全文获取类型
收费全文 | 7201篇 |
免费 | 460篇 |
国内免费 | 127篇 |
专业分类
耳鼻咽喉 | 88篇 |
儿科学 | 117篇 |
妇产科学 | 131篇 |
基础医学 | 736篇 |
口腔科学 | 292篇 |
临床医学 | 613篇 |
内科学 | 2243篇 |
皮肤病学 | 93篇 |
神经病学 | 613篇 |
特种医学 | 359篇 |
外科学 | 1173篇 |
综合类 | 36篇 |
一般理论 | 1篇 |
预防医学 | 279篇 |
眼科学 | 68篇 |
药学 | 350篇 |
中国医学 | 6篇 |
肿瘤学 | 590篇 |
出版年
2024年 | 15篇 |
2023年 | 137篇 |
2022年 | 261篇 |
2021年 | 471篇 |
2020年 | 275篇 |
2019年 | 312篇 |
2018年 | 349篇 |
2017年 | 244篇 |
2016年 | 289篇 |
2015年 | 300篇 |
2014年 | 388篇 |
2013年 | 432篇 |
2012年 | 610篇 |
2011年 | 533篇 |
2010年 | 301篇 |
2009年 | 301篇 |
2008年 | 399篇 |
2007年 | 373篇 |
2006年 | 331篇 |
2005年 | 277篇 |
2004年 | 209篇 |
2003年 | 179篇 |
2002年 | 139篇 |
2001年 | 48篇 |
2000年 | 35篇 |
1999年 | 36篇 |
1998年 | 49篇 |
1997年 | 39篇 |
1996年 | 38篇 |
1995年 | 24篇 |
1994年 | 37篇 |
1993年 | 28篇 |
1992年 | 13篇 |
1991年 | 15篇 |
1990年 | 15篇 |
1989年 | 36篇 |
1988年 | 28篇 |
1987年 | 24篇 |
1986年 | 15篇 |
1985年 | 23篇 |
1984年 | 9篇 |
1981年 | 14篇 |
1979年 | 12篇 |
1978年 | 14篇 |
1977年 | 14篇 |
1976年 | 10篇 |
1974年 | 13篇 |
1971年 | 8篇 |
1970年 | 8篇 |
1969年 | 7篇 |
排序方式: 共有7788条查询结果,搜索用时 15 毫秒
961.
Luigi Colì Gaetano La Manna Giorgia Comai Mauro Ursino Davide Ricci Matteo Piccari Francesco Locatelli Salvatore Di Filippo Luciano Cristinelli Massimo Bacchi Alessandro Balducci Filippo Aucella Vincenzo Panichi Francesco Paolo Ferrandello Renzo Tarchini Domenica Lambertini Carlo Mura Giancarlo Marinangeli Ermanno Di Loreto Francesco Quarello Giacomo Forneris Maurizio Tancredi Massimo Morosetti Giuditta Palombo Marina Di Luca Mauro Martello Giuseppe Emiliani Roberto Bellazzi Sergio Stefoni 《American journal of kidney diseases》2011,58(1):93-100
962.
Spinelli A Del Fabbro D Sacchi M Zerbi A Torzilli G Lutman FR Laghi L Malesci A Montorsi M 《World journal of surgery》2011,35(11):2521-2527
Background
The introduction of contrast-enhanced ultrasound has been a major innovation in liver and pancreatic imaging. Previous studies have validated its intraoperative use during liver surgery, while there is a lack of data regarding its use during pancreatic surgery. The purpose of the present study was to prospectively evaluate the possible role of contrast-enhanced intraoperative ultrasound (CEIOUS) during resective pancreatic surgery for primary lesion characterization and intraoperative staging. 相似文献963.
964.
Maria C Sorbo Luca Carioti Maria C Bellocchi FrancescoPaolo Antonucci Daniele Sforza Ilaria Lenci Matteo Ciancio Manuelli Daniele Armenia Francesco De Leonardis Martina Milana Tommaso M Manzia Mario Angelico Giuseppe Tisone Valeria Cento Carlo F Perno Francesca Ceccherini‐Silberstein 《Liver international》2019,39(10):1986-1998
965.
