全文获取类型
收费全文 | 822篇 |
免费 | 52篇 |
专业分类
耳鼻咽喉 | 5篇 |
儿科学 | 18篇 |
妇产科学 | 9篇 |
基础医学 | 112篇 |
口腔科学 | 36篇 |
临床医学 | 69篇 |
内科学 | 189篇 |
皮肤病学 | 14篇 |
神经病学 | 82篇 |
特种医学 | 35篇 |
外科学 | 105篇 |
综合类 | 5篇 |
预防医学 | 95篇 |
眼科学 | 14篇 |
药学 | 28篇 |
中国医学 | 3篇 |
肿瘤学 | 55篇 |
出版年
2023年 | 7篇 |
2022年 | 12篇 |
2021年 | 32篇 |
2020年 | 13篇 |
2019年 | 24篇 |
2018年 | 34篇 |
2017年 | 23篇 |
2016年 | 27篇 |
2015年 | 38篇 |
2014年 | 47篇 |
2013年 | 56篇 |
2012年 | 66篇 |
2011年 | 76篇 |
2010年 | 32篇 |
2009年 | 24篇 |
2008年 | 55篇 |
2007年 | 48篇 |
2006年 | 47篇 |
2005年 | 40篇 |
2004年 | 35篇 |
2003年 | 33篇 |
2002年 | 32篇 |
2001年 | 6篇 |
2000年 | 8篇 |
1999年 | 12篇 |
1998年 | 3篇 |
1997年 | 6篇 |
1996年 | 3篇 |
1995年 | 4篇 |
1993年 | 2篇 |
1992年 | 2篇 |
1991年 | 2篇 |
1990年 | 3篇 |
1989年 | 4篇 |
1988年 | 2篇 |
1986年 | 1篇 |
1984年 | 1篇 |
1980年 | 1篇 |
1979年 | 3篇 |
1978年 | 2篇 |
1975年 | 1篇 |
1973年 | 2篇 |
1971年 | 2篇 |
1970年 | 1篇 |
1967年 | 2篇 |
排序方式: 共有874条查询结果,搜索用时 16 毫秒
51.
Yones Lotfi Tayebeh Ahmadi Abdollah Moossavi Enayatollah Bakhshi 《Auris, nasus, larynx》2019,46(1):64-69
Objective
Previous studies have shown that a subgroup of children with suspected (central) auditory processing disorder (SusCAPD) have insufficient ability to use binaural cues to benefit from spatial processing. Thus, they experience considerable listening difficulties in challenging auditory environments, such as classrooms. Some researchers have also indicated the probable role of binaural temporal fine structure (TFS) in the perceptual segregation of target signal from noise and hence in speech perception in noise. Therefore, in the present study, in order to further investigate the underlying reason for listening problems against background noise in this group of children, their performance was measured using binaural TFS sensitivity test (TFS-LF) as well as behavioral auditory lateralization in noise test, both of which are based on binaural temporal cues processing.Methods
Participants in this analytical study included 91 children with normal hearing and no listening problems and 41 children (9–12 years old) with SusCAPD who found it challenging to understand speech in noise. Initially, the ability to use binaural TFS was measured at three frequencies (250, 500 and 750 Hz) in both the groups, and the results of preliminary evaluations were compared between normal children and those with SusCAPD who participated in the study. Thereafter, the binaural performance of the 16 children with SusCAPD who had higher thresholds than the normal group at all three frequencies tested in TFS-LF test was examined using the lateralization test in 7 spatial locations.Results
Total 16 of the 41 children with SusCAPD who participated in this study (39%) showed poor performance on the TFS-LF test at all three frequencies, compared to both normal children and other children in the APD group (p < 0.05). Furthermore, children in the APD group with binaural TFS coding deficits at all three frequencies revealed significant differences in the lateralization test results compared to normal children (p < 0.05).Conclusion
Findings of the current study demonstrated that one of the underlying causes for the difficulty understanding speech in noisy environments experienced by a subgroup of children with SusCAPD can be the reduced ability to benefit from binaural TFS information. This study also showed that a reduced ability to use binaural TFS cues in the group of children with SusCAPD was accompanied by reduced binaural processing abilities in the lateralization test which also admit the presence of binaural temporal processing deficits in this group of children. 相似文献52.
