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71.
Keren Weltman Michal Lavidor 《Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale》2013,226(1):121-135
Here we aim to evaluate the ability of transcranial direct current stimulation (tDCS), which is applied over Wernicke’s area and its right homologue, to influence lexical decisions and semantic priming and establish an involvement for temporo-parietal areas in lexical and semantic processing. Thirty-two subjects (17 women) completed a lexical decision task and a semantic priming task while receiving 20 min of bilateral tDCS stimulation (right anodal/left cathodal or left anodal/right cathodal stimulation) or sham stimulation. We hypothesized that right anodal/left cathodal stimulation over temporo-parietal areas would selectively interrupt the typical lexical processing dominance of the left hemisphere and facilitate mediated priming, while left anodal/right cathodal stimulation would selectively facilitate lexical processing and direct priming. Results showed impaired lexical processing under right anodal/left cathodal stimulation in comparison with sham and left anodal/right cathodal stimulation. Results are discussed in light of previous findings and hemispheric lateralization models. 相似文献
72.
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74.
Moshe E. Stein Keren Drumea Ofer Ben-Itshak Aharon Hoffman Abraham Eyal Boaz Moshkovitz Nissim Haim 《Pediatric blood & cancer》1995,25(2):126-129
Arterial tumor embolization is a rare but serious complication of neoplastic disease. The majority of these tumors are associated with primary or secondary lung malignancies, originating from pulmonary vein metastasis or from an atrial mass. Malignant germ cell tumors primarily disseminate to the retroperitoneal lymph nodes and lung, and to the brain and liver later in the course of the disease. A germ cell tumor metastasis embolizing to the iliac-femoral arterial system has not yet been reported. We report a metastatic embolism in a patient with disseminated embryonal cell carcinoma causing acute limb ischemia, managed by surgical embolectomy. The sudden development of limb ischemia in a patient with a germ cell tumor should alert the physician to the possibility of tumor embolism. © 1995 Wiley-Liss, Inc. 相似文献
75.
Cyanosis, clubbing, and arterial oxygen desaturation may occur in patients with liver disease, and are attributed to the presence of pulmonary or peripheral arterio-venous shunting. Cardiac catheterisation and angiocardiography in a patient with a normal heart did not demonstrate the presence of abnormal arterio-venous anastomoses. Pulmonary shunting was proved when intravenous technetium-labelled macroaggregated albumin, normally held up in capillary networks, was passed quickly through the lungs and immediately detected in high systemic blood flow organs. The opening of peripheral and pulmonary anastomoses in patients with liver disease may be owing to the presence of a vasodilatory substance such as ferritin, which was found to be abnormally increased in the patient's blood. 相似文献
76.
Silverberg DS Wexler D Blum M Tchebiner J Sheps D Keren G Schwartz D Baruch R Yachnin T Shaked M Zubkov A Steinbruch S Iaina A 《Clinical nephrology》2002,58(Z1):S37-S45
Both Congestive Heart Failure (CHF) and Chronic Renal Failure (CRF) are increasing steadily in the community. We propose that there is a vicious circle established whereby CHF and CRF both cause anemia and the anemia then worsens both the CHF and CRF causing more anemia and so on. We call this the Cardio Renal Anemia (CRA) syndrome. By the combination of active treatment of the CHF and control of the anemia with subcutaneous erythropoietin and intravenous iron, the progression of both the CHF and the CRF can be slowed or stopped in most cases, the quality of life improved and the need for recurrent hospitalization reduced. This will involve cooperation between internists, cardiologists, and nephrologists to allow early and maximal therapy of both the CHF and the anemia. 相似文献
77.
