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排序方式： 共有1743条查询结果，搜索用时 265 毫秒
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Christopher E. Kline Lora E. Burke Susan M. Sereika Christopher C. Imes Bonny Rockette-Wagner Dara D. Mendez Patrick J. Strollo Yaguang Zheng Stephen L. Rathbun Eileen R. Chasens 《Mayo Clinic proceedings. Mayo Clinic》2018,93(9):1290-1298
Objective
To examine the bidirectional relationship between weight change and obstructive sleep apnea (OSA) in the context of a behavioral weight loss intervention.Patients and Methods
Adults who were overweight or obese (N=114) participated in a 12-month behavioral weight loss intervention from April 17, 2012, through February 9, 2015. The apnea-hypopnea index (AHI), a marker of the presence and severity of OSA, was assessed at baseline, 6 months, and 12 months. Linear mixed models evaluated the effect of weight change on the AHI and the effect of OSA (AHI ≥5) on subsequent weight loss. Secondary analyses evaluated the effect of OSA on intervention attendance, meeting daily calorie goals, and accelerometer-measured physical activity.Results
At baseline, 51.8% of the sample (n=59) had OSA. Adults who achieved at least 5% weight loss had an AHI reduction that was 2.1±0.9 (adjusted mean ± SE) events/h greater than those with less than 5% weight loss (P<.05). Adults with OSA lost a mean ± SE of 2.2%±0.9% less weight during the subsequent 6-month interval compared with those without OSA (P=.02). Those with OSA were less adherent to daily calorie goals (mean ± SE: 25.2%±3.3% vs 34.8%±3.4% of days; P=.006) and had a smaller increase in daily activity (mean ± SE: 378.3±353.7 vs 1060.1±377.8 steps/d; P<.05) over 12 months than those without OSA.Conclusion
Behaviorally induced weight loss in overweight/obese adults was associated with significant AHI reduction. However, the presence of OSA was associated with blunted weight loss, potentially via reduced adherence to behaviors supporting weight loss. These results suggest that OSA screening before attempting weight loss may be helpful to identify who may benefit from additional behavioral counseling. 相似文献44.
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A. B. Elfant M.D. C. Korn R.N. L. Mendez M.D. M. J. Pello M.D. S. R. Peikin M.D. 《Diseases of the colon and rectum》1995,38(1):1-3
PURPOSE: The aim of this study was to determine if recall of informed consent is affected by the timing of obtaining informed consent before endoscopic procedures. METHODS: Sixty patients scheduled for colonoscopy or esophagogastroduodenoscopy were enrolled in this prospective, randomized study. Each patient received informed consent 24 to 72 hours or immediately before the procedure, and follow-up occurred one to three days postprocedure. RESULTS: There was no statistically significant difference in recall of informed consent or the individual elements of informed consent (indication, risks, benefits, alternatives) between the two groups. CONCLUSION: Recall of informed consent is similar whether consent is obtained immediately or several days before endoscopie procedures.Presented in part at the 10th World Congresses of Gastroenterology, Los Angeles, California, October 2 to 7, 1994. 相似文献
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Castano-Jaramillo Lina M. Yamazaki-Nakashimada Marco Antonio O’Farrill-Romanillos Patricia M. Muzquiz Zermeño David Scheffler Mendoza Selma C. Venegas Montoya Edna García Campos Jorge Alberto Sánchez-Sánchez Luz María Gámez González Luisa B. Ramírez López Jesús Moisés Bustamante Ogando Juan Carlos Vásquez-Echeverri Estefanía Medina Torres Edgar Alejandro Lopez-Herrera Gabriela Blancas Galicia Lizbeth Berrón Ruiz Laura Staines-Boone Aidé Tamara Espinosa-Padilla Sara Elva Segura Mendez Nora Hilda Lugo Reyes Saul O. 《Journal of clinical immunology》2021,41(7):1463-1478
Journal of Clinical Immunology - Patients with inborn errors of immunity (IEI) have a compromised or inappropriate immune response. Although they might be considered a high-risk group for severe... 相似文献
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