Very late metastases after cancer therapy are not common. We report an exceptionnal case of breast carcinoma associated with pregnancy that reocurred in the form of brain metastasis 49 years after initial treatment. 相似文献
53.
Ayadi-Kaddour A Chelly-Enneifer I Goutallier-Ben Fadhel C Saïgi E Gharbi L Lahmar-Boufaroua A Ben Sassi L Khalfallah MT Mzabi-Regaya S 《La Tunisie médicale》2005,83(5):311-314
Primary intestinal T-cell lymphomas account for about 5% of all primary gastrointestinal lymphomas and are mostly associated with coeliac disease. Intestinal lymphomas are usually discovered during the 4th to 5th decade and constitute an exceptional complication of coeliac disease. This lymphoma is generally a high grade pleomorphic cell lymphoma with large cells. Our case concerned a 30 year old woman with a history of coeliac disease who developed a gastro-enteromesenteric lymphoma. Anatomopathological and immunohistochemical analysis showed an enteropathy associated T-cell lymphoma. We suggest that patients with coeliac disease unresponsive to a gluten free diet or with deteriorating clinical condition be investigated for complications such as enteropathy associated T-cell lymphoma. It is also important to avoid this complication by detecting asymptomatic form of coeliac disease that needs a gluten-free diet. 相似文献
54.
Rachdi R Kaabi M Zayene H Basly M Messaoudi F Messaoudi L Chibani M 《La Tunisie médicale》2005,83(2):67-72
Severe gravidic toxemia gives heavy maternal and foetal morbidity and mortality. The purpose of our study is to loosen the factors of bad maternal and foetal prognostic. It's a retrospective study about 100 cases of severe and complicated gravidic toxemia repertorieted in the maternity of Military Hospital of Tunis. Maternal morbidity is dominated by the complications of hypertension and a blood disorders. We raised 4 cases of eclampsia, 9 cases of retro placental hematome and 5 cases of HELLP syndrome. We don't deplore any maternal death. Perinatal mortality is 28.8%. The rate of delay intra-uterine growth was 43.8% and the prematurity 65.9%. More toxemia appears early during pregnancy more maternal and foetal prognostic is compromised. 相似文献
55.
Preoperative concurrent chemotherapy and radiation therapy in cervix cancer: preliminary results 总被引:2,自引:0,他引:2
Kochbati L Ben Ammar CN Benna F Hechiche M Boussen H Besbes M Ben Abdallah M Rahal K Ben Ayed F Ben Romdhane K Maalej M 《La Tunisie médicale》2005,83(3):146-149
This is a retrospective study of patients treated for cervix cancer staged IB2, IIA or IIB with bulky tumor (> 4cm). Treatment was concurrent radiotherapy (45Gy with 1,8Gy daily fraction) and chemotherapy (5 cycles of Platinum 40mg/m2/week). All patients underwent Brachytherapy (15Gy on the reference isodose according to Paris system) followed by surgery (radical abdominal hysterectomy and bilateral pelvic lymphadenectomy: Piver 3) Between October 1999 and December 2002, forty five patients were treated in this protocol. Median age was 46 years (21- 68). Histology was squamous cell carcinoma in 93% and glandular carcinoma in 7%. Average external radiation dose was 44Gy (20-50). Ninety three percent of patients had at least 3 cycles of chemotherapy and 46,5% received the planned 5 cycles. On the operative specimens, there was 62,5% complete response and only 7 pelvic node involvement (17,5%). Four postoperative complications were noted (one vascular injury, one urinary fistula, one phlebitis and one lymph collection). Preoperative combined radiotherapy and chemotherapy in the early bulky stages of uterine cervix cancer is well tolerated and "gives" a high rate of sterilisation. There was no increase in surgical morbidity. 相似文献
56.
57.
