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排序方式: 共有254条查询结果,搜索用时 31 毫秒
71.
Aksaray G Kortan G Erkaya H Yenilmez C Kaptanoğlu C 《Nordic journal of psychiatry》2006,60(5):387-391
Disasters traumatically expose normal populations to severe threats to life, deaths of relatives and massive environmental destruction. Epidemiological studies found that women would be more vulnerable to disaster than men. In this study, we examined gender differences in short-term psychological effect of the 1999 earthquake in Turkey on adult survivors. A total of 184 subjects (79 males and 105 females) who used a psychiatric service were interviewed within 6-10 weeks after the earthquake. All subjects were assessed using a modified version of the Mississippi Scale for Posttraumatic Stress Disorder, the Beck Depression Inventory, the Beck Hopelessness Scale, and four subscales (depression, anxiety, hostility and somatization) of the Symptom Check List (SCL-90-R). Women had higher mean total Mississippi Scale scores than men (84.29 vs. 78.72; P<0.05). Women scored higher on the Beck Depression Inventory and the Beck Hopelessness Scale than men (respectively 16.3 vs. 10.4; P<0.001 and 7.5 vs. 6.0; P<0.05). Women had significantly higher depression (1.40 vs. 0.94; P<0.001), anxiety (1.46 vs. 1.12; P<0.05) and somatization (1.31 vs. 0.84; P<0.001) subscale scores of the SCL-90-R than men. These findings indicate that women may experience more severe psychological reactions than men after a disastrous earthquake. 相似文献
72.
Mark Otto Baerlocher Murray R Asch Peter Dixon Paul Kortan Andy Myers Calvin Law 《Journal l'Association canadienne des radiologistes》2008,59(3):107-122
OBJECTIVE: To provide evidence-based guidelines regarding the appropriate use of gastrointestinal stents for oncologic indications. This document describes the use of gastrointestinal stents by appropriately trained physicians. METHODS: This document is based on a review of the published evidence and supplemented by consensus expert opinion. Gastrointestinal stenting has been evaluated in terms of technical success, complications, patient satisfaction, clinical outcome, and cost-benefit analysis. This document was approved by the Canadian Interventional Radiology Association; approval from the other relevant Canadian societies is pending. CONCLUSION: Gastrointestinal stenting has a valuable role in the management of gastrointestinal malignancy. The decision to use such devices should be taken after comprehensive multidisciplinary clinical, endoscopic, and radiologic evaluation. 相似文献
73.
In a patient with a mid-common bile duct stone, the traction wires of a mechanical lithotriptor snapped, resulting in lithotriptor basket impaction. Simultaneous occurrence of these two potential complications of endoscopic stone extraction is very rarely reported. Extracorporeal shock wave lithotripsy failed to fragment the stone entrapped within the impacted basket. Endoscopic intracorporeal electrohydraulic shock wave lithotripsy successfully fragmented the stone under direct visualization through a cholangioscope. The entrapped stone within the basket could subsequently be pulled into the supra-ampullary bile duct for the final fragmentation with an extra-endoscopic mechanical lithotriptor cable. The present report is the first to describe a safe and effective use of endoscopic intracorporeal electrohydraulic shock wave lithotripsy followed by extra-endoscopic mechanical lithotripsy in the management of an impacted lithotriptor basket. 相似文献
74.
Methyl-hydroxylated metabolites of the potent carcinogen, 7,12-
dimethylbenz[a]anthracene (DMBA), namely, 7-hydroxymethyl-12-
methylbenz[a]anthracene (7-OH-DMBA), 7-methyl-12-
hydroxymethylbenz[a]anthracene (12-OH-DMBA) and 7,12-
dihydroxymethylbenz[a]anthracene (7,12-diOH-DMBA), were examined as
substrates for sulfotransferase bioactivation in different human tissue
cytosols. Hepatic cytosols, which were able to catalyze the 3'-
phosphoadenosine 5'-phosphosulfate (PAPS)-dependent DNA binding of 7-OH-
DMBA, 12-OH-DMBA and 7,12-diOH-DMBA, were highly sensitive to inhibition by
dehydroepiandrosterone (DHEA), a specific substrate for human DHEA-steroid
sulfotransferase (IC50 = 5 microM). By comparison,
2,6-dichloro-4-nitrophenol, a potent inhibitor of the thermostable (TS)-
phenol and estrogen sulfotransferases, did not have an appreciable
inhibitory effect. Neither p-nitrophenol, a high affinity substrate for
human TS-phenol and estrogen sulfotransferases, nor dopamine, a specific
substrate for the thermolabile (TL)-phenol sulfotransferase, significantly
inhibited the DNA binding of 12-OH-DMBA catalyzed by hepatic cytosols.
Inter-subject variation (n = 12) of the PAPS- dependent DNA binding of
12-OH- and 7,12-diOH-DMBAs also correlated well with DHEA-sulfotransferase
activity (r = 0.90; P < 0.00001 and r = 0.92; P < 0.00001,
respectively). This sulfation-dependent metabolic activation was not
detected in cytosols from human colon, pancreas, larynx or mammary gland.
Both TS- and TL-phenol sulfotransferases were active in human liver and
colon but only liver contained DHEA- sulfotransferase activity. These
results indicate that the sulfotransferase-mediated activation of the
methyl-hydroxylated DMBAs is predominantly catalyzed by DHEA-steroid
sulfotransferase in human liver and that TS- and TL-phenol
sulfotransferases and estrogen sulfotransferase are not involved in the
catalysis.
相似文献
75.
76.
77.
Background : A retrospective assessment of contrast enhanced computed tomography (CECT) scan findings in histopathologically proven cases of carcinoma of the gallbladder (GB) was performed to review its role in diagnosis, staging and assessment of surgical resectability. 相似文献
78.
Bourke MJ Elfant AB Alhalel R Scheider D Kortan P Haber GB 《Gastrointestinal endoscopy》2000,52(4):494-499
BACKGROUND: "Sphincterotomy stenosis" is a recognized late complication of endoscopic biliary sphincterotomy. The narrowing is limited to the biliary orifice and can be managed simply by repeat sphincterotomy. A similar but poorly characterized post-sphincterotomy complication involves narrowing that extends from the biliary orifice for a variable distance along the bile duct, beyond the duodenal wall. This lesion cannot be managed by repeating the sphincterotomy. METHODS: Six patients (3 men) are described with sphincterotomy associated biliary strictures, all smooth and high grade, presenting at a median of 19 months (range 8 to 60 months) after sphincterotomy. Further sphincterotomy was not possible as an intra-duodenal segment of bile duct was no longer visible. Endoscopic management consisted of serial incremental stent exchange at 2- to 4-month intervals. The goal of therapy was to place two 11.5F stents side-by-side. RESULTS: Stricture resolution was documented by cholangiography in all patients. One patient with a stricture resistant to treatment required three 10F stents side-by-side, and another underwent treatment to a maximum of adjacent 11.5F and 7F stents. Two 11.5F stents were eventually placed in the other four patients. Overall median duration of stent placement was 12.5 months. At a median of 26.5 months of stent-free follow-up, all patients remain asymptomatic. CONCLUSION: Sphincterotomy-associated biliary strictures are a distinct late complication of biliary sphincterotomy. These recalcitrant lesions are not amenable to repeat sphincterotomy; however, the results of this study suggest that they may be managed successfully by serial placement of stents of incrementally increasing diameter. 相似文献
79.
80.
GS Chopra RM Gupta SR Gedela PP Varma R Rai SK Nema 《Medical Journal Armed Forces India》2005,61(3):241-244