全文获取类型
收费全文 | 49660篇 |
免费 | 3713篇 |
国内免费 | 117篇 |
专业分类
耳鼻咽喉 | 394篇 |
儿科学 | 2112篇 |
妇产科学 | 1516篇 |
基础医学 | 6502篇 |
口腔科学 | 490篇 |
临床医学 | 6712篇 |
内科学 | 9323篇 |
皮肤病学 | 771篇 |
神经病学 | 4881篇 |
特种医学 | 1039篇 |
外国民族医学 | 38篇 |
外科学 | 4752篇 |
综合类 | 523篇 |
一般理论 | 100篇 |
预防医学 | 7200篇 |
眼科学 | 705篇 |
药学 | 2651篇 |
中国医学 | 85篇 |
肿瘤学 | 3696篇 |
出版年
2024年 | 76篇 |
2023年 | 492篇 |
2022年 | 722篇 |
2021年 | 1541篇 |
2020年 | 925篇 |
2019年 | 1453篇 |
2018年 | 1699篇 |
2017年 | 1233篇 |
2016年 | 1308篇 |
2015年 | 1377篇 |
2014年 | 1923篇 |
2013年 | 2814篇 |
2012年 | 3978篇 |
2011年 | 4082篇 |
2010年 | 2167篇 |
2009年 | 1891篇 |
2008年 | 3411篇 |
2007年 | 3368篇 |
2006年 | 3104篇 |
2005年 | 3041篇 |
2004年 | 2743篇 |
2003年 | 2452篇 |
2002年 | 2302篇 |
2001年 | 313篇 |
2000年 | 211篇 |
1999年 | 321篇 |
1998年 | 467篇 |
1997年 | 361篇 |
1996年 | 303篇 |
1995年 | 307篇 |
1994年 | 262篇 |
1993年 | 232篇 |
1992年 | 155篇 |
1991年 | 159篇 |
1990年 | 140篇 |
1989年 | 115篇 |
1988年 | 118篇 |
1987年 | 88篇 |
1986年 | 115篇 |
1985年 | 111篇 |
1984年 | 126篇 |
1983年 | 106篇 |
1982年 | 124篇 |
1981年 | 165篇 |
1980年 | 110篇 |
1979年 | 69篇 |
1978年 | 59篇 |
1977年 | 62篇 |
1976年 | 63篇 |
1974年 | 65篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
21.
Tolerance of ocular iontophoresis in healthy volunteers. 总被引:4,自引:0,他引:4
Thomas M Parkinson Elizabeth Ferguson Salvatore Febbraro Arash Bakhtyari Martin King Mohan Mundasad 《Journal of ocular pharmacology and therapeutics》2003,19(2):145-151
To evaluate ocular tolerance, healthy volunteers were iontophoresed transclerally using novel OcuPhor trade mark hydrogel drug delivery applicators filled with balanced salt solution. In this three-period crossover study in 24 male and female subjects, 16 subjects received 0 mA and two of the following DC currents: 0.1, 0.5., 1.0, 2.0, 3.0, or 4.0 mA for 20 min; 6 subjects received 3 mA for 20 min and 1.5 mA for 40 min (both equivalent to 60 mAmin total charge). Safety and tolerance were determined by subjective VAS and objective ophthalmic assessments. Subjects were evaluated before and up to 22 hr after dosing. The applicators were well-tolerated and no clinically significant changes in symptomology or in ophthalmic assessments were seen following exposure to 0-3.0 mA for 20 min or 1.5 mA for 40 min. At 4.0 mA 2 of 4 subjects reported a burning sensation under the applicator during dosing which resolved by 22 hr post-dose; superficial changes in fluorescein staining were observed at 1 hr, but not at 22 hr. The OcuPhor trade mark system has promise for noninvasive drug delivery to the eye. 相似文献
22.
We report a full-term male infant born to nonconsanguinous parents who had clinical features of Goldenhar syndrome and cri du chat syndrome. At birth, the infant was noted to have dysmorphic features with bilateral preauricular tags, rotated ears, bilateral epicanthic folds, a left epibulbar lipodermoid, and an accessory left nipple. After he was assessed for feeding difficulty and tachypnea, he was found to have esophageal atresia with tracheoesophageal fistula. In addition, he had a high-pitched, cat-like cry, characteristic of cri-du-chat syndrome. He also failed a hearing test. Chromosomal analysis and fluorescence in situ hybridisation studies showed an unbalanced karyotype with a terminal deletion of the segment p14 on the short arm of chromosome 5, which is consistent with the cri-du-chat locus. The association of Goldenhar syndrome and cri-du-chat syndrome in this patient suggests that the chromosome 5p14 locus may harbor a gene implicated with Goldenhar syndrome. 相似文献
23.
