retrospective study was to evaluate the changes in the vertebral body and spinal canal area in a group of patients who had pedicle screw fixation under age 5 for the treatment of congenital spinal deformity at least 5 year follow-up.Methods
11 patients who had been operated due to spinal deformity under age 5 with who had a CT examination at least 5 years after the initial operation were included in the study. All patients underwent hemivertebrectomy and transpedicular fixation procedures at an average age of 3.18 years (range 2–5 years). All had preoperative CT to evaluate the congenital deformities. Measurements were done at the instrumented vertebrae as well as the un-instrumented ones above and below them to evaluate; vertebral body parameters, pedicle parameters and spinal canal area of upper instrumented vertebra (UIV), lower instrumented vertebra (LIV), upper adjacent un-instrumented vertebra and lower adjacent un-instrumented vertebra.Results
The average follow-up was 7.2 (range 5–12) years. Six of the patients were over age 10 during the final CT examination while 5 were at age 7. Female-to male ratio was 8–3. Measurement of all the parameters in 22 instrumented and 22 non-instrumented segments showed a proportional increase rather than a decrease at each segment. The percentage of canal area growth at UIV and LIV was 21 and 17.5 %, respectively.Conclusion
Pedicle screw instrumentation has no adverse effect on further spinal body, pedicle and canal growth and does not result in iatrogenic spinal canal stenosis.30.
Mutlu L Brandt C Kwidzinski E Sawitzki B Gimsa U Mahlo J Aktas O Nitsch R van Zwam M Laman JD Bechmann I 《Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale》2007,178(4):542-553
Despite transient, myelin-directed adaptive immune responses in regions of fiber tract degeneration, none of the current models
of fiber tract injuries evokes disseminated demyelination, implying effective mechanisms maintaining or re-establishing immune
tolerance. In fact, we have recently detected CD95L upregulation accompanied by apoptosis of leukocytes in zones of axonal
degeneration induced by entorhinal cortex lesion (ECL), a model of layer-specific axonal degeneration. Moreover, infiltrating
monocytes readily transformed into ramified microglia exhibiting a phenotype of immature (CD86+/CD80−) antigen-presenting
cells. We now report the appearance of the axonal antigen neurofilament-light along with increased T cell apoptosis and enhanced
expression of the pro-apoptotic gene Bad in cervical lymph nodes after ECL. In order to test the functional significance of
such local and systemic depletory/regulatory mechanisms on subsequent immunity to central nervous system antigens, experimental
autoimmune encephalomyelitis was induced by proteolipid protein immunization 30 days after ECL. In three independent experiments,
we found significantly diminished disease scores and infiltrates in lesioned compared to sham-operated SJL mice. This is consistent
with a previous meta-statistical analysis (Goodin et al. in Neurology 52:1737–1745, 1999) rejecting the O-hypothesis that brain trauma causes or exacerbates multiple sclerosis. Conversely, brain injuries may involve
long-term tolerogenic effects towards brain antigens.
Leman Mutlu, Christine Brandt, Jon D. Laman, and Ingo Bechmann have contributed equally. 相似文献