全文获取类型
收费全文 | 34842篇 |
免费 | 2030篇 |
国内免费 | 273篇 |
专业分类
耳鼻咽喉 | 451篇 |
儿科学 | 626篇 |
妇产科学 | 544篇 |
基础医学 | 4233篇 |
口腔科学 | 1586篇 |
临床医学 | 2844篇 |
内科学 | 9261篇 |
皮肤病学 | 413篇 |
神经病学 | 3484篇 |
特种医学 | 1343篇 |
外科学 | 5593篇 |
综合类 | 99篇 |
一般理论 | 6篇 |
预防医学 | 1511篇 |
眼科学 | 555篇 |
药学 | 1872篇 |
中国医学 | 74篇 |
肿瘤学 | 2650篇 |
出版年
2024年 | 32篇 |
2023年 | 373篇 |
2022年 | 685篇 |
2021年 | 1282篇 |
2020年 | 764篇 |
2019年 | 1050篇 |
2018年 | 1268篇 |
2017年 | 997篇 |
2016年 | 1092篇 |
2015年 | 1163篇 |
2014年 | 1511篇 |
2013年 | 1846篇 |
2012年 | 2884篇 |
2011年 | 2773篇 |
2010年 | 1563篇 |
2009年 | 1417篇 |
2008年 | 2233篇 |
2007年 | 2341篇 |
2006年 | 2114篇 |
2005年 | 1937篇 |
2004年 | 1709篇 |
2003年 | 1564篇 |
2002年 | 1362篇 |
2001年 | 313篇 |
2000年 | 294篇 |
1999年 | 292篇 |
1998年 | 253篇 |
1997年 | 212篇 |
1996年 | 162篇 |
1995年 | 149篇 |
1994年 | 134篇 |
1993年 | 110篇 |
1992年 | 144篇 |
1991年 | 125篇 |
1990年 | 100篇 |
1989年 | 83篇 |
1988年 | 97篇 |
1987年 | 70篇 |
1986年 | 56篇 |
1985年 | 65篇 |
1984年 | 55篇 |
1983年 | 45篇 |
1982年 | 47篇 |
1981年 | 29篇 |
1980年 | 26篇 |
1979年 | 43篇 |
1978年 | 32篇 |
1977年 | 25篇 |
1973年 | 33篇 |
1972年 | 30篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
21.
Angelo M. Carella Sandro Nati Paolo Carlier Daniela Pierluigi Domenico Giordano Angela Congiu Gino Santini Daniele Scarpati Salvina Barra Renzo Corvo Vito Vitale Maria R. Raffo Raffaella Cerri Marco Risso Mauro Spriano Renato Vimercati Ester Pungolino Andrea Bacigalupo Eugenio Damasio 《Leukemia & lymphoma》1991,5(1):43-47
Forty consecutive adult patients under the age of 50 with acute non-lymphoblastic leukemia (ANLL) in first complete remission, underwent autologous bone marrow transplantation (ABMT) between March 1984 and April 1990. The conditioning regimen employed included cyclophosphamide and total body irradiation, followed by the administration of unpurged ABMT. The median time from diagnosis to transplant was 7 months (3-15 months), and the median time from complete remission to ABMT was 4 months (range 3-9 months). Twenty-two (51%) patients remain in complete remission 6-81 months (median 24 months) after ABMT.
The causes of death were, recurrent leukemia (11 patients), parenchymal toxicities such as acute respiratory distress syndrome and veno-occlusive disease (3 patients), hemorrhage (2 patients) and infection (2 patients). Eleven patients relapsed after 3-12 months (median 5 months). This study has produced survival data comparable to those of other institutions employing TBI for either allo or autotransplants. 相似文献
The causes of death were, recurrent leukemia (11 patients), parenchymal toxicities such as acute respiratory distress syndrome and veno-occlusive disease (3 patients), hemorrhage (2 patients) and infection (2 patients). Eleven patients relapsed after 3-12 months (median 5 months). This study has produced survival data comparable to those of other institutions employing TBI for either allo or autotransplants. 相似文献
22.