Nada-Raja S Morrison D Skegg K 《The Australian and New Zealand journal of psychiatry》2003,37(5):600-605
OBJECTIVE: To examine help-seeking for self-harm in a population-based sample of young adults. METHOD: Nine hundred and sixty-five participants aged 26 years were interviewed about help-seeking and barriers to help-seeking for a range of self-harmful behaviours. Self-harm included the traditional methods of suicide (ICD-9 self-harm) and other self-harmful behaviours such as self-battery and self-biting. RESULTS: Just over half of the 25 in the ICD-self-harm group (based on ICD-9 self-harm criteria) and one-fifth of the 119 in the other self-harmful behaviour group had sought professional help. Counsellors, psychologists, and general practitioners were the commonest sources of help. Most participants rated help received from health services favourably, however, emergency services were rated less favourably than other health services. Among 77 self-harm participants who did not seek help, just over one-third reported attitudinal barriers. CONCLUSIONS: To encourage help-seeking by young adults who self-harm, especially young men who are at high risk for self-harm and suicide, it may be necessary to identify ways to reduce attitudinal barriers. 相似文献
78.
Ferraro M Demaio JH Krol J Trudell C Rannekleiv K Edelstein L Christos P Aisen M England J Fasoli S Krebs HI Hogan N Volpe BT 《Neurorehabilitation and neural repair》2002,16(3):283-289
The Motor Status Scale (MSS) measures shoulder, elbow (maximum score = 40), wrist, hand, and finger movements (maximum score = 42), and expands the measurement of upper extremity impairment and disability provided by the Fugl-Meyer (FM) score. This work examines the interrater reliability and criterion validity of the MSS performed in patients admitted to a rehabilitation hospital 21 +/- 4 days after stroke. Using the MSS and the FM, 7 occupational therapists masked to each other's judgments, evaluated 12 consecutive patients with stroke. Two therapists evaluated 6 additional patients on consecutive days. Intraclass correlation coefficients were significant for each group of raters for the shoulder/elbow and for the wrist/band (P < 0.0001); test-retest measures were also significant for the shoulder/elbow (Pearson correlation coefficient r = 0.99, P < 0.004) and for the wrist/hand (Pearson correlation coefficient r = 0.99, P < 0.003). The internal item consistency for the overall MSS was significant (Cronbach alpha = 0.98, P < 0.0001). Finally the correlation between the MSS and the FM (R2 = 0.964) was significant (P < 0.0001). The MSS affords a reliable and valid assessment of upper limb impairment and disability following stroke. 相似文献
79.
目的观察榄香烯(Ele)、姜黄素(Cur)对体外培养的牛晶状体上皮细胞(LECs)凋亡的超微结构的影响。方法分别用160μg/mlEle,20μg/ml Cur与LECs共同孵育24、48、72h,采用透射电子显微镜观察LECs超微结构的变化。结果Ele和Cur作用不同时间的LECs均出现核染色质凝集、固缩、边集等典型的凋亡形态学改变,呈时一效依赖关系。超微结构研究显示,Cur诱导凋亡的同时,也诱导发生细胞胀亡。结论Ele和Cur具有明显诱导LECs凋亡或胀亡的作用。 相似文献
80.
The postoperative period is associated with neuroendocrine, metabolic, and immune alterations, which are the combined result of tissue damage, anesthesia, postoperative pain, and psychological stress. Limited evidence indicates that pain management in the postoperative period can affect the outcome of the surgery, reducing cardiac, pulmonary, and metabolic complications. Recent evidence indicates that pain and immune factors, especially proinflammatory cytokines, mutually interact and influence each other. A series of animal studies demonstrates that effective preemptive analgesia improved postoperative recovery, and this effect was enhanced by coadministration of IL-1ra together with the preemptive analgesics. Furthermore, preemptive analgesia attenuated surgery-induced PGE2 production in the amygdala and the activation of the HPA axis. IL-1 signaling is required for the production of amygdala PGE2 in response to surgical stress, and may thus affect the physiological and psychological aspects of surgical stress. These reports suggest that short-term effective analgesia can have long-lasting beneficial effects on surgery recovery. They further suggest that IL-1 blockade should be considered in the clinical management of pain associated with peripheral or nerve injury. Another series of human studies describes an interaction between the effectiveness of postoperative pain relief and surgery-associated immune alterations: In three separate studies, the more effective pain management technique was associated with diminished surgery-induced immune alterations, especially diminished elevation of IL-1. Reduced elevation of postoperative IL-1 and effective pain relief may both contribute to an attenuated illness response and a better surgery outcome.Presented at the 12th SNIP Conference, Santa Fe, New Mexico, April 5–9, 2006. 相似文献