Sandra Urdaneta Hartmann Brian Wigdahl Elizabeth B Neely Cheston M Berlin Cara-Lynne Schengrund Hung-Mo Lin Mary K Howett 《Journal of human lactation》2006,22(1):61-74
Reduction of transmission of human immunodeficiency virus type 1 (HIV-1) through human milk is needed. Alkyl sulfates such as sodium dodecyl sulfate (SDS) are microbicidal against HIV-1 at low concentrations, have little to no toxicity, and are inexpensive. The authors have reported that treatment of HIV-1-infected human milk with < or = 1% (10 mg/mL) SDS for 10 minutes inactivates cell-free and cell-associated virus. The SDS can be removed with a commercially available resin after treatment without recovery of viral infectivity. In this article, the authors report results of selective biochemical analyses (ie, protein, immunoglobulins, lipids, cells, and electrolytes) of human milk subjected to SDS treatment and removal. The SDS treatment or removal had no significant effects on the milk components studied. Therefore, the use of alkyl sulfate microbicides to treat milk from HIV-1-positive women may be a simple, practical, and nutritionally sound way to prevent or reduce transmission of HIV-1 while still feeding with mother's own milk. 相似文献
24.
25.
Elizabeth Bass Robert R Campbell Dennis C Werner Audrey Nelson Tatjana Bulat 《Rehabilitation nursing》2004,29(6):215-220
Hip fractures among elderly people frequently result in permanent disabilities, nursing home placement, and death. The bulk of hip fracture research focuses on elderly women. Within the Veterans Health Administration (VHA), the majority of patients are men. There are no published national reports on hip fractures with large male samples, or on related inpatient mortality among veterans. This retrospective study of 13,546 veterans with hip fracture discharges from 1998-2002 found unadjusted mortality rates are higher in the VHA, compared with the general population. VHA patients tend to be older men in poor health who stay in the hospital longer Increased knowledge about the risks and outcomes associated with hip fractures in men could lead to improved primary and secondary injury-prevention programs. Rehabilitation nurses in acute care can be catalysts in proactively incorporating protective devices, screening for osteoporosis, and initiating lifestyle changes in their plans of care to optimize outcomes for hip fracture patients. 相似文献
26.
Elizabeth E. Epstein Barbara S. McCrady Linda S. Hirsch 《Alcoholism, clinical and experimental research》1997,21(3):547-556
Current knowledge about alcohol and marital functioning is limited by restrictive sample selection, inattention to the literature on individual-based alcoholic subtypes, and lack of research linking individual differences among alcoholics to marital functioning. The present study was designed to study marital functioning of alcoholics in light of current alcohol typologies. Subjects were part of a larger study on conjoint treatment of alcoholic males and their female partners. Four typologies—including Type 1/2, In-Home/Out-of-home, SteadyIEpisodic, and EarlyILate Onset—were tested for replicability and discriminant validity before linking them to marital functioning. Discriminant validity was found only for the Early (59%)-versus Late (41 %)-Onset typology; thus, further analyses linked only this typology with marital functioning. At baseline, Early-Onset couples reported more marital instability, and the females in these couples were more distressed. During treatment, Early-Onset couples reported higher daily marital satisfaction than Late-Onset couples. Regardless of age of onset, males reported higher marital satisfaction than their spouses during treatment, but their satisfaction did not increase during treatment. Female partners' marital satisfaction increased during treatment. Female partners of Late-Onset males reported particularly low marital satisfaction during treatment. Parsing the sample according to the early-/late-onset typology yielded different predictors of marital satisfaction for males and females within each subtype. For female partners of Early-Onset alcoholics, psychological distress unrelated to her pattner's drinking severity was most associated with her own marital satisfaction, whereas marital adjustment of female partners of Late-Onset alcoholics was most associated with the male's level of perceptual accuracy regarding her needs. This pattern was reversed for the males; marital adjustment of Early-Onset alcoholics was most associated with his partner's perceptual accuracy of his needs, whereas marital functioning of Late-Onset alcoholics was best accounted for by his own psychological distress. 相似文献
27.
28.
J Emerg Nurs 1998;24:622. 相似文献
29.
30.
David A Todd MSc PhD John Kennedy FRACO † Sharyn Roberts RN Jane Watts RN Kim Psaila RN BApplSc Elizabeth John MD FRACP 《Clinical & experimental ophthalmology》1994,22(1):19-23
From January 1986 to December 1991 we examined the eyes of 206 infants born at Westmead Hospital, Neonatal Intensive Care Unit who were less than 29 weeks' gestation at birth to determine the incidence of retinopathy of prematurity. Eighty-five infants (41.3%) had no retinopathy of prematurity (ROP) in either eye, 82 infants had stages 1 or 2 ROP (39.8%), 29 had stage 3 ROP (14.1%) and 11 had stage 4 ROP (5.3%). Of these, cryotherapy was performed in 18; six now have bilateral retinal detachment and are blind The more severe stages of ROP were significantly associated with an increase in the number of days of oxygen supplementation, an increase in the number of days of mechanical ventilation and the presence of patent ductus arteriosus. Infants receiving steroids for mechanical ventilator dependence had a significantly greater chance of requiring cryotherapy (11 or 22 receiving steroids versus seven of 43 without steroids; P < 0.01). 相似文献