全文获取类型
收费全文 | 2623篇 |
免费 | 269篇 |
国内免费 | 4篇 |
专业分类
耳鼻咽喉 | 13篇 |
儿科学 | 112篇 |
妇产科学 | 47篇 |
基础医学 | 269篇 |
口腔科学 | 32篇 |
临床医学 | 444篇 |
内科学 | 467篇 |
皮肤病学 | 17篇 |
神经病学 | 342篇 |
特种医学 | 95篇 |
外科学 | 316篇 |
综合类 | 48篇 |
预防医学 | 323篇 |
眼科学 | 60篇 |
药学 | 172篇 |
中国医学 | 3篇 |
肿瘤学 | 136篇 |
出版年
2023年 | 32篇 |
2022年 | 32篇 |
2021年 | 88篇 |
2020年 | 54篇 |
2019年 | 97篇 |
2018年 | 85篇 |
2017年 | 64篇 |
2016年 | 86篇 |
2015年 | 65篇 |
2014年 | 113篇 |
2013年 | 150篇 |
2012年 | 174篇 |
2011年 | 221篇 |
2010年 | 107篇 |
2009年 | 97篇 |
2008年 | 159篇 |
2007年 | 149篇 |
2006年 | 147篇 |
2005年 | 133篇 |
2004年 | 113篇 |
2003年 | 96篇 |
2002年 | 94篇 |
2001年 | 34篇 |
2000年 | 22篇 |
1999年 | 17篇 |
1998年 | 19篇 |
1997年 | 15篇 |
1996年 | 13篇 |
1995年 | 14篇 |
1994年 | 20篇 |
1993年 | 19篇 |
1992年 | 29篇 |
1991年 | 25篇 |
1990年 | 21篇 |
1989年 | 16篇 |
1988年 | 22篇 |
1987年 | 13篇 |
1986年 | 21篇 |
1985年 | 25篇 |
1984年 | 23篇 |
1983年 | 23篇 |
1981年 | 10篇 |
1979年 | 15篇 |
1978年 | 9篇 |
1974年 | 9篇 |
1972年 | 10篇 |
1971年 | 8篇 |
1970年 | 8篇 |
1969年 | 8篇 |
1967年 | 7篇 |
排序方式: 共有2896条查询结果,搜索用时 15 毫秒
31.
Antibiotics and surgery for vesicoureteric reflux: a meta-analysis of randomised controlled trials. 总被引:3,自引:0,他引:3
D Wheeler D Vimalachandra E M Hodson L P Roy G Smith J C Craig 《Archives of disease in childhood》2003,88(8):688-694
AIMS: To evaluate the benefits and harms of treatments for vesicoureteric reflux in children. METHODS: Meta-analyses of randomised controlled trials using a random effects model. Main outcome measures were incidence of urinary tract infection (UTI), new or progressive renal damage, renal growth, hypertension, and glomerular filtration rate. RESULTS: Eight trials involving 859 evaluable children comparing long term antibiotics with surgical correction of reflux (VUR) and antibiotics (seven trials) and antibiotics compared with no treatment (one trial) were identified. Risk of UTI by 1-2 and 5 years was not significantly different between surgical and medical groups (relative risk (RR) by 2 years 1.07; 95% confidence interval (CI) 0.55 to 2.09, RR by 5 years 0.99; 95% CI 0.79 to 1.26). Combined treatment resulted in a 60% reduction in febrile UTI by 5 years (RR 0.43; 95% CI 0.27 to 0.70) but no concomitant significant reduction in risk of new or progressive renal damage at 5 years (RR 1.05; 95% CI 0.85 to 1.29). In one small study no significant differences in risk for UTI or renal damage were found between antibiotic prophylaxis and no treatment. CONCLUSION: It is uncertain whether the identification and treatment of children with VUR confers clinically important benefit. The additional benefit of surgery over antibiotics alone is small at best. Assuming a UTI rate of 20% for children with VUR on antibiotics for five years, nine reimplantations would be required to prevent one febrile UTI, with no reduction in the number of children developing any UTI or renal damage. 相似文献
32.
Increase in exhaled carbon monoxide during exacerbations of cystic fibrosis 总被引:5,自引:1,他引:4
下载免费PDF全文
![点击此处可从《Thorax》网站下载免费的PDF全文](/ch/ext_images/free.gif)
BACKGROUND: Non-invasive assessment of inflammation is likely to be useful in the management of cystic fibrosis (CF). Exhaled carbon monoxide (CO) concentrations are increased in patients with clinically stable CF. A study was undertaken to determine whether this marker of oxidative damage is further increased during exacerbations of the disease. METHODS: Exhaled CO concentrations were measured in 12 healthy non-smoking control subjects (six men) of mean (SE) age 37 (2) years with forced expiratory volume in one second (FEV(1)) 95 (1)% predicted and in 44 patients with CF (20 men) of mean (SE) age 29 (1) years with FEV(1) 56 (3)% predicted using an on-line CO analyser. RESULTS: Twenty nine patients were in a stable condition while 15 had clinically defined respiratory exacerbations (increased cough and production of sputum, change in the quality of the sputum, shortness of breath, sensation of chest congestion, and deterioration of FEV(1)) and represented the unstable group. Exhaled CO concentrations were 2.0 (0.15) ppm in the control group, were increased in the stable CF group to 2.7 (0.13) ppm (differences between means -0.67 (0.22), 95% confidence interval (CI) 0.22 to 1.12, p<0.01) and further increased in the unstable group to 4.8 (0.3) ppm (differences between means -2.15 (0.32), 95% CI 1.50 to 2.79, p<0.001). A significant correlation was found between the deterioration in FEV(1) and exhaled CO concentrations. CONCLUSIONS: This study shows that the measurement of exhaled CO is of potential value as an indicator of exacerbations in patients with CF and could be used as a simple method to monitor the course of the disease. 相似文献
33.
The case history is presented of a lung transplant patient who developed prolonged parvovirus B19 infection with severe transfusion dependent anaemia. The patient was treated with intravenous immunoglobulin after which the haemoglobin rose, together with a reticulocytosis. The patient then remained transfusion free and the virus cleared more than three months after the initial immunoglobulin treatment. The clinical and social implications for this group of patients are discussed. 相似文献
34.
35.
36.
37.
38.
39.
40.