Cherif L Khiari K Ben Abdallah N Kourda N Kaaroud H Ali IH Lakhoua Y Ben Hmida F El Younsi F Friaa S Sfaxi M Ben Moussa F Ben Jilani S Ayed M Ben Maïz H 《Néphrologie & thérapeutique》2005,1(4):247-251
The emphysematous pyelonephritis is a rare and severe renal infection characterized by the presence of gas in renal parenchyma and its perirenal spaces. We report two cases of emphysematous pyelonephritis in two diabetic women (53 and 50 years old respectively). In the first case, the treatment was based on nephrectomy because of the presence of a septic shock and three risk factors, which are acute renal failure, hematuria and thrombopenia. In the second case, the treatment was only medical. The evolution was favorable in the two cases. We insist in this article that this diagnosis should be considered in every female diabetic patient having severe acute pyelonephritis resistant to a well-conducted medical treatment. 相似文献
58.
Fourati-Ben Fguira L Fotso S Ben Ameur-Mehdi R Mellouli L Laatsch H 《Research in microbiology》2005,156(3):341-347
A new actinomycete strain, designated US80 and producing antimicrobial activities against Gram-positive and Gram-negative bacteria and fungi, was isolated from Tunisian oasis soil. Cultural characteristic studies strongly suggested that this strain belongs to the genus Streptomyces. The nucleotide sequence of the 16S rRNA gene (1517 pb) of Streptomyces sp. strain US80 exhibited close similarity (97-98%) with other Streptomyces 16S rRNA genes. Similarity of 98% was obtained with the 16S rRNA gene of Streptomyces roseoflavus, which produces the aminoglycoside antibiotic flavomycin. Study of the influence of different nutritional compounds on production of bioactive molecules showed that the highest antimicrobial activities were obtained when glucose at 1% (w/v) was used as sole carbon source in the presence of magnesium. Extraction of fermentation broth of Streptomyces sp. strain US80 and various separation and purification steps led to isolation of three pure active molecules. The chemical structure of these three compounds, named irumamycin (1a), X-14952B (1b) and 17-hydroxy-venturicidin A (1c), was established on the basis on their IR, ESI-MS, 1H and 13C/APT NMR data and by comparison with reference data from the literature. 相似文献
59.
Kaaroud H Khiari K Beji S Cherif L Ben Abdallah N Ben Moussa F Ayed K Ben Abdallah T Ben Maïz H 《La Tunisie médicale》2004,82(2):214-218
Post-transplant diabetes mellitus (PTDM) is a frequent complication of renal transplantation. It has a prevalence rate ranging from 3 to 46%. We undertook a retrospective study of 175 nondiabetic renal transplant recipients to determine the prevalence rate, clinical characteristics, and risk factors of PTDM in kidney transplant recipients in our region. Thirty five patients (20%) developed PTDM, 50% were diagnosed by 3 months post transplantation. Eight patients (22.8%) were insulin recurrent. PTDM was independent of kidney source, family history of diabetes, age, sex, incidence of acute rejection, body weight gain, steroid or cyclosporine dose, use of beta-blockers and cytomegalovirus infection. Acturial 5 years survival was 79.4% in the diabetic compared to 80.5% in the control group. Patient survival was similar in the two groups. We conclude that PTDM is frequent in our patients. No significant risk factors of PTDM were identified in this study. 相似文献
60.
Hajri R Rezgui L Ben Miled M Chekili S Laatar A Kassab S Farah F Hendaoui L Zakraoui L 《La Tunisie médicale》2004,82(11):1048-1051
Jaccoud's arthropathy (JA) is a chronic deformity affecting hands and feet, which are voluntarily correctable by the patients. JA was usually reported in association with rheumatic fever and systemic lupus erythematosus. We describe an exceptional association between a pyrophosphate arthropathy and JA of the hands. It is a 48-year-old woman, having a 13 years history of polyarthritis involving shoulders, elbows, hips and knees, and 4 years after, a progressive unlar deviation of the fingers of the hands. Calcium pyrophosphate dihydrate crystals were identified in the synovial knee biopsy. Hands x-rays as RMI don't identify erosions and confirmed the JA. 相似文献