全文获取类型
收费全文 | 8339篇 |
免费 | 670篇 |
国内免费 | 14篇 |
专业分类
耳鼻咽喉 | 65篇 |
儿科学 | 384篇 |
妇产科学 | 200篇 |
基础医学 | 1129篇 |
口腔科学 | 97篇 |
临床医学 | 994篇 |
内科学 | 1534篇 |
皮肤病学 | 181篇 |
神经病学 | 907篇 |
特种医学 | 135篇 |
外科学 | 976篇 |
综合类 | 64篇 |
一般理论 | 12篇 |
预防医学 | 1250篇 |
眼科学 | 64篇 |
药学 | 536篇 |
中国医学 | 6篇 |
肿瘤学 | 489篇 |
出版年
2024年 | 24篇 |
2023年 | 171篇 |
2022年 | 230篇 |
2021年 | 512篇 |
2020年 | 315篇 |
2019年 | 470篇 |
2018年 | 485篇 |
2017年 | 351篇 |
2016年 | 328篇 |
2015年 | 308篇 |
2014年 | 465篇 |
2013年 | 518篇 |
2012年 | 826篇 |
2011年 | 778篇 |
2010年 | 330篇 |
2009年 | 260篇 |
2008年 | 527篇 |
2007年 | 430篇 |
2006年 | 367篇 |
2005年 | 330篇 |
2004年 | 274篇 |
2003年 | 220篇 |
2002年 | 205篇 |
2001年 | 24篇 |
2000年 | 12篇 |
1999年 | 22篇 |
1998年 | 26篇 |
1997年 | 17篇 |
1996年 | 14篇 |
1995年 | 11篇 |
1994年 | 12篇 |
1993年 | 5篇 |
1992年 | 8篇 |
1991年 | 7篇 |
1990年 | 6篇 |
1987年 | 8篇 |
1986年 | 6篇 |
1985年 | 5篇 |
1984年 | 8篇 |
1983年 | 5篇 |
1981年 | 7篇 |
1979年 | 8篇 |
1978年 | 8篇 |
1977年 | 8篇 |
1976年 | 7篇 |
1975年 | 5篇 |
1974年 | 5篇 |
1972年 | 5篇 |
1968年 | 4篇 |
1967年 | 5篇 |
排序方式: 共有9023条查询结果,搜索用时 15 毫秒
11.
PURPOSE: To assess the utility and practicality of an evidence-based format in internal medicine attending rounds. METHOD: Two randomly selected teams of residents and medical students in the internal medicine program at the Montefiore Medical Center participated in "Evidence-Based Medicine Attending Month." The process entailed the development of patient-based, searchable questions, a search for the evidence, the critical appraisal of the retrieved literature, and the application of the evidence to the care of the patient. At the last meeting, participants evaluated each case by answering three questions about whether the process (1) had changed the medical management of the patient during the admission, (2) had changed the way they would manage similar patients in the future, and (3) had informed them about the disease process in general. RESULTS: A total of 12 of 16 formal EBM questions were developed and assessed (75% completion rate) during the four-week period, in addition to the standard background literature reviews usually performed. Twenty-two articles were retrieved and critically appraised. The evaluation demonstrated that 50% of the participants felt the process had changed the active management of patients currently treated by the team, 75% reported that the process would affect the care of future patients with comparable medical problems, and over 90% believed the program had informed them about the disease process. CONCLUSIONS: The formal EBM approach was conveniently implemented and enhanced the learning experience of the participants. It helped inform students' and residents' patient care at the time and their attitudes towards future patients. Hence, it is both practical and useful to perform formal EBM attending rounds. 相似文献
12.
Gita Ramjee Robin Shattock Sinead Delany Ian McGowan Neetha Morar Megan Gottemoeller 《AIDS research and therapy》2006,3(1):25-10
Current HIV/AIDS statistics show that women account for almost 60% of HIV infections in Sub-Saharan Africa. HIV prevention
tools such as male and female condoms, abstinence and monogamy are not always feasible options for women due to various socio-economic
and cultural factors. Microbicides are products designed to be inserted in the vagina or rectum prior to sex to prevent HIV
acquisition. 相似文献
13.
14.
