全文获取类型
收费全文 | 5469篇 |
免费 | 275篇 |
国内免费 | 126篇 |
专业分类
耳鼻咽喉 | 270篇 |
儿科学 | 113篇 |
妇产科学 | 113篇 |
基础医学 | 778篇 |
口腔科学 | 50篇 |
临床医学 | 619篇 |
内科学 | 869篇 |
皮肤病学 | 112篇 |
神经病学 | 839篇 |
特种医学 | 291篇 |
外国民族医学 | 1篇 |
外科学 | 782篇 |
综合类 | 72篇 |
预防医学 | 265篇 |
眼科学 | 169篇 |
药学 | 341篇 |
中国医学 | 22篇 |
肿瘤学 | 164篇 |
出版年
2023年 | 25篇 |
2022年 | 32篇 |
2021年 | 91篇 |
2020年 | 53篇 |
2019年 | 74篇 |
2018年 | 78篇 |
2017年 | 71篇 |
2016年 | 101篇 |
2015年 | 125篇 |
2014年 | 162篇 |
2013年 | 214篇 |
2012年 | 288篇 |
2011年 | 272篇 |
2010年 | 195篇 |
2009年 | 211篇 |
2008年 | 244篇 |
2007年 | 324篇 |
2006年 | 269篇 |
2005年 | 259篇 |
2004年 | 238篇 |
2003年 | 202篇 |
2002年 | 203篇 |
2001年 | 180篇 |
2000年 | 188篇 |
1999年 | 163篇 |
1998年 | 100篇 |
1997年 | 90篇 |
1996年 | 72篇 |
1995年 | 68篇 |
1994年 | 68篇 |
1993年 | 46篇 |
1992年 | 100篇 |
1991年 | 109篇 |
1990年 | 91篇 |
1989年 | 85篇 |
1988年 | 81篇 |
1987年 | 67篇 |
1986年 | 59篇 |
1985年 | 47篇 |
1984年 | 40篇 |
1983年 | 34篇 |
1982年 | 20篇 |
1981年 | 19篇 |
1980年 | 21篇 |
1979年 | 21篇 |
1977年 | 19篇 |
1975年 | 17篇 |
1974年 | 28篇 |
1973年 | 20篇 |
1972年 | 20篇 |
排序方式: 共有5870条查询结果,搜索用时 15 毫秒
31.
Dr. J. Harder K. Thürmel M. Maier I. Lanzl 《Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft》2009,106(10):924-927
A 41-year-old male patient presented with veiled vision which had appeared only a few hours previously. Funduscopy revealed a retinal edema due to venous stasis retinopathy. A previous history was unknown except for an uncorrected arterial hypertension. A retinal vein thrombosis and macula edema developed in the affected eye. An antiphospholipid antibody syndrome was diagnosed which was treated with anticoagulants. 相似文献
32.
33.
Judith A. Maloni RN PhD Ching-Yu Cheng RN MSN Cary P. Liebl RNC BSN Jeanmarie Sharp Maier RN BSN 《Journal of obstetric, gynecologic, and neonatal nursing : JOGNN / NAACOG》1996,25(1):17-23
The current model for delivery of prenatal care was developed more than 100 years ago. Evidence suggests that this model is no longer appropriate for meeting national health objectives or for meeting the needs of a diverse population of pregnant women. This article provides a historical overview of prenatal care; describes the current system for care delivery and problems associated with it; and suggests strategies for transforming care into an effective, comprehensive model. JOGNN, 25, 17–23; 1996. 相似文献
34.
H. W. Gottfried S. Maier E. Brändle K. Kleinschmidt R. Hautmann 《Der Urologe. Ausg. A》1997,36(5):413-419
Summary
Minimally invasive treatment of urinary incontinence has become a subject of major interest in recent years. We examined the
use of transurethral collagen injection for incontinence treatment. A total of 48 patients were selectet for this procedure
from April 1993 to February 1997 – 26 male patients (19 post-RPX incontinence and 7 post-TUR incontinence) and 22 female patients
(all after previous incontinence surgery) were treated by injection of collagen into the continence region. The whole group
underwent an average of 1.8 sessions, and a mean collagen injection volume of 14.5 ml was delivered per session. Mean follow-up
was 9.2 months. Of the female population, 68.2 % were cured or greatly improved. In the male population only 47.3 % of the
post-RPX patients and 6/7 of the post-TUR patients benefited from the procedure. In males, treatment outcome depends on the
degree of pretreatment incontinence, because all grade III incontinence patients did worse. Therefore we conclude: transurethral
collagen injection is an interesting method in the treatment of urinary incontinence if proper patient selection is assured.
相似文献
35.
BACKGROUND: Autoantibody production by the fetus is thought to be extremely unlikely. Only one possible case of in utero autoantibody production against red cells by the fetus has previously been described. STUDY DESIGN AND METHODS: A case of apparent red cell IgG autoantibody production in utero is reported. RESULTS: This was established by a positive direct antiglobulin test in a newborn infant without evidence of maternal alloantibodies or autoantibodies. There was no evidence of clinically significant hemolysis at the infant's birth. After 6 weeks, his direct antiglobulin test remained strongly positive. The infant thrived without evidence of hemolysis, and after 6 months the direct antiglobulin test was negative. CONCLUSION: The production of autoantibodies to red cells in utero is possible, though rare. This did not result in apparent hemolysis in this patient. 相似文献
36.