Francesco Landi Ettore Capoluongo Andrea Russo Graziano Onder Matteo Cesari Paola Lulli Angelo Minucci Marco Pahor Cecilia Zuppi Roberto Bernabei 《Growth hormone & IGF research》2007,17(1):58-66
CONTEXT: Increasing evidences from experimental and human studies suggest that the activity of the growth hormone (GH/insulin-like growth factor-I) axis may contribute to the age-related cognitive decline and poor cognition in late life. OBJECTIVE: The aim of the present study was to evaluate the relationship of total serum free IGF-I and its binding protein-3 with cognitive performance in older persons aged 80 years or older. DESIGN: Data are from baseline evaluation of the ilSIRENTE study (n=353). Cognitive performance was evaluated using five items enclosed in the Minimum Data Set for Home Care assessment form: short-term memory, procedural memory, cognitive skills in daily decision making, verbal expression, comprehension. Free insulin-like growth factor-I (free IGF-I) and IGF-binding protein-3 (IGFBP-3) in blood were measured. Analysis of covariance (ANCOVA) was used to examine the relationship between cognitive impairment and the serum free IGF-I and IGFBP-3 concentrations, after adjustment for potential confounding variables. RESULTS: After adjustment for potential confounders, which included age, gender, education, cerebrovascular disease, ischemic heart disease, congestive heart failure, hypertension, diabetes, depression, Parkinson diseases, thyroid diseases, smoking status, alcohol abuse, body mass index, and number of medications, individuals with verbal expression problems (n=20) and individuals with comprehension problems (n=24) had a significantly lower serum levels of readily dissociable IGF-I than participants without cognitive impairments. The serum IGFBP-3 presented the same behavior of free IGF-I. CONCLUSION: The present study suggests that among old-old subjects living in the community lower levels of total serum free IGF-I and IGFBP-3 are associated with impairment of cognitive performance. This finding suggests that the GH/IGF-I axis may play an important role in the age-related decline of cognitive performance. 相似文献
23.
24.
25.
Dario Roccatello Marco Formica Guido Cavalli Maria C. Amprimo Maria G. Pignatelli Paolo Costa Ruggero de Paulis Giacomo Quattrocchio rea Molino Gianbeppe Giordano 《Artificial organs》1990,14(1):69-72
Neutrophil oxidative metabolism, C3d and beta 2 microglobulin levels, were assessed in nine consecutive patients undergoing cardiopulmonary bypass surgery with polypropylene hollow fiber oxygenators for open cardiac operations. Generation of oxygen free radicals by neutrophils was measured as luminol-enhanced chemiluminescence after stimulation with opsonized Zymosan and phorbol myristate acetate. A significant increase in light emission was detected by using both of the chemiluminescence stimulators. Moreover, a remarkable and significant increase in C3d levels was found already at 10 min. Conversely minimal changes in levels of beta 2 microglobulin were detected during cardiopulmonary bypass surgery. These data suggest that the impact of the patient blood with the foreign surface of cardiopulmonary bypass results in activation of phagocyte cells with increased potential in oxygen consumption. These effects could be partially complement-mediated. 相似文献
26.
Current controversies in oral lichen planus: report of an international consensus meeting. Part 1. Viral infections and etiopathogenesis. 总被引:11,自引:0,他引:11
Giovanni Lodi Crispian Scully Marco Carrozzo Mark Griffiths Philip B Sugerman Kobkan Thongprasom 《Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics》2005,100(1):40-51
Despite recent advances in understanding the immunopathogenesis of oral lichen planus (LP), the initial triggers of lesion formation and the essential pathogenic pathways are unknown. It is therefore not surprising that the clinical management of oral LP poses considerable difficulties to the dermatologist and the oral physician. A consensus meeting was held in France in March 2003 to discuss the most controversial aspects of oral LP. Part 1 of the meeting report focuses on (1) the relationship between oral LP and viral infection with special emphasis on hepatitis C virus (HCV), and (2) oral LP pathogenesis, in particular the immune mechanisms resulting in lymphocyte infiltration and keratinocyte apoptosis. Part 2 focuses on patient management and therapeutic approaches and includes discussion on malignant transformation of oral LP. 相似文献
27.
Roberto Marco 《Developmental dynamics》2006,235(4):855-860
In this review article, we shall focus our attention on the initial steps in the research career of José A. Campos-Ortega and the studies he undertook. Particular emphasis will be placed on how these early experiences shaped his personality and his future scientific contributions. 相似文献
28.
29.
30.
Papillary thyroid microcarcinomas (PTMs) are small tumors (< or =1 cm of diameter) that belong to the well-differentiated low-risk carcinomas of the thyroid, which are characterized by benign behavior, probably of little clinical significance, and do not affect patients' survival. They are found in otherwise normal thyroids or in multinodular goiters with a clinical frequency varying substantially according to different series. Sometimes, PTM may be associated with lymph node metastases at presentation and/or locoregional recurrences during follow-up. Distant metastases are extremely rare, but have been reported. Although deaths related to PTM are almost unknown, PTM raises therapeutic implications. This review addresses the issue of definition, treatment, and follow-up of PTM. 相似文献