全文获取类型
收费全文 | 17623篇 |
免费 | 833篇 |
国内免费 | 102篇 |
专业分类
耳鼻咽喉 | 129篇 |
儿科学 | 397篇 |
妇产科学 | 184篇 |
基础医学 | 2328篇 |
口腔科学 | 323篇 |
临床医学 | 1135篇 |
内科学 | 4658篇 |
皮肤病学 | 191篇 |
神经病学 | 1250篇 |
特种医学 | 698篇 |
外科学 | 3294篇 |
综合类 | 41篇 |
预防医学 | 448篇 |
眼科学 | 329篇 |
药学 | 1436篇 |
中国医学 | 48篇 |
肿瘤学 | 1669篇 |
出版年
2023年 | 98篇 |
2022年 | 212篇 |
2021年 | 327篇 |
2020年 | 188篇 |
2019年 | 258篇 |
2018年 | 351篇 |
2017年 | 271篇 |
2016年 | 295篇 |
2015年 | 359篇 |
2014年 | 424篇 |
2013年 | 535篇 |
2012年 | 838篇 |
2011年 | 983篇 |
2010年 | 539篇 |
2009年 | 461篇 |
2008年 | 860篇 |
2007年 | 928篇 |
2006年 | 906篇 |
2005年 | 911篇 |
2004年 | 900篇 |
2003年 | 891篇 |
2002年 | 890篇 |
2001年 | 395篇 |
2000年 | 436篇 |
1999年 | 440篇 |
1998年 | 223篇 |
1997年 | 179篇 |
1996年 | 170篇 |
1995年 | 148篇 |
1994年 | 141篇 |
1993年 | 150篇 |
1992年 | 375篇 |
1991年 | 346篇 |
1990年 | 317篇 |
1989年 | 347篇 |
1988年 | 310篇 |
1987年 | 274篇 |
1986年 | 267篇 |
1985年 | 261篇 |
1984年 | 162篇 |
1983年 | 139篇 |
1982年 | 75篇 |
1981年 | 54篇 |
1979年 | 131篇 |
1978年 | 101篇 |
1977年 | 59篇 |
1975年 | 67篇 |
1974年 | 61篇 |
1973年 | 55篇 |
1969年 | 56篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
41.
42.
43.
Tsunao Imamura Rie Takeshita Rikako Koyama Chikao Okuda Kazuo Takeuchi Masamichi Matsuda Masashi Hashimoto Goro Watanabe Hitoshi Yoshida Michio Imawari 《Digestive endoscopy》2006,18(4):303-307
Background: Pancreatic carcinoma is one of the most lethal cancers. Because pancreatic carcinoma is still very difficult to diagnose in its early stage, many of these patients will be considered unsuitable for surgery. If a cytological diagnosis is obtained at initial endoscopic retrograde cholangiopancreatography (ERCP), suitable treatment will be initiated without delay. Methods: To increase the number of exfoliated cells from the pancreatic duct, we devised a new technique, pancreatic duct lavage fluid (PDLF), following bronchoalveolar lavage fluid. The present paper reports the effectiveness of cytological examination using PDLF in the diagnosis of pancreatic carcinoma. We examined 18 pancreatic carcinoma cases. After the endoscopic retrograde pancreatography (ERP), PDLF was collected from a double‐lumen catheter inserted into the main pancreatic duct. Saline injected from the lumen for the injection, and PDLF was aspirated from the other lumen for the guidewire at the same time. The cytological examination was performed using PDLF. Results: Exfoliated cells were more frequently found in PDLF from all patients. In 15 cases (83%), cytological examination of PDLF revealed positive cytological results as the diagnosis of pancreatic carcinoma. Conclusion: Cytological examination using PDLF has a high sensitivity for detection of pancreatic carcinoma. The new examination, PDLF, is simple, safe and effective, so we expect PDLF to become widely popular. 相似文献
44.
Mayumi Ujihara Sumiko Hamanaka Sachie Matsuda Fumitaka Numa Hiroshi Kato 《The Journal of dermatology》1994,21(1):56-58
A 76-year-old female was admitted with many bullae and erythema on her trunk and extremities. A biopsy specimen showed significant intercellular edema in the lower epidermis and eosinophilic infiltration into the dermis and the epidermis. Immunofluorescent staining revealed the deposition of IgG in the intercellular area of her prickle cells. From these histologic findings and the typical clinical features, we diagnosed her as having pemphigus vulgaris. Examination of her blood revealed that she also suffered from autoimmune hemolytic anemia. Despite intensive treatment with prednisolone, she finally died. This case is of interest because of its rarity and the TNFα detected significantly in the blister fluid of this patient. 相似文献
45.
