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721.
Mahtab Vasigh Mohammadreza Karoobi Mahnaz Montazeri Golnaz Moradi Hoda Asefi Abolfazl Gilani Seyed mostafa Meshkati yazd 《Clinical Case Reports》2022,10(5)
Psoas tuberculosis abscess is very rarely detected primarily without an adjacent vertebral cold abscess. Early diagnosis prevents unnecessary operations and life‐threatening complications. 相似文献
722.
Aziz Rezapour Aghdas Souresrafil Mohammad Barzegar Mohammadreza Sheikhy-Chaman Parvin Tatarpour 《Clinical genetics》2023,103(5):513-528
In recent years, massively parallel sequencing or next generation sequencing (NGS) has considerably changed both the research and diagnostic fields, and rapid developments have led to the combination of NGS techniques in clinical practice, ease of analysis, and detection of genetic mutations. This article aimed at reviewing the economic evaluation studies of the NGS techniques in the diagnosis of genetic diseases. In this systematic review, scientific databases (PubMed, EMBASE, Web of Science, Cochrane, Scopus, and CEA registry) were searched from 2005 to 2022 to identify the related literature on the economic evaluation of NGS techniques in the diagnosis of genetic diseases. Full-text reviews and data extraction were all performed by two independent researchers. The quality of all the articles included in this study was evaluated using the Checklist of Quality of Health Economic Studies (QHES). Out of 20 521 screened abstracts, 36 studies met the inclusion criteria. The mean score of the QHES checklist for the studies was 0.78 (high quality). Seventeen studies were conducted based on modeling. Cost-effectiveness analysis, cost-utility analysis, and cost-minimization analysis were done in 26 studies, 13 studies, and 1 study, respectively. Based on the available evidence and findings, exome sequencing, which is one of the NGS techniques, could have the potential to be used as a cost-effective genomic test to diagnose children with suspected genetic diseases. The results of the present study support the cost-effectiveness of exome sequencing in diagnosing suspected genetic disorders. However, the use of exome sequencing as a first- or second-line diagnostic test is still controversial. Most studies have been conducted in high-income countries, and research on the cost-effectiveness of NGS methods is recommended in low- and middle-income countries. 相似文献
723.
Nasim Khajavirad Mohammadreza Salehi Abdolkarim Haji ghadery Hossein Khalili Mehran Arab Ahmadi Seyed Ali Dehghan Manshadi Ali Zare Dehnavi 《Clinical Case Reports》2022,10(2)
In 2020, the SARS‐COV‐2 disease (COVID‐19) imposed huge challenges on the health, economic, and political systems, and by the end of the year, hope had been born with the release of COVID‐19 vaccines aimed at bringing the pandemic to an end. However, the COVID‐19 vaccination programs have sparked several concerns and ongoing debates over safety issues. Here, we presented three cases of patients with serious adverse events, encephalopathy, vaccine‐induced thrombotic thrombocytopenia, and leukocytoclastic vasculitis, after receiving the ChAdOx1 nCoV‐19 vaccine. Therefore, it is critical to investigate and report the occurrence of adverse reactions following vaccination, particularly serious ones, as it contributes to the growing body of research and assists clinicians in better diagnosing and managing them. 相似文献
724.
Greg Roebuck Mojtaba Lotfaliany Bruno Agustini Malcolm Forbes Mohammadreza Mohebbi John McNeil Robyn L. Woods Christopher M. Reid Mark R. Nelson Raj C. Shah Joanne Ryan Anne B. Newman Alice Owen Rosanne Freak-Poli Nigel Stocks Michael Berk ASPREE Investigator Group 《Acta psychiatrica Scandinavica》2023,147(1):92-104
725.
Danial FazilatPanah Nahid Ahmadi Dariush Moslemi Masoumeh Karimi Alireza Taji Mansoureh Dehghani Ali Emadi Torghabeh Zahra Keshtpour Amlashi Mohammadreza Saghafi Maedeh Alsadat Fatemi 《Clinical Case Reports》2021,9(10)
Despite the fact that prostate cancer is the most prevalent cancer in men, metastases to the central nervous system including leptomeningeal involvement by prostate carcinoma is a rare event. The prognosis of metastatic prostate cancer is very poor due to lack of CNS penetrating therapeutic agents. 相似文献
726.
Gregory Roebuck Michael Mazzolini Mohammadreza Mohebbi Julie A. Pasco Amanda L. Stuart Malcolm Forbes Michael Berk Lana Williams 《Acta psychiatrica Scandinavica》2023,148(1):47-59
Objective
Certain psychiatric disorders, including depression, appear to impact adversely on bone health. Anxiety disorders are highly prevalent but few studies have examined their effects on bone tissue. This study investigated the effect of anxiety disorders on bone mineral density (BMD).Methods
This prospective cohort study used data from the Geelong Osteoporosis Study. Participants were women and men aged ≥20 years randomly selected from the electoral roll and followed up for a mean of 14.7 and 11.0 years, respectively. Participants were assessed for a lifetime history of an anxiety disorder using the Structured Clinical Interview for DSM-IV-TR. BMD in the lumbar spine and femoral neck was measured using dual-energy x-ray absorptiometry.Results
Eight hundred and ninety women and 785 men participated in the study. Adjusting for sociodemographic, biometric and lifestyle factors, medical comorbidities and medication use, anxiety disorders were associated with reduced BMD at the lumbar spine (partial η2 = 0.006; p = 0.018) and femoral neck (partial η2 = 0.006; p = 0.003) in men. These associations became non-significant when men with a history of comorbid mood disorders were excluded from the analysis. There was no significant association between anxiety disorders and BMD in women (p ≥ 0.168).Conclusions
Anxiety disorders are associated with reduced BMD in men. This effect may be mediated by comorbid depression. 相似文献727.
