全文获取类型
收费全文 | 5647篇 |
免费 | 434篇 |
国内免费 | 54篇 |
专业分类
耳鼻咽喉 | 23篇 |
儿科学 | 91篇 |
妇产科学 | 189篇 |
基础医学 | 677篇 |
口腔科学 | 85篇 |
临床医学 | 545篇 |
内科学 | 1243篇 |
皮肤病学 | 88篇 |
神经病学 | 559篇 |
特种医学 | 231篇 |
外科学 | 934篇 |
综合类 | 89篇 |
一般理论 | 1篇 |
预防医学 | 280篇 |
眼科学 | 80篇 |
药学 | 431篇 |
中国医学 | 60篇 |
肿瘤学 | 529篇 |
出版年
2023年 | 51篇 |
2022年 | 113篇 |
2021年 | 184篇 |
2020年 | 110篇 |
2019年 | 176篇 |
2018年 | 157篇 |
2017年 | 126篇 |
2016年 | 177篇 |
2015年 | 222篇 |
2014年 | 273篇 |
2013年 | 317篇 |
2012年 | 462篇 |
2011年 | 463篇 |
2010年 | 303篇 |
2009年 | 267篇 |
2008年 | 342篇 |
2007年 | 348篇 |
2006年 | 260篇 |
2005年 | 285篇 |
2004年 | 230篇 |
2003年 | 193篇 |
2002年 | 156篇 |
2001年 | 88篇 |
2000年 | 78篇 |
1999年 | 72篇 |
1998年 | 38篇 |
1997年 | 25篇 |
1996年 | 30篇 |
1995年 | 28篇 |
1994年 | 13篇 |
1993年 | 20篇 |
1992年 | 45篇 |
1991年 | 50篇 |
1990年 | 45篇 |
1989年 | 37篇 |
1988年 | 37篇 |
1987年 | 43篇 |
1986年 | 33篇 |
1985年 | 27篇 |
1984年 | 24篇 |
1983年 | 18篇 |
1982年 | 16篇 |
1981年 | 12篇 |
1980年 | 14篇 |
1979年 | 17篇 |
1978年 | 20篇 |
1977年 | 12篇 |
1974年 | 16篇 |
1973年 | 9篇 |
1972年 | 12篇 |
排序方式: 共有6135条查询结果,搜索用时 143 毫秒
91.
92.
93.
94.
95.
96.
97.
Therapeutic leukocytapheresis for improvement in respiratory function in a woman with hyperleukocytosis and mantle cell lymphoma with a circulating small lymphocyte phenotype 下载免费PDF全文
Laura Kwan Jeanne Linden Kathleen Gaffney Mindy Greene Michelle Vauthrin Muthalagu Ramanathan Robert Weinstein 《Journal of clinical apheresis》2016,31(4):398-402
Mantle cell lymphoma is an aggressive malignant B‐cell disorder that often presents with a leukemic picture. Circulating lymphoma cell morphology may vary from small round mature‐appearing lymphocytes resembling the lymphocytes of chronic lymphocytic leukemia to large prolymphocytoid or blastoid cells. Rare reports of hyperleukocytosis with leukostasis, treated with leukocytapheresis, are described in patients with prolymphocytoid or blastoid morphology. We report an 88 year old woman with mantle cell lymphoma, hyperleukocytosis (WBC > 400 × 103/µL) with severe respiratory compromise but without interstitial or alveolar infiltrates on radiograph or computerized tomography of the chest. She was afebrile and had no central nervous system signs. Circulating lymphoma cell morphology was predominantly of the small lymphocyte type. A two‐whole‐blood‐volume leukocytapheresis reduced her WBC from 465 to 221 × 103/µL in 150 min. Her respiratory rate decreased from 28/min to 18/min and her arterial oxygen saturation (SpO2) rose from 91% to 97% on 6 L/min of oxygen by nasal cannula. Severe breathlessness before the procedure abated completely by the end of the procedure. Respiratory compromise may occur in mantle cell lymphoma with hyperleukocytosis with a mature lymphoma cell phenotype, even without a clear picture of leukostasis. Although the ultimate survival of the patient depends on treatment with chemotherapy, leukocytapheresis for alleviation of symptoms may be warranted and should be considered. Respiratory status and response to leukocytapheresis should be documented with physiological measurements. J. Clin. Apheresis 31:398–402, 2016. © 2015 Wiley Periodicals, Inc. 相似文献
98.
The impact of a Web‐based educational program on the recognition and management of deteriorating patients 下载免费PDF全文
99.
Antaki F Tringali A Deprez P Kwan V Costamagna G Le Moine O Delhaye M Cremer M Devière J 《Gastrointestinal endoscopy》2008,67(1):163-168
BACKGROUND: Duodenal duplication cysts are rare congenital anomalies. Symptomatic cases have classically been treated by surgical resection, which can be complex because of the close proximity of the cysts to the papilla. OBJECTIVE: To describe a series of 8 patients with symptomatic duodenal duplication cysts who were treated endoscopically, with a special focus on the long-term outcome. DESIGN: Retrospective case series. SETTING: Three tertiary-care European academic hospitals. PATIENTS: Eight patients, age 8 to 72 years, were treated endoscopically for symptomatic intraluminal duodenal duplication cysts between 1981 and 2006. Seven patients presented with acute pancreatitis, and one patient presented with jaundice. INTERVENTION: Endoscopic incision and marsupialization of the cysts was performed by using a variety of endoscopic tools (needle-knife and regular sphincterotomes, cystotomes, and polypectomy snares). MAIN OUTCOME MEASUREMENTS: Technical success of endoscopic intervention and long-term clinical recurrence of symptoms. RESULTS: No major complications occurred. All patients remained asymptomatic at a median follow-up of 7.3 years. LIMITATIONS: Retrospective study; the small number of patients. CONCLUSIONS: The endoscopic treatment of symptomatic intraluminal duodenal duplication cysts is a safe and effective technique, with excellent long-term results. It represents a minimally invasive alternative to surgical resection and might be considered the preferred therapeutic modality for these cases. 相似文献
100.