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151.
Oculocutaneous albinism 总被引:2,自引:0,他引:2
JF Okulicz RS Shah RA Schwartz CK Janniger 《Journal of the European Academy of Dermatology and Venereology》2003,17(3):251-256
Oculocutaneous albinism represents a group of inherited skin disorders characterized by a generalized reduction of cutaneous, ocular and pilar pigmentation from the time of birth. Oculocutaneous albinism types 1 and 2 are the most common, but several other types have been described. A defect in the melanin synthesis pathway, resulting in reduced formation of melanin, is responsible for oculocutaneous albinism. Aetiology, clinical manifestations, diagnosis and management are discussed. 相似文献
152.
Cutaneous Crohn''s disease mimicking Melkersson–Rosenthal syndrome: treatment with methotrexate 总被引:1,自引:0,他引:1
V Tonkovic-Capin† SS Galbraith† RS Rogers III ‡ DG Binion§ KB Yancey† 《Journal of the European Academy of Dermatology and Venereology》2006,20(4):449-452
A woman with a 5-year history of unilateral orofacial granulomatosis required repeated evaluations (including sequential colonoscopies) to establish the diagnosis of cutaneous Crohn's disease, a condition that proved responsive to low doses of oral methotrexate administered weekly. To our knowledge this is the first report describing the use of methotrexate for treatment of orofacial granulomatosis caused by underlying Crohn's disease. 相似文献
153.
The tongue in clinical diagnosis 总被引:1,自引:0,他引:1
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S Satyanarayana AT Kalghatgi A Muralidhar RS Prasad KZ Jawed A Trehan 《Medical Journal Armed Forces India》2002,58(1):33-37
Lymphadenopathy is the commonest presentation in HIV positive individuals. Fine needle aspiration cytology of 196 HIV positive patients was studied during six monthly review. 75% paients in this study who were asymptomatic were detected to have lymphadenopathy during the surveillance. 82% had lymph nodes smaller than 1cm size. Lymphadenopathy at more than one site was observed in 46.8% cases. Commonest opportunistic infection noticed was tuberculosis (TB) in 34.2%. Cyto-morphologically reactive pattern with Add fast bacilli (AFB) positivity was observed in 16.4% of TB cases. In 2.9% cases AFB were detected even in the tissue fluid. Negative images of AFB were observed in the macrophages in 3 cases. TB was detected with equal frequency in both asymptomatic and symptomatic groups. Axillary nodes pose problem due to deeper location. False positives were a case of dermatopathic lymphadenopathy and a case of Kimura''s disease. False negatives include two cases of TB lymphadenitis. Pathogens should be looked for irrespective of cyto-morphology. Biopsy should be done to confirm cases of lymphomas. Fine needle aspiration cytology should be included in the protocol of six monthly review of HIV infected cases.KEY WORDS: AIDS, FNAC, HIV, Lymph node, Tuberculosis 相似文献
157.
Clare RS Patterson Katharine Acland Ramona Khooshabeh 《The Australasian journal of dermatology》2009,50(4):294-296
Naevus of Ota is a dermal melanocytosis most commonly found in black or Asian skin and is usually a benign malformation, but with a low risk of melanoma. We describe a 32-year-old Caucasian man with an acquired naevus of Ota with subtle pigmentation, in which a melanocytic papule developed. The lesion, deceptively, had no clinically suspicious features, but investigation revealed an aggressive cutaneous malignant melanoma, extensive orbital ring melanocytosis and metastatic brain and subsequent liver disease. 相似文献
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脂质体载体材料卵磷脂的制备及质量标准研究 总被引:4,自引:0,他引:4
目的:制备脂质体载体材料卵磷脂。方法:以新鲜鸡蛋为原料提取并制备了卵磷脂,并对卵磷脂的纯度,含量,氧化程度以及质量标准进行考察。结果:试验制备的卵磷脂为色谱均一的物质,含量高于98%,其氧化程度低,各项质量指标均符合美国药典规定。结论:结果表明,试验制得的卵磷脂可作为制备脂质体的载体材料。 相似文献