全文获取类型
收费全文 | 8776篇 |
免费 | 370篇 |
国内免费 | 65篇 |
专业分类
耳鼻咽喉 | 69篇 |
儿科学 | 155篇 |
妇产科学 | 88篇 |
基础医学 | 1059篇 |
口腔科学 | 214篇 |
临床医学 | 531篇 |
内科学 | 2508篇 |
皮肤病学 | 78篇 |
神经病学 | 638篇 |
特种医学 | 494篇 |
外科学 | 1585篇 |
综合类 | 63篇 |
预防医学 | 207篇 |
眼科学 | 135篇 |
药学 | 457篇 |
中国医学 | 18篇 |
肿瘤学 | 912篇 |
出版年
2023年 | 32篇 |
2022年 | 89篇 |
2021年 | 131篇 |
2020年 | 61篇 |
2019年 | 102篇 |
2018年 | 112篇 |
2017年 | 118篇 |
2016年 | 112篇 |
2015年 | 129篇 |
2014年 | 183篇 |
2013年 | 232篇 |
2012年 | 402篇 |
2011年 | 449篇 |
2010年 | 280篇 |
2009年 | 263篇 |
2008年 | 460篇 |
2007年 | 470篇 |
2006年 | 462篇 |
2005年 | 502篇 |
2004年 | 477篇 |
2003年 | 496篇 |
2002年 | 498篇 |
2001年 | 211篇 |
2000年 | 202篇 |
1999年 | 236篇 |
1998年 | 167篇 |
1997年 | 131篇 |
1996年 | 105篇 |
1995年 | 105篇 |
1994年 | 104篇 |
1993年 | 97篇 |
1992年 | 151篇 |
1991年 | 147篇 |
1990年 | 151篇 |
1989年 | 145篇 |
1988年 | 143篇 |
1987年 | 138篇 |
1986年 | 114篇 |
1985年 | 125篇 |
1984年 | 65篇 |
1983年 | 58篇 |
1982年 | 35篇 |
1981年 | 40篇 |
1979年 | 49篇 |
1978年 | 39篇 |
1977年 | 45篇 |
1974年 | 27篇 |
1971年 | 24篇 |
1969年 | 24篇 |
1967年 | 24篇 |
排序方式: 共有9211条查询结果,搜索用时 15 毫秒
21.
T Muramatsu M Ohata M Iida K Omori M Irako K Kitamura S Nakamura K Ogasawara M Koga Y Sezai 《Kyobu geka. The Japanese journal of thoracic surgery》1990,43(4):300-304
Thymolipoma is a very rare mediastinal tumor. We reported a case of 52-year-old female with thymolipoma which was located in the cervicomediastinal area. The chest X-ray film revealed an abnormal shadow in the superior mediastinum. Computed Tomography (CT) clearly showed the existence of a large mass in the left side of the trachea. The angiogram showed that there was a stenosis on the left brachiocephalic vein. On June 13, 1988, median sternotomy was performed. A large tumor, about 5.5 x 13 x 5.5 cm, was found arising from the left cervical area. This tumor was excised completely and thymolipoma was diagnosed histopathologically. The post-operative course was very satisfactory. 相似文献
22.
Hirofumi Fukushima Emiko Katou Kouji Nagayama Akira Shirachi Michio Sata 《Nihon Shokakibyo Gakkai zasshi》2006,103(6):661-666
A 80-year old man was referred to our hospital because of an elevation of serum amylase level. Diffuse enlargement of the pancreas was detected by abdominal computed tomography, and also diffuse narrowing of the main pancreatic duct was revealed using endoscopic retrograde cholangiopancreatography. The serum level of IgG was elevated to 3450mg/dl. Besides, on the 10th hospital day, petechia developed and the platelet level decreased to 1.5 x 10(4)/microl. The platelet-associated IgG, antiplatelet antibody and antinuclear antibody in serum were positive. The levels of serum complements were low. From all these findings the patient was diagnosed as autoimmune pancreatitis complicated with immune thrombocytopenia. The treatment with prednisolone was started, which was effective on each disease. The medication was suspended a year ago, and so far there is no data suggesting the recurrence of autoimmune pancreatitis or immune thrombocytopenia. 相似文献
23.
