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排序方式： 共有3954条查询结果，搜索用时 31 毫秒
51.
Susanna L. den Boer MD PhD Gideon J. du Marchie Sarvaas MD Liselotte M. Klitsie MD PhD Gabriëlle G. van Iperen MD Ronald B. Tanke MD PhD Willem A. Helbing MD PhD Ad P.C.M. Backx MD Lukas A.J. Rammeloo MD Michiel Dalinghaus MD PhD Arend D.J. ten Harkel MD PhD 《Echocardiography (Mount Kisco, N.Y.)》2017,34(6):881-887
52.
Periodontal treatment limits platelet activation in patients with periodontitis—a controlled‐randomized intervention trial 
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下载免费PDF全文 53.
Jenny Deluca Lukas Tappeiner Maria Pichler Klaus Eisendle 《Journal der Deutschen Dermatologischen Gesellschaft》2014,12(11):1060-1062
Reconstructions of large surgical defects of the central part of the nose pose a challenge for the surgeon due to its cosmetically prominent location. Treatment options include second intention healing, full‐thickness skin grafts and various local flaps. In the present case the “Peng flap” was used for the reconstruction of a 3.1 × 7 cm sized deep defect of the convex curve of the central nasal area in a 66‐year‐old woman. The Peng flap was performed as single‐stage procedure without complications. Good cosmetic outcome was provided by the use of adjacent skin from the lax perinasal area, the placement of the scar lines between facial cosmetic units, and the excellent tissue match for the sebaceous nasal skin. Considering the few complications of a single‐stage procedure associated with an excellent aesthetic outcome, the Peng flap should be considered not only as an effective choice for reconstruction of the cosmetically complex midline nasal tip but also the convex curve of the central nose. 相似文献
54.
Tactile stimulation during neonatal transition and its effect on vital parameters in neonates during neonatal transition 下载免费PDF全文
下载免费PDF全文 55.
Gleason grade 4 prostate adenocarcinoma patterns: an interobserver agreement study among genitourinary pathologists 下载免费PDF全文
下载免费PDF全文 Charlotte F Kweldam Daan Nieboer Ferran Algaba Mahul B Amin Dan M Berney Athanase Billis David G Bostwick Lukas Bubendorf Liang Cheng Eva Compérat Brett Delahunt Lars Egevad Andrew J Evans Donna E Hansel Peter A Humphrey Glen Kristiansen Theodorus H van der Kwast Cristina Magi‐Galluzzi Rodolfo Montironi George J Netto Hemamali Samaratunga John R Srigley Puay H Tan Murali Varma Ming Zhou Geert J L H van Leenders 《Histopathology》2016,69(3):441-449
56.
PD‐1 and PD‐L1 expression in HNSCC primary cancer and related lymph node metastasis – impact on clinical outcome 下载免费PDF全文
下载免费PDF全文 57.
Michele Caraglio Lukas Schrack Gerhard Jung & Thomas Franosch 《Communications In Computational Physics》2021,29(2):628-648
Within the mode-coupling theory (MCT) of the glass transition, we reconsider the numerical schemes to evaluate the MCT functional. Here we propose nonuniform discretizations of the wave number, in contrast to the standard equidistant grid,
in order to decrease the number of grid points without losing accuracy. We discuss in
detail how the integration scheme on the new grids has to be modified from standard
Riemann integration. We benchmark our approach by solving the MCT equations numerically for mono-disperse hard disks and hard spheres and by computing the critical
packing fraction and the nonergodicity parameters. Our results show that significant
improvements in performance can be obtained employing a nonuniform grid. 相似文献
58.
59.
Lukas Frase Peter Selhausen Lukas Krone Sulamith Tsodor Friederike Jahn Bernd Feige Jonathan G. Maier Florian Mainberger Hannah Piosczyk Marion Kuhn Stefan Klöppel Annette Sterr Chiara Baglioni Kai Spiegelhalder Dieter Riemann Michael A. Nitsche Christoph Nissen 《Brain stimulation》2019,12(3):674-683
Background
Arousal and sleep represent basic domains of behavior, and alterations are of high clinical importance.Objective/hypothesis
The aim of this study was to further elucidate the neurobiology of insomnia disorder (ID) and the potential for new treatment developments, based on the modulation of cortical activity through the non-invasive brain stimulation technique transcranial direct current stimulation (tDCS). Specifically, we tested the hypotheses that bi-frontal anodal tDCS shortens and cathodal tDCS prolongs total sleep time in patients with ID, compared to sham stimulation. Furthermore, we tested for differences in indices of arousal between ID patients and healthy controls and explored their potential impact on tDCS effects.Methods
Nineteen ID patients underwent a within-subject repeated-measures sleep laboratory study with adaptation, baseline and three experimental nights. Bifrontal anodal, cathodal and sham tDCS was delivered in a counterbalanced order immediately prior to sleep. Wake EEG was recorded prior to and after tDCS as well as on the following morning. Subsequently, we compared patients with ID to a healthy control group from an earlier dataset.Results
Against our hypothesis, we did not observe any tDCS effects on sleep continuity or sleep architecture in patients with ID. Further analyses of nights without stimulation demonstrated significantly increased levels of arousal in ID patients compared to healthy controls, as indexed by subjective reports, reduced total sleep time, increased wake after sleep onset and increased high frequency EEG power during wakefulness and NREM sleep. Of note, indices of increased arousal predicted the lack of effect of tDCS in ID patients.Conclusions
Our study characterizes for the first time differential effects of tDCS on sleep in patients with ID and healthy controls, presumably related to persistent hyperarousal in ID. These findings suggest that adapted tDCS protocols need to be developed to modulate arousal and sleep dependent on baseline arousal levels. 相似文献60.