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941.
942.
943.
Hirotaka Suzuki Takuya Ishikawa Eizaburo Ohno Tadashi Iida Kota Uetsuki Jun Yashika Kenta Yamada Masakatsu Yoshikawa Kazuhiro Furukawa Masanao Nakamura Takashi Honda Masatoshi Ishigami Hiroki Kawashima Mitsuhiro Fujishiro 《Pancreatology》2021,21(4):682-687
Background/ObjectivesWe aimed to examine therapeutic efficacy and prognosis prediction of autoimmune pancreatitis (AIP) using shear wave elastography (SWE) and shear wave dispersion (SWD) in transabdominal ultrasound (US).MethodsThe subjects were 23 patients with diffuse type 1 AIP who underwent SWE and SWD, and 34 controls with a normal pancreas. Elasticity and dispersion were defined as the pancreatic elastic modulus (PEM) and dispersion slope, respectively. PEM and dispersion slope were compared between AIP and control cases, and the short-term therapeutic effect and long-term prognosis were examined.ResultsPEM (30.9 vs. 6.6 kPa, P < 0.001) and dispersion slope (15.3 vs. 13.0 (m/sec)/kHz, P = 0.011) were significantly higher in AIP cases than in controls. Among the 17 AIP patients followed-up in two weeks after treatment, these parameters were 12.7 kPa and 10.5 (m/sec)/kHz with median decrease rate of 37.2% and 32.8%, respectively, which were significantly higher than the change in the size of pancreatic parenchyma (14.4%, P = 0.026). Fourteen of these subjects were followed up for >12 months, during which 2 had relapse; diabetes improved in 5 and worsened in 2; in 60% of cases, the pancreatic parenchyma was atrophied. The % change in PEM after two weeks was tended to be higher in non-atrophy cases.ConclusionSWE and SWD measurement in US may be useful for quantitative assessment of AIP and evaluation of short-term treatment efficacy. 相似文献
944.
Akihiro Nakajima MD Makoto Araki MD PhD Osamu Kurihara MD PhD Yoshiyasu Minami MD PhD Tsunenari Soeda MD PhD Taishi Yonetsu MD Filippo Crea MD FACC Masamichi Takano MD PhD Takumi Higuma MD PhD Tsunekazu Kakuta MD PhD Tom Adriaenssens MD PhD Hang Lee PhD Sunao Nakamura MD PhD FACC Ik-Kyung Jang MD PhD FACC 《Catheterization and cardiovascular interventions》2021,97(4):634-645
945.
946.
947.
Takatoshi Shigeta Kaoru Okishige Hideshi Aoyagi Takuro Nishimura Rena A. Nakamura Naruhiko Ito Yusuke Tsuchiya Mitsutoshi Asano Tsukasa Shimura Hidetoshi Suzuki Manabu Kurabayashi Yuichi Fukami Shinya Sakita Takehiko Keida Tetsuo Sasano Kenzo Hirao Yasuteru Yamauchi 《Pacing and clinical electrophysiology : PACE》2019,42(2):230-237
948.
949.
Takashi Mitsuki Muneyoshi Kimura Hideki Araoka Kosei Kageyama Shinsuke Takagi Go Yamamoto Shigeki Nakamura Yoshitsugu Miyazaki Naoyuki Uchida Akiko Yoneyama Shuichi Taniguchi 《Journal of infection and chemotherapy》2019,25(4):289-292
Few cases of cryptococcal infection following umbilical cord blood transplantation (UCBT) have been reported. We report a case, where cryptococcal infection occurred soon after rapidly reducing the dose of tacrolimus in a UCBT recipient who received micafungin prophylaxis during the early phase of transplantation. The etiology of cryptococcal infection following allogeneic hematopoietic stem cell transplantation (allo-HSCT), including UCBT, might be associated with rapid dose-reduction of calcineurin inhibitors, such as tacrolimus during early phase of allo-HSCT. To our knowledge, this is the first English-language report to describe in detail a case of cryptococcal meningitis with fungemia during early phase of UCBT. 相似文献
950.
Kazushi Yamairi Kentaro Ido Shigeki Nakamura Makoto Niki Waki Imoto Wataru Shibata Hiroki Namikawa Hiroki Fujimoto Koichi Yamada Hirohisa Nakamae Masayuki Hino Yukihiro Kaneko Yoshitsugu Miyazaki Hiroshi Kakeya 《Journal of infection and chemotherapy》2019,25(4):307-310
Aspergillus species are a major cause of life-threatening infections in immunocompromised hosts, and the most common pathogen of invasive aspergillosis is Aspergillus fumigatus. Recently, the development of molecular identification has revealed cryptic Aspergillus species, and A. felis is one such species within the Aspergillus section Fumigati reported in 2013.We describe a case of invasive pulmonary aspergillosis caused by A. felis in a 41-year-old Japanese woman diagnosed with myelodysplastic syndrome. She presented with fever 19 days after undergoing autologous peripheral blood stem cell transplantation and was clinically diagnosed with invasive pulmonary aspergillosis. Bronchoscopy and bronchoalveolar lavage were performed for definitive diagnosis. The β-tubulin genes of the mold isolated from the bronchoalveolar lavage fluid, and sequenced directly from the PCR products using a primer pair were found to have 100% homology with A. felis. We successfully treated the patient with echinocandin following careful susceptibility testing.To the best of our knowledge, this is the first published case reporting the clinical course for diagnosis and successful treatment of invasive aspergillosis by A. felis. 相似文献