Tsunao Imamura Rie Takeshita Rikako Koyama Chikao Okuda Kazuo Takeuchi Masamichi Matsuda Masashi Hashimoto Goro Watanabe Hitoshi Yoshida Michio Imawari 《Digestive endoscopy》2006,18(4):303-307
Background: Pancreatic carcinoma is one of the most lethal cancers. Because pancreatic carcinoma is still very difficult to diagnose in its early stage, many of these patients will be considered unsuitable for surgery. If a cytological diagnosis is obtained at initial endoscopic retrograde cholangiopancreatography (ERCP), suitable treatment will be initiated without delay. Methods: To increase the number of exfoliated cells from the pancreatic duct, we devised a new technique, pancreatic duct lavage fluid (PDLF), following bronchoalveolar lavage fluid. The present paper reports the effectiveness of cytological examination using PDLF in the diagnosis of pancreatic carcinoma. We examined 18 pancreatic carcinoma cases. After the endoscopic retrograde pancreatography (ERP), PDLF was collected from a double‐lumen catheter inserted into the main pancreatic duct. Saline injected from the lumen for the injection, and PDLF was aspirated from the other lumen for the guidewire at the same time. The cytological examination was performed using PDLF. Results: Exfoliated cells were more frequently found in PDLF from all patients. In 15 cases (83%), cytological examination of PDLF revealed positive cytological results as the diagnosis of pancreatic carcinoma. Conclusion: Cytological examination using PDLF has a high sensitivity for detection of pancreatic carcinoma. The new examination, PDLF, is simple, safe and effective, so we expect PDLF to become widely popular. 相似文献
24.
25.
J Yamazaki H Ohsawa T Uchi M Iida M Wakakura K Okamoto H Hosoi T Morishita H Nakano Y Yabe 《呼吸と循環》1992,40(3):275-281
201Tl myocardial SPECT was performed in cases of dilated cardiomyopathy and valvular heart disease with left ventricular eccentric hypertrophy, and the two groups were compared from the standpoint of the mechanism of onset of myocardial disorders. Significant coefficients of correlation were seen between the Tl score and LVDd (r = 0.792, r = 0.785) and Tl score and LVEF (r = -0.634, r = -0.555) in both dilated cardiomyopathy and valvular heart disease. In cases of valvular heart disease, significant correlation coefficients (r = -0.756, r = -0.720) between LVDd and r-WR (relative-washout rate), and Tl score and r-WR were observed, but no such correlation was seen in dilated cardiomyopathy. In valvular heart disease, a decrease in myocardial perfusion associated with enlargement of the left ventricle appeared, while in dilated cardiomyopathy, there was a marked decrease in LVEF in proportion to the thallium defect. Therefore, it was assumed that left ventricular wall disorders occur due to myocardial metabolic disorders and coronary microcirculation disorders. 相似文献
26.
Significance of positive Queckenstedt test in patients with syringomyelia associated with Arnold-Chiari malformations. 总被引:2,自引:0,他引:2
Ten patients with syringomyelia associated with Arnold-Chiari Type I malformations were evaluated. In each patient, a manometric Queckenstedt test was performed with the neck in various positions. No patient showed evidence of a block to the flow of cerebrospinal fluid (CSF) with the neck in the extended position; however, all showed a complete CSF block with the neck in a flexed position. Posterior fossa decompression with a C1-2 laminectomy was performed in nine cases, after which Queckenstedt test demonstrated free CSF communication in all nine with the neck in extension, in a neutral position, and in flexion. Postoperative magnetic resonance imaging showed shrinkage of the syrinx in the patients who underwent surgery. It is suggested that obstruction of the CSF pathway at the foramen magnum produced by neck movement is of importance in the formation and progression of a syrinx. 相似文献
27.
