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101.
心脏病患者血清七种元素含量与血压及生化指标的关系 总被引:31,自引:0,他引:31
我们检测了心脏病患者血清微量元素Zn、Cu、Fe和常量元素K、Na、Ca、Mg的含量,并与血压及生化指标作相关分析。结果发现心脏病患者K和Ca/Mg显著低于对照组,而Na、Mg、Zn、Fe和Na/K、Zn/Cu则显著高于对照组。K、Ca/Mg与血压呈负相关,而Na、Zn、Fe、Zn/Cu和Na/K与血压呈正相关;Fe与红细胞压积(Hct)呈正相关;Zn/Cu与Hct、甘油三酯、极低密度脂蛋白均呈正相关,而与高密度脂蛋白呈负相关。 相似文献
102.
Transitional mucosa adjacent to colorectal cancers is essentially characterized by an excess of sialomucins at the expense of the normally predominant sulphomucins in epithelial cells lining the intestinal crypts which presents the early stage of oncogenic transformation of colorectal epithelium. The presence or absence of sialomucins at the resection margins was studied histochemically using the high iron diamine-alcian blue(HID-AB) stain in 64 rectal cancer patients in Dukes' B stage who underwent curative anterior resection. The correlation was revealed between the presence of sialomucins at the resection margins and subsequent development of local tumour recurrence. Fourteen of 27 patients (51.9%) with sialomucins predominant pattern at either resection margin developed local recurrence compared with 4 of 37 patients (10.8%) with sulphomucins predominant pattern (P less than 0.001). It is suggested that determination of the transitional mucosa around anastomosis in patients treated for the rectal carcinoma by anterior resection appears to identify those with a higher risk of local recurrence. 相似文献
103.
Xiaohua He Edith V Sullivan Roger K Stankovic Clive G Harper Adolf Pfefferbaum 《Neuropsychopharmacology》2007,32(10):2207-2216
The relative roles of alcohol and thiamine deficiency in causing brain damage remain controversial in alcoholics without the Wernicke-Korsakoff syndrome. Experimental control over alcohol consumption and diet are impossible in humans but can be accomplished in animal models. This experiment was designed to differentiate the separate and combined effects on the macro- and ultrastructure of the corpus callosum of thiamine deficiency and voluntary alcohol consumption. Adult male alcohol-preferring (P) rats (9 chronically alcohol-exposed and 9 water controls) received a thiamine-deficient diet for 2 weeks. There were four groups: five rats previously exposed to alcohol were treated with pyrithiamine (a thiamine phosphorylation inhibitor); five rats never exposed to alcohol were treated with pyrithiamine; four alcohol-exposed rats were treated with thiamine; and four rats never exposed to alcohol were treated with thiamine. On day 14, thiamine was restored in all 18 rats; 2 weeks later the 10 pyrithiamine-treated rats received intraperitoneal thiamine. The rats were perfused 61 days post-pyrithiamine treatment at age 598 days. Brains were dissected and weight and volumes were calculated. Sagittal sections were stained to measure white matter structures. The corpus callosum was examined using transmission electron microscopy to determine density of myelinated fibers, fiber diameter, and myelin thickness. The corpus callosum in the alcohol/pyrithiamine group was significantly thinner, had greater fiber density, higher percentage of small fibers, and myelin thinning than in the alcohol/thiamine and water/thiamine groups. Several measures showed a graded effect, where the alcohol/pyrithiamine group had greater pathology than the water/pyrithiamine group, which had greater pathology than the two thiamine-replete groups. Across all 16 rats, thinner myelin sheaths correlated with higher percentage of small fibers. Myelin thickness and axon diameter together accounted for 71% of the variance associated with percentage of small fibers. Significant abnormalities in the alcohol/pyrithiamine group and lack of abnormality in the alcohol-exposed/thiamine-replete group indicate that thiamine deficiency caused white matter damage. The graded abnormalities across the dually to singly treated animals support a compounding effect of alcohol exposure and thiamine depletion, and indicate the potential for interaction between alcohol and thiamine deficiency in human alcohol-related brain damage. 相似文献
104.
目的研究妊高征孕妇心率变异性(HRV)、血压变异性(BPV)和压力反射敏感性(BRS)的改变.方法用无创伤测定和频谱分析方法,检测31名正常妊娠孕妇和19名中、重度妊高征孕妇的HRV、BPV和自发性BRS,数据用SPSS 10.0软件分析.结果妊高征组和正常妊娠组相比,HRV各指标有下降趋势,但无统计学意义(P>0.05).妊高征孕妇BPV的低频成分显著高于正常妊娠孕妇(P<0.05),BRS较正常妊娠孕妇降低(P<0.05).结论妊高征孕妇交感神经对血压调节的活动性较正常妊娠孕妇增强;压力反射功能受损可能是妊高征发病过程中一重要环节. 相似文献
105.
106.
目的:探讨奎的平、氯氮平对精神分裂症的疗效及副作用。方法:80例患者随机分为两组,分别应用奎的平或氯氮平治疗6周,采用四级临床疗效评定标准、阳性症状与阴性症状量表(PANSS)、副反应量表(TESS)评定疗效及副反应。结果:奎的平组有效率87.5%,氯氮平组有效率82.5%。治疗第一周末,奎的平组PANSS量表总分较治疗前差异有显著性(P<0.05)。奎的平组副反应低于氯氮平组。结论:奎的平与氯氮平疗效相似,但奎的平起效较快,副反应较轻。 相似文献
107.
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109.
采用聚丙烯酰胺凝胶垂直平板电泳技术,对湖北和四川两省5种拟钉螺的酯酶同工酶酶谱进行比较研究,并以湖北钉螺作对照,5种拟钉螺酯酶同工酶共分离出8条酶带,酶谱可分成3区,即EST-1、EST-2、EST-3,其基本特征与钉螺显著不同,很容易通过酶谱将拟钉螺与钉螺区分开,同时,5种拟钉螺的酯酶同工酶酶谱之间均存在一定的差异,说明拟钉螺种间酯酶同工酶存在多态,而种间差异程度似与地域隔离的远近有关。结果提示拟钉螺酯酶同工酶的酶谱特征既有助于拟钉螺属的鉴定,又有助于拟钉螺近缘种的区分,从而对拟钉螺的分类有较大的参考价值。 相似文献
110.