Children's ratings of peers presented as mentally retarded and physically handicapped

Third- and sixth-grade children were shown slides and tapes presenting target children as either (a) physically nonhandicapped and nonretarded, (b) physically handicapped only, (c) mentally retarded only, or (d) physically handicapped and mentally retarded. All children were rated more favorably by third graders than sixth graders and more favorably by boys than girls. Physically handicapped target children were rated more favorably than were nonhandicapped children on behavioral intentions measures but were not rated differently on an attitude scale; retarded children were also rated more favorably than were nonretarded children on the former measures but less favorably on the attitude scale. Significant interactions were noted and implications of the results discussed.     

Treatment of alcohol-related liver disease with (+)-cyanidanol-3: a randomised double-blind trial.

A randomised double-blind trial of (+)-cyanidanol-3(Catechin), 2 g/day versus placebo, was carried out in 40 patients with pre-cirrhotic alcohol-related liver disease over a three month period. Twenty received the active drug and 20 placebo; one non-compliant patient in the treatment group was withdrawn. Forty-one per cent (16/39) abstained from alcohol and showed significant improvements (P < 0.005) in mean values for serum aspartate transaminase, serum gamma glutamyl transpeptidase, and mean corpuscular volume. Ten of the 16 showed overall histological improvement on liver biopsy. Fifty-nine pr cent (23/39) continued to drink, though significantly reducing their mean daily alcohol intake (P < 0.001). No significant changes occurred in this group in mean serum enzyme values, though the mean value for mean corpuscular volume improved significantly (P < 0.01) and 16 of the 23 showed overall histological improvement. Changes occurred irrespective of treatment with Catechin which suggests that, over a three month period, this drug did not influence the course of alcohol-related liver disease.