Johanna L. Schmidt MPH MGC CGC Amy Pizzino MS CGC Jessica Nicholl MS CGC Allison Foley MMSc CGC Yue Wang PhD FACMG Jill A. Rosenfeld MS CGC Lindsey Mighion MS CGC Lora Bean PhD Cristina da Silva MS Megan T. Cho MS CGC Rebecca Truty PhD John Garcia PhD Virginia Speare PhD Kirsten Blanco BS Zoe Powis MS CGC Grace M. Hobson PhD Susan Kirwin BS Bryan Krock PhD FACMG Hane Lee PhD Joshua L. Deignan PhD Maggie A. Westemeyer MS CGC Ryan L. Subaran PhD Isabelle Thiffault PhD FABMGG Ellen A. Tsai PhD Terry Fang PhD Guy Helman BS Adeline Vanderver MD 《American journal of medical genetics. Part A》2020,182(8):1906-1912
Leukodystrophies are a heterogeneous group of heritable disorders characterized by abnormal brain white matter signal on magnetic resonance imaging (MRI) and primary involvement of the cellular components of myelin. Previous estimates suggest the incidence of leukodystrophies as a whole to be 1 in 7,000 individuals, however the frequency of specific diagnoses relative to others has not been described. Next generation sequencing approaches offer the opportunity to redefine our understanding of the relative frequency of different leukodystrophies. We assessed the relative frequency of all 30 leukodystrophies (associated with 55 genes) in more than 49,000 exomes. We identified a relatively high frequency of disorders previously thought of as very rare, including Aicardi Goutières Syndrome, TUBB4A‐related leukodystrophy, Peroxisomal biogenesis disorders, POLR3‐related Leukodystrophy, Vanishing White Matter, and Pelizaeus‐Merzbacher Disease. Despite the relative frequency of these conditions, carrier‐screening laboratories regularly test only 20 of the 55 leukodystrophy‐related genes, and do not test at all, or test only one or a few, genes for some of the higher frequency disorders. Relative frequency of leukodystrophies previously considered very rare suggests these disorders may benefit from expanded carrier screening. 相似文献
15.
16.
Villamor E Saathoff E Msamanga G O'Brien ME Manji K Fawzi WW 《Journal of acquired immune deficiency syndromes (1999)》2005,38(5):622-626
OBJECTIVES: To examine whether wasting during pregnancy, as measured by weight loss and low weight gain, is associated with increased mother-to-child transmission (MTCT) of HIV-1. METHODS: This was a cohort study in Dar es Salaam, Tanzania, among 957 HIV-1-infected pregnant women. Weight was measured at the first prenatal visit and every month thereafter until delivery. Weight loss was defined as a weekly rate of weight gain =0 and low weight gain as a weekly rate >0 and =166 g/wk. The incidences of presumptive intrauterine transmission (HIV status at birth) and presumptive intrapartum and early breast-feeding transmission (HIV status at 6 weeks) were examined in relation to baseline anthropometric characteristics and weight change during pregnancy using 2xn tables and multivariable binomial regression. RESULTS: Compared with women who gained >/=167 g/wk, weight loss during pregnancy was related to higher risk of intrauterine MTCT (adjusted relative risk [RR] = 2.32, 95% CI = 1.23-4.36, P = 0.009), HIV positive at birth or fetal death (RR = 2.13, 95% CI = 1.40-3.24, P = 0.0004), and HIV positive at birth or early neonatal death (RR = 1.96, 95% CI = 1.26-3.07, P = 0.003). The rate of weight gain during the 3rd trimester was inversely related to the risk of intrapartum/early breast-feeding transmission (adjusted P value, test for trend = 0.05). CONCLUSIONS: Weight loss during pregnancy increases the risk of early MTCT. Identifying causes of wasting during pregnancy may provide clues for new strategies to prevent MTCT. 相似文献
17.
Describing the Use of a Mindfulness-Based App for Sleep and Mental Well-Being,Across Age,in Children
Child & Youth Care Forum - In the United States, 68% of children do not get the recommended nine hours of sleep, which can lead to many negative health outcomes (e.g., mental health).... 相似文献
18.
Maldonado Linda Tina Ayala-Crespo Arleen Walsh Megan Marie Sheff Emily Karwacki Morris Gwendolyn 《Maternal and child health journal》2021,25(6):929-937
Maternal and Child Health Journal - The purpose of this study was to explore socio-ecological influences affecting the daily lives of urban, pregnant Puerto Rican women and factors negatively... 相似文献
19.
20.