Stephan E Maier Sridhar Vajapeyam Hatsuho Mamata Carl-Fredrik Westin Ferenc A Jolesz Robert V Mulkern 《Magnetic resonance in medicine》2004,51(2):321-330
Several studies have shown that in tissues over an extended range of b-factors, the signal decay deviates significantly from the basic monoexponential model. The true nature of this departure has to date not been identified. For the current study, line scan diffusion images of brain suitable for biexponential diffusion tensor analysis were acquired in normal subjects on a clinical MR system. For each of six noncollinear directions, 32 images with b-factors ranging from 5 to 5000 s/mm2 were collected. Biexponential fits yielded parameter maps for a fast and a slow diffusion component. A subset of the diffusion data, consisting of the images obtained at the conventional range of b-factors between 5 and 972 s/mm2, was used for monoexponential diffusion tensor analysis. Fractional anisotropy (FA) of the fast-diffusion component and the monoexponential fit exhibited no significant difference. FA of the slow-diffusion biexponential component was significantly higher, particularly in areas of lower fiber density. The principal diffusion directions for the two biexponential components and the monoexponential solution were largely the same and in agreement with known fiber tracts. The second and third diffusion eigenvector directions also appeared to be aligned, but they exhibited significant deviations in localized areas. 相似文献
37.
S Schlegel W Maier M Philipp J B Aldenhoff I Heuser K Kretzschmar O Benkert 《Psychiatry research》1989,29(2):221-230
The relationship between psychopathology and brain alterations, measured by computed tomography (CT), was investigated in 44 depressed patients. Comparisons of ventricle-brain ratio (VBR) between "endogenous" vs. "nonendogenous" subgroups, classified by six distinct diagnostic systems, revealed no significant differences. The VBR and the width of the third ventricle correlated significantly with scores on the Brief Psychiatric Rating Scale, the Global Assessment Scale, the Bech-Rafaelsen Melancholia Scale, the Rating for Emotional Blunting, and the Scale for the Assessment of Negative Symptoms, but not with scores on the Hamilton Rating Scale for Depression and the Hamilton Rating Scale for Anxiety. Item analyses of the Bech-Rafaelsen Melancholia Scale revealed that retardation-related items were most significantly correlated with ventricular size. The wider diameter of the third ventricle in psychotic patients was associated with higher scores on retardation in the psychotic subgroup, whereas the greater distances of both Sylvian fissures showed no relationship to psychomotor retardation. No significant correlations were found between CT values and anxiety, suicidal impulses, somatic complaints, and sleep disturbances. 相似文献
38.
39.
Applications of a rat multiple tissue gene expression data set 总被引:4,自引:0,他引:4
Walker JR Su AI Self DW Hogenesch JB Lapp H Maier R Hoyer D Bilbe G 《Genome research》2004,14(4):742-749
With the sequencing and assembly of the rat genome comes the difficult task of assigning functions to genes. Tissue localization of gene expression gives some information about the potential role of a gene in physiology. Various examples of the utility of multiple tissue gene expression data sets are illustrated here. First, we highlight their use in finding genes that might play an important role in a particular tissue on the basis of exclusive expression in that tissue or coexpression with a gene or genes with known function. Second, we show how this data might be used to explain known phenotypic differences between strains. Third, we show how expression patterns of genes in a genomic interval might identify candidate genes in quantitative trait loci (QTL) mapping studies. Lastly, we show how multiple tissue and species data can help researchers prioritize follow up studies to microarray experiments. All of these applications of multiple tissue gene expression data sets will play a role in functionally annotating the rat genome. 相似文献
40.
Schwerer MJ Hemmer J Kraft K Maier H Möller P Barth TF 《Virchows Archiv : an international journal of pathology》2003,443(1):98-103
We report the case of a 58-year-old man who presented with a squamous cell carcinoma pT1a G2 of the left vocal cord. Six months after histologically verified complete resection, the patient experienced an endolaryngeal and extralaryngeal local recurrence pT4 pN2b G2. We applied DNA flow cytometry (FCM) and comparative genomic hybridization (CGH) on both primary and recurrent tumor. The primary tumor and the endolaryngeal compartment of the relapse was an aneuploid cell clone with a FCM DNA index of 1.42 and 1.44, respectively. The extralaryngeal compartment showed a shift featuring a DNA index of 2.78. In the primary tumor and in both compartments of the recurrence there was an identical pattern of complex chromosomal imbalances as detected in CGH (CGH karyotype: rev ish enh [8q24.2-q24.3, 10q26.1-q26.3, 11q24-q25, 12q24.2-q23.33,X], dim [4q, 13q14.3-q31], amp[1p36.1-p36.2]). Hence, the recurrence was not associated with further gains and losses of chromosomal material. However, in the anterior part of the recurrence, the aneuploid tumor cell genome had completely doubled, obviously due to endoreduplication. Immunohistochemical analysis of several cell-cycle regulators revealed altered expression of checkpoint proteins, pointing to a complex disturbance in cell-cycle regulation. 相似文献