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81.
Alexander Ayala Kyle Tegtmeyer Giancarlo Atassi Elizabeth Powell 《The Journal of emergency medicine》2021,60(5):661-668
BackgroundProlonged emergency department (ED) wait times could potentially lead to increased morbidity and mortality. While previous work has demonstrated disparities in wait times associated with race, information about the relationship between experiencing homelessness and ED wait times is lacking.ObjectivesThe purpose of this study was to explore the relationship between residence status (undomiciled vs. domiciled) and ED wait times. We hypothesized that being undomiciled would be associated with longer wait times.MethodsWe obtained data from the National Hospital Ambulatory Medical Care Survey from 2014 to 2017. We compared wait times in each triage category using t tests. We used multivariate linear regression to explore associations between residence status and wait times while controlling for other patient- and hospital-level variables.ResultsOn average, undomiciled patients experienced significantly longer mean ED wait times than domiciled patients (53.4 vs. 38.9 min; p < 0.0001). In the multivariate model, undomiciled patients experienced significantly different wait times by 15.5 min (p = 0.0002). Undomiciled patients experienced increasingly longer waits vs. domiciled patients for the emergent and urgent triage categories (+33.5 min, p < 0.0001, and +22.7 min, p < 0.0001, respectively).ConclusionsUndomiciled patients experience longer ED wait times when compared with domiciled patients. This disparity is not explained by undomiciled patients seeking care in the ED for minor illness, because the disparity is more pronounced for urgent and emergent triage categories. 相似文献
82.
Ticiana A. Leal Angela C. Argento Krish Bhadra D. Kyle Hogarth Julia Grigorieva Rachel M. Hartfield 《Current medical research and opinion》2020,36(9):1497-1505
Abstract
Objective
Timely assessment of patient-specific prognosis is critical to oncology care involving a shared decision-making approach, but clinical prognostic factors traditionally used in NSCLC have limitations. We examine a proteomic test to address these limitations. 相似文献83.
Nicole Bohm Charles Makowski Mario Machado Adam Davie Nelson Seabrook Lee Wheless Benjamin Bevill Bradley Clark T. Rogers Kyle III 《Antimicrobial agents and chemotherapy》2014,58(8):4902-4903
A patient receiving daptomycin developed asymptomatic transaminitis and hyperbilirubinemia without concurrent multiorgan dysfunction or elevation of his creatinine kinase level. After ruling out other etiologies, the liver injury was attributed to daptomycin and was subsequently resolved. A single-center retrospective cohort analysis of baseline and follow-up liver function panels (n = 614) from all admissions from 2008 to 2013 during which daptomycin was administered did not reveal any other cases of probable or definite drug-induced liver injury associated with daptomycin. 相似文献
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85.
Maciej Kmieciak Kyle K Payne Michael O Idowu Margaret M Grimes Laura Graham Maria-Libera Ascierto Ena Wang Xiang-Yang Wang Harry D Bear Masoud H Manjili 《Journal of translational medicine》2011,9(1):35
Background
Emerging data from pre-clinical and clinical studies suggest that HER-2/neu-specific T cell responses could induce HER-2/neu antigen loss in the tumor cells. These data suggest that patients with HER-2/neu negative breast cancer might have had HER-2/neu positive premalignant lesions in the past that progressed to HER-2/neu negative breast cancer under HER-2/neu-specific immune pressure. 相似文献86.
Chinthaka C. Heyn Jonathan Bishop Kyle Duffin Wayne Lee Jun Dazai Shoshana Spring Brian J. Nieman John G. Sled 《NMR in biomedicine》2017,30(11)
Blood temperature is a key determinant of tissue temperature and can be altered under normal physiological states, such as exercise, in diseases such as stroke or iatrogenically in therapies which modulate tissue temperature, such as therapeutic hypothermia. Currently available methods for the measurement of arterial and venous temperatures are invasive and, for small animal models, are impractical. Here, we present a methodology for the measurement of intravascular and tissue temperature by magnetic resonance imaging (MRI) using the lanthanide agent TmDOTMA? (DOTMA, tetramethyl‐1,4,7,10‐tetraazacyclododecane‐1,4,7,10‐tetraacetic acid; Tm, thulium). The approach makes use of phase‐sensitive imaging measurements, combined with spectrally selective excitation, to monitor the temperature‐dependent shift in the resonance of proton nuclei associated with water and with methyl groups of TmDOTMA?. Measurements were first made in a flow phantom modelling diastolic blood flow in the mouse aorta or inferior vena cava (IVC) and imaged using 7‐T preclinical MRI with a custom‐built surface coil. Flowing and static fluid temperatures agreed to within 0.12°C for these experiments. Proof‐of‐concept experiments were also performed on three healthy adult mice, demonstrating temperature measurements in the aorta, IVC and kidney following a bolus injection of contrast agent. A small (0.7–1°C), but statistically significant, higher kidney temperature compared with the aorta (p = 0.002–0.007) and IVC (p = 0.003–0.03) was shown in all animals. These findings demonstrate the feasibility of the technique for in vivo applications and illustrate how the technique could be used to explore the relationship between blood and tissue temperature for a wide range of applications. 相似文献
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88.
Kyle W. Pfahl M.D. David A. Orsinelli M.D. Subha Raman M.D. Michael Firstenberg M.D. 《Echocardiography (Mount Kisco, N.Y.)》2013,30(10):E304-E306
Aneurysms of the coronary arteries are rare and are usually associated with atherosclerosis in adults. Mycotic coronary artery aneurysms are exceedingly uncommon and are typically associated with systemic bacteremia, endocarditis, or septic emboli. Literature and data describing the management of mycotic coronary artery aneurysms are limited. This case describes the successful diagnosis of a large right coronary artery aneurysm by transesophageal echocardiogram as well as the successful management of the aneurysm. 相似文献
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90.