We made an attempt to detect organic brain lesions in eight patients with myotonic dystrophy (MyD) using X-ray computed tomography (CT) and magnetic resonance imaging (MRI). The patients comprised seven men and one woman with ages ranging from 41 to 58 years (average 47 +/- 5.3 years). Seven patients had intellectual impairment assessed using an intelligence quotient test (WAIS-R < 70). CT scans were obtained in the axial plane with a slice thickness of 10 mm, and MRI scans were performed on a 1.5 tesla system in the axial and coronal sections with a slice thickness of 8 mm. CT scans displayed both marked sulcal and prominent ventricular enlargement in 6 of the 8 patients, indicating the presence of brain atrophy, and 3 cases had a few paraventricular low density area in the cerebral hemispheres. In contrast to CT, MRI study revealed more widespread brain parenchymatous lesions in all the 8 cases, showing the multiple foci of high signal intensity with varying size in the white matter on T2-weighted images and proton density-weighted images. No visible changes were detected on CT or MRI in the brain stem and cerebellum. The present study demonstrated that there exist organic cerebral lesions, predominantly located in the white matter in patients with MyD, regardless of focal neurological symptoms. The parenchymatous lesions in the brain can be detected with MRI, and lesser extent with CT, and are considered to be intimately correlated with intellectual deterioration commonly seen in patients with MyD. 相似文献
28.
Takayoshi Sakai Seiji Iida Mitsunobu Kishino Masaya Okura Mikihiko Kogo 《Journal of oral pathology & medicine》2006,35(6):376-378
Sialolipoma is a new variant of salivary gland lipoma, which was first proposed by Nagao et al. (Histopathology 2001; 38: 30) in 2001. We report this rare case of sialolipoma in the hard palate. A 60-year-old Japanese woman was referred to our department complaining of a painless swelling on the right side of the hard palate. Intra-oral examination revealed a soft, elastic, dome-shaped mass with 1 cm in diameter located in the posterior part of the hard palate. Magnetic resonance imaging examination revealed high intensity on T(1)-weighted image and isointensity on T(2)-weighted image. Incisional biopsy revealed that the tumor was encapsulated by fibrous tissue, consisted of adipose tissue, and also contained normal salivary gland tissue peripherally. First diagnosed as an ordinary lipoma of the hard palate, the tumor was excised. According to the recent criteria of histologic findings of sialolipoma, we rediagnosed the tumor as sialolipoma of the hard palate. 相似文献
29.
30.
Low doses of the Gn-RH agonist (buserelin, 30 micrograms) were given intranasally to 14 women with clomiphene ineffective hypothalamic amenorrhea three times daily for three weeks in order to study pituitary responses and to induce follicular maturation and ovulation. Clomiphene ineffective hypothalamic amenorrhea patients were classified into two groups by LH-RH stimulation test before the treatment. Group 1 was defined as having basal serum LH and FSH levels lower than 1.5 mIU/ml, LH and FSH peaks lower than 3mIU/ml by LH-RH stimulation test. Group 2 consisted of cases other than those in Group 1. While a significant increase in basal LH and FSH (p less than 0.01, p less than 0.001) and improvement in pituitary response to LH-RH stimulation test were observed in group 1, the basal levels of LH and FSH did not increase significantly and pituitary response to a LH-RH stimulation test was decreased in group 2. It is suggested that pituitary priming occurred in group 1 and pituitary desensitization occurred in group 2. None of 14 patients showed signs of follicular maturation during or after the treatment. The results demonstrated that the biphasic pituitary response to intranasal buserelin spray and the limit of its therapeutic use for the treatment of hypothalamic amenorrhea. 相似文献