Matteo Serenari Giorgio Ercolani Alessandro Cucchetti Matteo Zanello Enrico Prosperi Guido Fallani Michele Masetti Raffaele Lombardi Matteo Cescon Elio Jovine 《Hepatobiliary & pancreatic diseases international : HBPD INT》2019,18(4):389-394
BackgroundBorderline resectable pancreatic cancer may require extended resections in order to achieve tumor-free margins, especially in the case of up-front resections, but it is important to know the limits of surgical therapy in this disease. This study aimed to investigate the impact of extent of pancreatic and venous resection on short- and long-term outcomes in patients with pancreatic adenocarcinoma (PDAC).MethodsThis was a retrospective study from a prospectively maintained database of pancreatic resections for PDAC. Short- and long-term outcomes were analyzed in patients having borderline resectable PDAC submitted to up-front total pancreatectomy (TP) or pancreaticoduodenectomy (PD) with simultaneous portal vein (PV) and/or superior mesenteric vein (SMV) resection. Venous resections were carried out as tangential venous resection (TVR) or segmental venous resection (SVR). Patients were divided into 4 groups: (1) PD + TVR, (2) PD + SVR, (3) TP + TVR, (4) TP + SVR. Uni- and multivariate Cox regression analysis were performed to identify factors associated with survival.ResultsNinety-nine patients were submitted to simultaneous pancreatic and venous resection for PDAC. Among them, 25 were submitted to PD + TVR (25.3%), 12 to PD + SVR (12.1%), 23 to TP + TVR (23.2%), and 39 to TP + SVR (39.4%). Overall, major morbidity (Clavien-Dindo grade ≥ IIIA) was 26.3%. Thirty- and 90-day mortality were 3% and 11.1%, respectively. There were no significant differences among groups in terms of short-term outcomes. Median overall survival of patients submitted to PD + TVR was significantly higher than those to TP+SVR (29.5 vs 7.9 months, P = 0.001). Multivariate analysis identified TP (HR = 2.11; 95% CI: 1.31–3.44; P = 0.002) and SVR (HR = 2.01; 95% CI: 1.27–3.15; P = 0.003) as the only independent prognostic factors for overall survival.ConclusionsUp-front TP associated to SVR was predictive of worse survival in borderline resectable PDAC. Perioperative treatments in high-risk surgical groups may improve such poor outcomes. 相似文献
966.
Gioel Gabrio Secco Achim Buettner Rosario Parisi Gianfranco Pistis Matteo Vercellino Andrea Audo Mashayekhi Kambis Roberto Garbo Italo Porto Giuseppe Tarantini Carlo Di Mario 《Cardiovascular Revascularization Medicine》2019,20(12):1083-1087
BackgroundCalcific coronary lesions can be so resistant to prevent symmetric stent dilatation with high risk of ISR/thrombosis. The aim of the current study is to evaluate the safety and efficacy of super high-pressure dilatation (>30-to-45Atm) using a dedicated NC-balloon (OPN, SIS-Medical-AG, Winterthur-Switzerland).MethodsWe retrospectively evaluated 326 consecutive undilatable lesions in which conventional NC-balloons failed to achieve adequate post-dilatation luminal gain. After the failed attempt an OPN-balloon was inflated up to achieve a uniform balloon expansion (maximal dilatation pressure of 45–50 Atm). Lesions were divided into two groups according to the final inflation pressure: Group-I: lesion responsive to 30-40Atm and Group-2:>40 Atm. Angiographic success was defined as residual angiographic stenosis<30% assessed by visual estimation with TIMI3-flow. Procedural success was defined as the achievement of angiographic success without any MACE.ResultsAngiographic success was achieved in 97.5%, procedural success in 96.6%; 53% of the lesions were responsive to a slower inflation pressure (Group I) while in the remaining 47%, the optimal expansion required a pressure > 40ATM (Group II). In 3 patients coronary rupture occurred after balloon inflation and was successfully treated with stent implantation with a final TIMI3-flow. The OPN alone was able to achieve adequate expansion in >90%. 0.9% days MACE were reported.ConclusionThe OPN-dedicated high-pressure balloon provides an effective and safe strategy for treatment of severe resistant coronary lesions. 相似文献
967.
Luca Barresi Matteo Tacelli Dario Ligresti Mario Traina Ilaria Tarantino 《Digestive and liver disease》2019,51(2):286-292
Despite the progress achieved by scientific research in recent years, pancreatic cystic lesions (PCLs) remain a challenging clinical problem. A significant percentage of benign PCLs are still wrongly sent to surgery, with all the related risks of a high number of surgery-related complications and mortality. Diagnosis of the type of PCL, and risk stratification for malignancy are essential for a correct management of these lesions. Several guidelines have identified some clinical and morphological aspects suggesting the need for more accurate exams. Endoscopic ultrasound fine needle aspiration (EUS-FNA) of cystic fluid for cytology is the advised method of tissue acquisition in several guidelines, and the most used technique around the world. However sensitivity and adequacy of this technique are limited by the low amount of cells dispersed in cystic fluid. Alternative techniques have been tested to target the cystic walls in an attempt to obtain microhistologic specimens in order to augment the probability of obtaining an adequate diagnostic sample.The aim of this review is to offer a critical overview of the existing literature on tissue acquisition in PCLs, and emphasize advantages and disadvantages of each technique, and unclear areas that need to be investigated with future research. 相似文献
968.
969.
970.