全文获取类型
收费全文 | 185672篇 |
免费 | 53047篇 |
国内免费 | 7028篇 |
专业分类
耳鼻咽喉 | 2605篇 |
儿科学 | 5760篇 |
妇产科学 | 2908篇 |
基础医学 | 28598篇 |
口腔科学 | 7179篇 |
临床医学 | 27414篇 |
内科学 | 40009篇 |
皮肤病学 | 8346篇 |
神经病学 | 19053篇 |
特种医学 | 6052篇 |
外国民族医学 | 47篇 |
外科学 | 25508篇 |
综合类 | 16965篇 |
现状与发展 | 25篇 |
一般理论 | 42篇 |
预防医学 | 10784篇 |
眼科学 | 4429篇 |
药学 | 17109篇 |
57篇 | |
中国医学 | 6418篇 |
肿瘤学 | 16439篇 |
出版年
2024年 | 276篇 |
2023年 | 1520篇 |
2022年 | 3676篇 |
2021年 | 6724篇 |
2020年 | 8807篇 |
2019年 | 14053篇 |
2018年 | 13681篇 |
2017年 | 14382篇 |
2016年 | 14914篇 |
2015年 | 16469篇 |
2014年 | 17676篇 |
2013年 | 17428篇 |
2012年 | 12185篇 |
2011年 | 12983篇 |
2010年 | 14163篇 |
2009年 | 9318篇 |
2008年 | 7774篇 |
2007年 | 6877篇 |
2006年 | 6748篇 |
2005年 | 6856篇 |
2004年 | 4894篇 |
2003年 | 4467篇 |
2002年 | 4103篇 |
2001年 | 3552篇 |
2000年 | 3667篇 |
1999年 | 3281篇 |
1998年 | 1846篇 |
1997年 | 1712篇 |
1996年 | 1471篇 |
1995年 | 1333篇 |
1994年 | 1092篇 |
1993年 | 723篇 |
1992年 | 1134篇 |
1991年 | 901篇 |
1990年 | 797篇 |
1989年 | 682篇 |
1988年 | 670篇 |
1987年 | 591篇 |
1986年 | 488篇 |
1985年 | 380篇 |
1984年 | 252篇 |
1983年 | 176篇 |
1982年 | 104篇 |
1981年 | 115篇 |
1980年 | 96篇 |
1979年 | 127篇 |
1978年 | 64篇 |
1977年 | 60篇 |
1975年 | 56篇 |
1974年 | 55篇 |
排序方式: 共有10000条查询结果,搜索用时 250 毫秒
111.
112.
113.
T.-Y. Huang Y.-J. Hsia M.-Y. Sung Y.-T. Wu P.-C. Hsu 《International journal of oral and maxillofacial surgery》2021,50(8):1100-1106
Zygomatic implant treatment is widely applied for severe maxillary atrophy to help rehabilitate the maxillary dentition. This retrospective study was performed to evaluate the actual radiographic bone–implant contact (rBIC) lengths of zygomatic implants. The records of 28 patients who underwent zygomatic implant surgery and subsequent follow-up examinations between August 2013 and September 2018 in the Department of Oral and Maxillofacial Surgery, Taipei Tzu Chi Hospital were reviewed. The surgeries were performed by a single surgeon using the same treatment protocol. All patients had a computed tomography scan at 1 year after the surgery. Using three-dimensional imaging software, an investigator measured the rBIC lengths of 66 implants and documented their clinical status. The implant survival rate was 100%. The mean rBIC length was significantly longer in male patients than in female patients (20.80 ± 5.88 mm versus 17.79 ± 6.34 mm; P = 0.028). The mean rBIC length of double zygomatic implants was significantly longer when compared to that of single implants (21.11 ± 6.23 mm versus 17.75 ± 5.85 mm; P = 0.027). This article is novel in reporting the exact rBIC lengths of zygomatic implants in a clinical setting. The results showed that zygomatic implants are a viable treatment modality for full-mouth rehabilitation. 相似文献
114.
115.
116.
117.
Tuberculosis (TB) remains one of a major health problem worldwide. Tuberculosis vaccine research has made an extraordinary progress over the past few years. However, there is still no replacement for the Bacillus Calmette‐Guérin vaccine, the only TB vaccine licensed for human use. Therefore, the discovery and development of new TB vaccines remains a priority. This article discusses current strategies used to diversify TB vaccines and includes discussion of the status of efforts to improve protection against Mycobacterium tuberculosis (M tb) infection or TB disease by developing new and safe TB vaccines. This article also highlights the current research efforts in immune‐enhancing approaches to improve vaccination efficacy. The development of more effective TB vaccines might have significant impact on global TB control. 相似文献
118.
Erika Cecon Anna Ivanova Marine Luka Florence Gbahou Anne Friederich Jean‐Luc Guillaume Patrick Keller Klaus Knoch Raise Ahmad Philippe Delagrange Michele Solimena Ralf Jockers 《Journal of pineal research》2019,66(2)
Melatonin receptors play important roles in the regulation of circadian and seasonal rhythms, sleep, retinal functions, the immune system, depression, and type 2 diabetes development. Melatonin receptors are approved drug targets for insomnia, non‐24‐hour sleep‐wake disorders, and major depressive disorders. In mammals, two melatonin receptors (MTRs) exist, MT1 and MT2, belonging to the G protein‐coupled receptor (GPCR) superfamily. Similar to most other GPCRs, reliable antibodies recognizing melatonin receptors proved to be difficult to obtain. Here, we describe the development of the first monoclonal antibodies (mABs) for mouse MT1 and MT2. Purified antibodies were extensively characterized for specific reactivity with mouse, rat, and human MT1 and MT2 by Western blot, immunoprecipitation, immunofluorescence, and proximity ligation assay. Several mABs were specific for either mouse MT1 or MT2. None of the mABs cross‐reacted with rat MTRs, and some were able to react with human MTRs. The specificity of the selected mABs was validated by immunofluorescence microscopy in three established locations (retina, suprachiasmatic nuclei, pituitary gland) for MTR expression in mice using MTR‐KO mice as control. MT2 expression was not detected in mouse insulinoma MIN6 cells or pancreatic beta‐cells. Collectively, we report the first monoclonal antibodies recognizing recombinant and native mouse melatonin receptors that will be valuable tools for future studies. 相似文献
119.
我国奶牛养殖规模不断扩大,奶业产值比重逐步提高,给奶牛疫病防治带来巨大压力。奶牛乳房炎及细菌性肺炎等呼吸系统疾病和细菌性肠炎等消化系统疾病最为常见,抗菌药物的使用成为主要防治手段。但抗菌药物的不当使用易使细菌产生耐药性,增加临床治疗的成本和难度,危害我国奶牛产业发展。本文对截至2021年7月我国和美国、英国、日本、欧盟批准用于奶牛的抗菌药物产品进行整理、统计与分析,包括抗菌药物的分类、剂型以及适应证等,旨在为我国奶牛用抗菌药物管理、合理用药和新兽药开发提供参考。 相似文献
120.