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941.
Objective?To analyze the application effects of dezocine combined with butorphanol on postoperative analgesia, sedation and complications of puerperae with cesarean section. Methods?98 patients after cesarean section treated in the First Affiliated Hospital of Henan University of CM between October 2019 and March 2021 were selected, and randomly divided into control group (n=48, treated with butorphanol) and observation group (n=50, treated with dezocine combined with butorphanol). Visual Analogue Scale (VAS), Bruggrmann Comfort Scale (BCS) and Ramsay Sedation Score (RSS) were used to compare the analgesic effects at 1 h, 6 h, 12 h and 24 h after surgery (T1-T4). Levels of C-reactive protein (CRP), interleukin-6 (IL-6) and interleukin-2 (IL-2) of the two groups were compared at T1 and T4. Incidence rate of postoperative complications was compared between the two groups. Results?VAS scores of patients in observation group at T1-T4 were lower while BCS scores were higher compared those in control group, and Ramsay sedation scores at T1-T3 were higher than those in control group, with time-point effect, between-group effect and interaction effect (P<0.05). Levels of CRP and IL-6 of observation group at T1 and T4 were lower while level of IL-2 was higher compared to control group (P<0.05). The incidence rates of complications of the two groups were 8.00% and 16.67% respectively (P>0.05). Conclusion?Dezocine combined with butorphanol has better sedative and analgesic effects on puerperae after cesarean section, and it helps to improve the comfort and relieve the body’s inflammatory response, with few complications. 相似文献
942.
Ding Fang Lyu Yalin Han Xiao Zhang Hai Liu Dongyu Hei Wei Liu Yinhua 《中华医学杂志(英文版)》2014,127(23):4114-4118
Background The occurrence and development of aortic aneurysm (AA) are associated with infection.Some researchers have detected the DNA of periodontal pathogens in AA samples in certain populations.However,it has not been done in Chinese population.The objective of this study was to evaluate the prevalence of periodontal pathogens in oral tissue samples and aneurysm samples of AA patients.Methods Eighty-nine subjects with AA and 59 subjects without AA were examined.Periodontal clinical parameters were evaluated.Unstimulated saliva and subgingival plaque somples were collected from all subjects.Twenty-six dissected AA samples were obtained.Evidence of eight periodontal pathogens including Porphyromonas gingivalis (Pg),Actinobacillus actinomycetemcomitans (Aa),Prevotella intermedia (Pi),Tannerella forsythensis (Tf),Treponema denticola (Td),Campylobacter rectus (Cr),Fusobacterium nucleatum (Fn),and Prevotella nigrescens (Pn) was ascertained in all samples by 16S rRNA-based polymerase chain reaction (PCR) assay.Results The periodontal indexes including plaque index (PLI),probing depth (PD),bleeding index (BI),and clinical attachment loss (CAL),of the six Ramfjord index teeth were significantly higher in the AA group than those in the control group (P <0.01).Eight periodontal pathogens in subgingival plaque samples were more frequently detected in the AA group than in control group.The difference in prevalence between the groups was significant for six (out of eight) periodontal pathogens assayed (Pg,Pi,Fn,Pn,Tf,and Td,P <0.01).Additionally,all eight periodontal pathogens were more frequently detected in saliva samples of the AA group than in those of the control group,again with six (out of eight) (Pg,Pi,Fn,Cr,Tf,and Td) displaying significant differences in prevalence between the two groups (P <0.01).Out of 26 aneurysm samples examined,Pg,Pi,Fn,Crand Tfwere detected in 6 (23.1%),2 (7.7%),3 (11.5%),1 (3.8%),2 相似文献
943.
