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91.
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93.
Ekemini D. Akpan Ibanga O. Isaac Lukman O. Olasunkanmi Eno E. Ebenso El-Sayed M. Sherif 《RSC advances》2019,9(51):29590
Electrochemical, surface morphology, density functional theory and Monte Carlo simulation methods were employed in investigating the effects of (2E,2′E)-2,2′-(3,3,6,6-tetramethyl-9-phenyl-3,4,6,7-tetrahydroacridine-1,8(2H,5H,9H,10H)-diylidene)bis(N-phenylhydrazinecarbothioamide) (IAB-NP), (2E,2′E)-2,2′-(3,3,6,6-tetramethyl-9-phenyl-3,4,6,7-tetrahydroacridine-1,8(2H,5H,9H,10H)-diylidene)bis(N-(2,4-difluorophenyl)hydrazinecarbothioamide)IAB-ND) and (2E,2′E)-2,2′-(3,3,6,6-tetramethyl-9-phenyl-3,4,6,7-tetrahydroacridine-1,8(2H,5H,9H,10H)-diylidene)bis(N-(2-fluorophenyl) hydrazinecarbothioamide) (IAB-NF) on mild steel corrosion in 1 M HCl solution. From the studies, compounds IAB-NP, IAB-ND and IAB-NF inhibit mild steel corrosion in the acid and the protection efficiencies were found to increase with the increase in concentration of each compound. At the optimum inhibitor concentration of 1.5 × 10−4 M, the inhibition efficiencies (%) of the compounds are in the order IAB-NF (90.48) > IAB-ND (87.48) > IAB-NP (85.28). Potentiodynamic polarization measurements revealed that all the compounds acted as mixed-type corrosion inhibitors. Experimental data for the adsorption of the studied molecules on a mild steel surface in 1 M HCl fitted into the Langmuir adsorption isotherm and the standard free energies of adsorption (ΔGoads) suggested both physisorption and chemisorption mechanisms. Scanning electron microscopy analyses confirmed the formation of a protective film on the mild steel surface by the inhibitor molecules, resulting in protection of the metal from corrosive electrolyte ions. The experimental findings were corroborated by both theoretical density functional theory and Monte Carlo simulation studies.Three novel acridine-based thiosemicarbazones were investigated for their corrosion inhibition potentials on mild steel in 1 M HCl using combined electrochemical, DFT and Monte Carlo simulation techniques. 相似文献
94.
95.
间硝地平对左室肥厚大鼠左室舒张功能及心脑线粒体和血管组织钙含量的影响 总被引:1,自引:0,他引:1
用肾性高血压左室肥厚(LVH)大鼠模型,观察了间硝地平(m-Nif)和硝苯地平(Nif)长期给药(ig20mg·kg-1·d-1持续9周)对左室舒张功能、左心室肌和大脑线粒体及血管钙含量的影响。与假手术组相比,LVH组左室顺应性明显下降,僵硬度增高,左心室肌和大脑线粒体及尾动脉和主动脉钙含量增加。与LVH组相比,m-Nif和Nif各组左室顺应性改善,僵硬度降低(P<0.01),左心室肌线粒体及尾动脉和主动脉钙含量较LVH组显著降低(P<0.01)。两药在作用强度上无显著差异。 相似文献
96.
The development of a method to facilitate clinical negotiationwith diabetic patients is described. The principles of the methodincorporate patient centredness, an assessment of readinessto change and some elements of motivational interviewing. Asimple low cost technology is part of the innovative method.Details of the method and its application are published beforethe results of a randomized controlled trial to ensure thatthe techniques are in the public domain before the outcome ofthe trial is known. 相似文献
97.
Manna R; Todaro L; Latteri M; Gambassi G; Massi G; Grillo MR; Romito A; Caputo S; Gasbarrini GB 《Rheumatology (Oxford, England)》1997,36(1):124-125
The actiopathogenesis of leucocytoclastic vasculitis is still unknown, but
recently hepatitis C virus (HCV) has been suggested as trigger of
autoimmunity. We report a case of a 26-yr-old patient with purpura due to
leucocytoclastic vasculitis associated with hepatitis C virus infection.
Laboratory findings showed AST, ALT, gamma GT within normal limits,
positive antibodies to HCV (IIF and Riba II) and polymerase chain reaction
for HCV RNA. Anti-nuclear antibodies, IgG and IgM anti- cardiolipin
antibodies, anti-platelet antibodies and anti-neutrophil cytoplasmic
antibodies with perinuclear pattern were also present. A skin biopsy
specimen of a purpuric lesion showed leucocytoclastic vasculitis with small
vessel thrombosis and perivascular deposition of IgM and fibrinogen on
immunofluorescence study. This case shows a role of HCV in leucocytoclastic
vasculitis; it is possible that this HCV can induce autoimmunity
independently of cryoglobulins and liver involvement.
相似文献
98.
Differentiation of thrombi from slow flow in the pulmonary arteries, sometimes observed in the presence of pulmonary arterial hypertension, can be equivocal. Magnetic resonance (MR) imaging was performed in a patient with chronic pulmonary thromboembolism and pulmonary arterial hypertension using an electrocardiographically gated technique that allowed visualization of the pulmonary arteries at the end of diastole and multiple times during systole. These images were compared with those of a patient with primary pulmonary hypertension and those of healthy subjects. Thrombi were discrete structures, seen throughout the cardiac cycle on both the first and second spin-echo images, and decreased in signal intensity on the second image. Slow flow increased in signal intensity and changed in structure during the cardiac cycle and was seen best on the second image. MR may play an important role in excluding large central thrombi as the cause of pulmonary arterial hypertension. It is a noninvasive method for defining pulmonary arterial wall thickness and for direct visualization of chronic pulmonary thrombus. 相似文献
99.
G Micali † MR Nasca † R De Pasquale † D Innocenzi‡ 《Journal of the European Academy of Dermatology and Venereology》2003,17(3):320-323
Kaposi's sarcoma is a vascular tumour of multifocal origin occurring primarily on the extremities. The case of a 45-year-old HIV negative and HHV-8 positive man with an asymptomatic reddish macular lesion on the inner layer of the prepuce is described. Although primary penile Kaposi's sarcoma is a relatively uncommon disorder in HIV negative men, dermatologists and venereologists should consider this possibility when treating non-specific penile lesions. A minimal penile lesion with non-distinctive clinical features may sometimes be the exclusive manifestation of Kaposi's sarcoma, making histologic evaluation necessary to establish the diagnosis. 相似文献
100.
MR Carvalho ; MA Krieger ; E Almeida ; W Oelemann ; MA Shikanai-Yassuda ; AW Ferreira ; JB Pereira ; A Saez-Alquezar ; PE Dorlhiac-Llacer ; DF Chamone ; et al. 《Transfusion》1993,33(10):830-834
Blood transfusion is one of the principal routes of transmission of Chagas' disease, a major endemic disease in Latin America. Methods for blood screening are not accurate and may yield false results that lead to high social and economic costs. This study compares two methods of diagnosing Chagas' disease (indirect immunofluorescence and hemagglutination) and several enzyme-linked immunosorbent assays (ELISAs) with regard to specificity and sensitivity, by using human sera with known serologic and parasitologic characteristics, as well as samples with discrepant results on conventional serologic tests. An ELISA using recombinant antigens showed no cross-reactivity with sera that were positive for other diseases. All evaluated ELISAs performed well, and their use may lead to a reduction of more than 50 percent in the number of discordant sera. Further improvements are needed in view of the complexity of the serologic diagnosis of Chagas' disease. 相似文献