Navid Neyshaburinezhad Nooshin Shirzad Mohammadreza Rouini Soha Namazi Mohammadreza Khoshayand Alireza Esteghamati Manouchehr Nakhjavani Hengameh Ghasim Yvonne Gloor Youssef Daali Yalda H. Ardakani 《Basic & clinical pharmacology & toxicology》2023,132(6):485-497
The present study evaluates the influence of type 2 diabetes (T2D) on important CYP450 (CYP) isoforms and P-glycoprotein (Pgp) transporter activities before and 3 months after an intensifying treatment regimen involving 40 patients. Results have been compared with 21 non-T2D healthy participants (the control group). CYPs and Pgp activities were assessed after administering the Geneva cocktail. The mean metabolic ratios (MR) for CYP2B6 (1.81 ± 0.93 versus 2.68 ± 0.87), CYP2C19 (0.420 ± 0.360 versus 0.687 ± 0.558) and CYP3A4/5 (0.487 ± 0.226 versus 0.633 ± 0.254) significantly decreased in T2D patients compared to the control group (p < 0.05). CYP2C9 (0.089 ± 0.037 versus 0.069 ± 0.017) activities slightly increased in diabetic patients, and no difference was observed regarding CYP1A2 (0.154 ± 0.085 versus 0.136 ± 0.065), CYP2D6 (1.17 ± 0.56 versus 1.24 ± 0.83), and Pgp activities in comparison to the control group. Three months after the intensifying treatment regimen, MRs of CYP2C9 (0.080 ± 0.030) and CYP3A4/5 (0.592 ± 0.268) improved significantly and were not statistically different compared to the control group (P > 0.05). Several covariables, such as inflammatory markers (IL-1β and IL-6), genotypes, diabetes and demographic-related factors, were considered in the analyses. The results indicate that chronic inflammatory status associated with T2D modulates CYP450 activities in an isoform-specific manner. 相似文献
728.
Mohammadreza Mobayen Hossein Torabi Parissa Bagheri Toolaroud Mohammad Tolouei Anoush Dehnadi Moghadam Mohammad Saadatmand Habib EslamiKenarsari Alireza Feizkhah Mohammad Javad Ghazanfari Joseph Osuji Pooyan Ghorbani Vajargah Samad Karkhah 《International wound journal》2023,20(8):3204-3211
Patients with acute burns are more vulnerable to COVID-19 because of physiologically weak immune systems. This study aimed to assess and compare individual characteristics, clinical features, and clinical outcomes of acute burn among COVID-19 and non-COVID-19 patients. A retrospective study, with data collected from 611 acute burn patients with or without a COVID-19 diagnosis referred to a burn centre in Iran. Data were collected from April 2020 to 2021. The mean age of acute burns patients with COVID-19 was higher compared with acute burns patients with non-COVID-19 (47.82 vs. 32.59 years, P < .001). Acute burns occurred more frequently in COVID-19 patients with comorbidities compared with non-COVID-19 patients (48.72% vs. 26.92%, P = .003). 58.97% of COVID-19 patients and 55.42% of non-COVID-19 patients had grade II & III and II burns, respectively (P < .001). The mean total body surface area of the burn was higher in COVID-19 patients compared with non-COVID-19 patients (32.69% vs. 16.22%, P < .001). Hospitalisation in the intensive care unit (ICU) was higher in COVID-19 patients than in non-COVID-19 patients (76.92% vs. 15.73%, P < .001). Length of stay in hospital and ICU, the cost of hospitalisation, and waiting time for the operating room was higher in COVID-19 patients compared with non-COVID-19 patients (15.30 vs. 3.88 days, P < .001; 9.61 vs. 0.75 days, P < .001; 30 430 628.717 vs. 10 219 192.44 rials, P = .011; 0.84 vs. 0.24 min, P < .001, respectively). Intubation and mortality in-hospital were higher in COVID-19 patients compared with non-COVID-19 patients (41.02% vs. 6.99%, P < .001; 35.90% vs. 6.12%, P < .001, respectively). Therefore, it is recommended that health managers and policymakers develop a care plan to provide high-quality care to acute burns patients with COVID-19, especially in low-income countries. 相似文献
729.
Khabbazi Alireza Gadakchi Leyla Moslemi Mohammadreza Khalaji Amirreza Esalatmanesh Kamal Ziarati Yazdeli Asma Hajialilo Mehrzad Malek Mahdavi Aida 《Clinical rheumatology》2023,42(6):1537-1544
Clinical Rheumatology - The aim of the present study was to provide real-world evidence for factors predicting long-term remission in a longitudinal study of rheumatoid arthritis (RA) patients.... 相似文献
730.
Mehdi Moghaddasi Mohammadreza Ghassemi Mohammad Shekari Yazdi Seyed Amir Hasan Habibi Nafiseh Mohebi Azadeh Goodarzi 《Clinical Case Reports》2021,9(9)
HMS can have neurologic MS like manifestations. It is urgent to do more research and report probable unknown associations of HMS for its better management. 相似文献