目的探讨彩色多普勒超声对下肢动脉支架内再狭窄(ISR)的诊断价值,为临床应用提供依据。方法选取下肢动脉支架植入术后12个月内,经CT血管造影(CTA)或数字减影血管造影(DSA)证实的再狭窄患者31例(植入支架再狭窄47处)、未狭窄患者63例(植入支架89处)及健康对照者30名行超声检查,获取支架内、支架近心端及远心端自体血管的二维超声声像图特点及收缩期峰值血流速度(PSV)、收缩期血流加速时间(AT),与健康对照者相应血管血流参数作比较。应用受试者操作特性(ROC)曲线分析PSV、AT对下肢动脉ISR的诊断价值。结果未狭窄组股总动脉、股浅动脉、腘动脉支架内PSV分别为(146.71±35.59)、(120.11±25.67)、(96.44±32.87)cm/s,健康对照组上述指标分别为(119.67±15.34)、(91.17±15.09)、(71.13±21.23)cm/s,组间比较,差异均有统计学意义(t=2.457、2.459、2.321,P均〈0.05);未狭窄组股总动脉、股浅动脉、腘动脉AT分别为(84.98±13.77)、(87.33±16.36)、(90.77±12.05)ms;健康对照组上述指标分别为(78.23±21.24)、(82.31±18.24)、(84.29±23.01)ms,组间比较,差异均无统计学意义(t=1.696、1.904、1.835,P均〉0.05)。再狭窄组支架近心端、狭窄处、远心端PSV分别为(87.67±23.34)、(218.17±72.09)、(54.13±21.23)cm/s,未狭窄组支架近心端、支架内、远心端PSV分别为(91.71±25.59)、(131.11±45.67)、(96.44±32.87)cm/s,组间比较,支架内/狭窄处及支架远心端PSV的差异有统计学意义(t=3.412、3.511,P均〈0.01),支架近心端PSV差异无统计学意义(t=1.901,P〉0.05);再狭窄组支架近心端、狭窄处、远心端AT分别为(98.31±14.09)、(109.54±21.03)、(158.23±45.21)ms,未狭窄组支架近心端、支架内、远心端AT分别为(84.98±13.77)、(86.34±19.36)、(83.77±17.05)ms,组间比较,支架内/狭? 相似文献
944.
Objective:The purpose of this study is to screen and evaluate cosmetic products for sensitive skin on the face.Methods:Thirty-five subjects with positive lactic acid sting test (LAST) were recruited from the staff of our hospital from November 2019 to February 2020. First, the human skin enclosed patch test of cosmetic gel (abbreviated as gel) was performed, and then the tested products were continuously applied for 4 weeks to complete the long-term efficacy test. Subjects’ sensation of application, pruritus, tingling and burning were assessed on a 0 to 9 scale prior to, 14, and 28 days after topical application. Moreover, the transepidermal water loss rate (TEWL), stratum corneum (SC) hydration, melanin index (MI), erythema index (EI) and dendritic cells and inflammatory cell infiltration were noninvasively detected by the tester. LAST were performed before applying, 14 and 28 days after application, and then the test results were compared.Results:In this study, a total of 34 people participated in the test. The results of human skin enclosed patch test indicated that only 1 case of grade 1 reaction occurred among the tested subjects. The subjects felt good after applying the products, and the gel showed high degree of skin comfortable, no irritation and good tolerability. Subjective safety evaluation illustrated that the scores of pruritus, tingling and burning of the subjects decreased in D14 and D28 patient revisit, showing statistically significant differences (P < .05). When the gel was applied for 4 weeks, TEWL (8.42 ± 1.12) and EI (201.35 ± 13.51) were lower than the results before application (P < .05), and the SC hydration (65.36 ± 2.56) was higher than that before application (P < .05). There was no correlation between the SC hydration and TEWL (R = 0.092, P = .416). The results of skin CT indicated that the number of facial dendritic cells decreased in 17 subjects (accounting for 50%) in D28 patient revisit, and the degree of inflammatory cell infiltration decreased in 27 subjects (accounting for 80%). Compared with the baseline value, the LAST score and total sensory score decreased after application the product for 4 weeks, and the difference was statistically significant (the mean value of P < .05).Conclusion:The subjective feeling of application and efficacy of cosmetics in people with sensitive skin could be successfully evaluated by the comprehensive application of human skin enclosed patch test, long-term trial test, subjective safety evaluation and objective efficacy evaluation. And it provides the basis to judge whether the cosmetic is consistent with the efficacy claim of sensitive skin. 相似文献
945.
Lei Yang Xiangji Ying Shuo Liu Guoqing Lyu Zekuan Xu Xi Zhang Huichao Li Qingyu Li Ning Wang Jiafu Ji 《中国癌症研究》2020,32(6):695-704
Gastric cancer(GC) is a global health problem, with more than 1 million people newly diagnosed with GC worldwide each year. GC is more prevalent in less developed countries than in more developed countries. About half of all GC cases worldwide occur in East Asia, notably China. Globally, overall incidence rates of GC are declining, which is potentially attributed to a decrease in Helicobacter pylori(H. pylori) infection and the use of refrigeration to preserve foods rather than salt. GC is a mul... 相似文献
946.
947.
948.
You Shang Jianfeng Wu Jinglun Liu Yun Long Jianfeng Xie Dong Zhang Bo Hu Yuan Zong Xuelian Liao Xiuling Shang Renyu Ding Kai Kang Jiao Liu Aijun Pan Yonghao Xu Changsong Wang Qianghong Xu Xijing Zhang Jicheng Zhang Ling Liu Jiancheng Zhang Yi Yang Kaijiang Yu Xiangdong Guan Dechang Chen 《中华医学杂志(英文版)》2022,135(16):1913
949.
950.