K Matsuda N Tamura A Iwakura 《Kyobu geka. The Japanese journal of thoracic surgery》1992,45(10):883-885
A 62-year-old woman underwent primary anastomosis for dissecting aortic aneurysm (DeBakey IIIb) using GRF glue. GRF glue consists of mixture of gelatin and resorcin. The mixture is hardened by the addition of medical formaldehyde. Resorcin is diphenole which reacts with formaldehyde, creating tridimentional network. Primary anastomoses were performed after the lumen of dissected aorta was adhered with GRF glue. It appears that primary anastomosis using GRF glue is a simpler and safer operative method for dissecting aortic aneurysm. 相似文献
46.
47.
K Miyamoto Y Kawashima H Matsuda A Okuda S Maeda H Hirose 《The Journal of thoracic and cardiovascular surgery》1986,92(6):1065-1070
The relationship between the perfusion flow rate and cerebral oxygen consumption during deep hypothermic cardiopulmonary bypass at 20 degrees C was investigated in dogs. In 10 dogs the perfusion flow rate was decreased in steps from 100 to 60, 30, and 15 ml/kg/min every 30 minutes. Although cerebral blood flow decreased as perfusion flow rate decreased, the ratio of cerebral blood flow to the perfusion flow rate increased significantly (p less than 0.05) at a perfusion flow rate of 15 ml/kg/min compared to that at a perfusion flow rate of 100 or 60 ml/kg/min. The arterial-sagittal sinus blood oxygen content difference increased as perfusion flow rate decreased. Consequently, cerebral oxygen consumption did not vary significantly at perfusion flow rates of 100 (0.48 +/- 0.10), 60 (0.43 +/- 0.14), and 30 ml/kg/min (0.44 +/- 0.12 ml/100 gm/min), and it decreased significantly to 0.31 +/- 0.22 ml/100 gm/min at a perfusion flow rate of 15 ml/kg/min. In five dogs the perfusion flow rate was decreased in one step from 100 to 15 ml/kg/min, and after 60 minutes' perfusion at a perfusion flow rate of 15 ml/kg/min, the perfusion flow rate was returned to 100 ml/kg/min. Cerebral oxygen consumption decreased significantly during 60 minutes' perfusion at a perfusion flow rate of 15 ml/kg/min and did not return to its initial value after the perfusion flow rate was returned to 100 ml/kg/min. These data indicate that the optimal perfusion flow rate for the brain during deep hypothermic cardiopulmonary bypass at 20 degrees C appears to be 30 ml/kg/min, with a possible oxygen debt in the brain resulting in anaerobic metabolism if the perfusion flow rate is kept at 15 ml/kg/min or less. 相似文献
48.
The effect of dietary fiber on the induction of cytochrome P450IA1 in rat colonic mucosa after a single intragastric injection of 3-methylcholanthrene (3MC, 20 mg/kg) was investigated by examining the drug-metabolizing enzyme activity, immunoblotting for cytochrome P450IA1 and immunohistochemistry. 7-Ethoxycoumarin-O-deethylase activities were approximately 20-fold higher in microsomes from both proximal and distal portions of the colonic mucosa of control diet-fed 3MC-treated rats compared with those of control diet-fed untreated rats. Strong immunofluorescence for cytochrome P450IA1 was localized in the cytoplasm of the colonic mucosa surface epithelium from the control diet-fed 3MC-treated rats. 7-Ethoxycoumarin-O-deethylase activity and cytochrome P450IA1 content determined by immunoblotting were significantly lower in wheat bran-fed 3MC-treated rats than in control diet-fed 3MC-treated rats. Immunohistochemical analysis showed much weaker immunofluorescence for cytochrome P450IA1 in the surface epithelium of the colonic mucosa of the wheat bran-fed 3MC-treated rats. These observations suggested that dietary fiber can affect the induction of cytochrome P450IA1 in colonic mucosa by dietary inducers or carcinogens. 相似文献
49.
Maroun Dick M.D. Tulio E. Bertorini M.D. Masanori Igarashi M.D. 《Developmental medicine and child neurology》1992,34(3):262-265
Respiratory failure is an unusual initial manifestation of congenital muscular dystrophy. The authors describe a case of congenital muscular dystrophy in a patient presenting with rhabdomyolysis at birth. Despite an initially poor prognosis, aggressive respiratory therapy during the neonatal period permitted normal subsequent development. The muscular dystrophy predominantly involved the respiratory muscles. 相似文献
50.