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ObjectiveRenal transplantation is the best treatment for end-stage renal disease. However, limited availability of donor organs is a problem. We analyzed the changing trends of transplantation and mortality in subjects listed for deceased donor renal transplantation over successive years.MethodsBy using US Renal Data System data, we identified Medicare patients receiving dialysis who were listed for their first deceased donor renal transplant between January 1996 and December 2005. Subjects were followed to the first occurrence of transplant, death, or September 30, 2007. The effect of the year of listing was analyzed adjusting for age, sex, race, vintage, panel reactive antibody, and cause of end-stage renal disease.ResultsThere were 70,891 subjects (mean age 50.1 ± 14.3 years, 59.9% were men, 54% were white, average duration of dialysis 2 ± 2.2 years). Multivariate analysis revealed that compared with patients listed in 1996, for patients listed in subsequent years the cumulative incidence of death remained within a narrow boundary and the cumulative incidence of transplant progressively declined. For example, for subjects listed in 1998, 2000, 2002, and 2004, the cumulative incidence of death relative to 1996 was 1.02 (95% confidence interval [CI], 1.01-1.03), 1.02 (CI, 1.01-1.03), 0.99 (CI, 0.98-0.99), and 0.94 (CI, 0.93-0.94), respectively, 12 months after listing. However, correspondingly for these subjects at the 12-month follow-up time point, the cumulative incidence of transplant relative to 1996 was 0.85 (CI, 0.84-0.86), 0.73 (CI, 0.71-0.74), 0.63 (CI, 0.62-0.64), and 0.58 (CI, 0.57-0.59), respectively.ConclusionThere is a progressive unfavorable pattern of declining transplantation rates with each successive year of listing in patients listed for deceased donor renal transplantation. 相似文献
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Akash Makkar Joann Prisciandaro Sunil Agarwal Morgan Lusk Laura Horwood Jean Moran Colleen Fox James A. Hayman Hamid Ghanbari Brett Roberts Diego Belardi Rakesh Latchamsetty Thomas Crawford Eric Good Krit Jongnarangsin Frank Bogun Aman Chugh Hakan Oral Fred Morady Frank Pelosi 《Heart rhythm》2012,9(12):1964-1968
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Keli D. Coleman Kenneth McKinley Angela M. Ellison Elizabeth R. Alpern Selena Hariharan Irina Topoz Morgan Wurtz Blake Nielsen Lawrence J. Cook Claudia R. Morris Amanda M. Brandow Andrew D. Campbell Robert I. Liem Rachelle Nuss Charles T. Quinn Alexis A. Thompson Anthony Villella Allison A. King Ana Baumann Warren Frankenberger David C. Brousseau 《Pediatric blood & cancer》2023,70(10):e30553
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Natale Andrea Monir George Patel Anshul M. Fishel Robert S. Marchlinski Francis E. Delaughter M. Craig Athill Charles A. Melby Daniel P. Gonzalez Mario D. Hariharan Ramesh Gidney Brett Tan Tiffany Chinitz Larry A. 《Journal of interventional cardiac electrophysiology》2021,61(1):63-69
Journal of Interventional Cardiac Electrophysiology - The prospective, multicenter SMART SF trial demonstrated the acute safety and effectiveness of the 56-hole porous tip irrigated contact force... 相似文献
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Balakrishnan V Unnikrishnan AG Thomas V Choudhuri G Veeraraju P Singh SP Garg P Pai CG Devi RN Bhasin D Jayanthi V Premalatha N Chacko A Kar P Rai RR Rajan R Subhalal N Mehta R Mishra SP Dwivedi M Vinayakumar KR Jain AK Biswas K Mathai S Varghese J Ramesh H Alexander T Philip J Raj VV Vinodkumar A Mukevar S Sawant P Nair P Kumar H Sudhindran S Dhar P Sudheer OV Sundaram KR Tantri BV Singh D Nath TR 《JOP : Journal of the pancreas》2008,9(5):593-600