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651.
Idiopathic hypogonadotrophic hypogonadism (IHH) is a potentially
correctable cause of male infertility. However hormonal treatment is
usually a slow process and artificial reproductive techniques such as
intracytoplasmic sperm injection (ICSI) might be resorted to before full
testicular response has been achieved. We report here an unusual variant of
IHH of post-pubertal onset in which early intervention with ICSI was
attempted. Our patient was 37 years old and presented with male infertility
due to azoospermia and undetectable serum gonadotrophin concentrations. He
had an apparently normal pubertal development, a testicular volume of 8 ml,
normal pituitary-thyroid and pituitary-adrenal function, as well as normal
computerized tomographic appearance of the sella region. A combination of
human chorionic gonadotrophin (HCG) and menopausal gonadotrophins (HMG) was
administered. Spermatozoa were first detected in the semen after 3 months
and reached a concentration of approximately 2x10(6)/ml after 9 months.
ICSI was attempted at this point; the spermatozoa had good fertilizing
ability and three embryos were obtained and replaced. Unfortunately no
pregnancy resulted. Treatment with 5000 IU HCG and 150 IU HMG three times
per week was continued and sperm counts rose rapidly thereafter to reach
28.3x10(6)/ml after 16 months of injections. His wife conceived naturally
during this period and the pregnancy is now in the second trimester. This
case illustrates the good prognosis of the rare patient with IHH of
post-pubertal onset when treated with gonadotrophins, and suggests that
ICSI procedures should be delayed until final testicular maturation is
attained.
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A Garg V Gupta S Gaikwad P Deol NK Mishra A Suri SS Kale 《Journal of Medical Imaging and Radiation Oncology》2003,47(2):194-197
We report two cases of lumbar spinal dermoid cysts with asymptomatic rupture and migration of free fat droplets into the central canal. No fatty droplets were seen within the lumbar subarachnoid space. The presence of fat droplets within the central canal is unusual because the central canal is rudimentary in adults. We suggest that hydromyelia secondary to tumour and specific tumour morphology might facilitate the selective rupture of dermoids into the central canal. We recommend a follow up of these patients to detect any possible intracranial migration of fat droplets and resultant complications. 相似文献
655.
Winnie KW So PhD RN Gigi CC Ling MN RN Kai‐chow Choi PhD Carman WH Chan PhD RN Rayman WM Wan MN RN Suzanne SS Mak MN RN Janet WH Sit PhD RN 《International journal of nursing practice》2013,19(3):306-317
The purpose of this study is to compare health‐related quality of life (HRQoL) and emotional distress among diverse cancer survivors who had completed all treatment within the previous year. A convenience sample of 353 cancers survivors (lung, head and neck, breast and prostate cancers) were recruited to complete a survey, which consisted of (i) Hospital Anxiety and Depression Scales; (ii) Chinese version of the Functional Assessment of Cancer Therapy—General version; and (iii) demographic and clinical data. The HRQoL scores were similar among the four types of survivors. Mild anxiety and depression levels were reported, but no significant difference was noted. Younger females with financial burdens and uncertain prognosis were particularly associated with HRQoL and emotional distress. Further studies are essential to identify specific problems that cancer patients experience after cancer diagnosis that might lead to the early detection of those most at risk of ongoing problems. 相似文献
656.
目前,随着糖尿病患者的增加,糖尿病胃肠并发症越来越常见,这些并发症及其症候通常是由胃肠运动异常引起,常与胃肠道神经病变相关。有研究表明,糖尿病自发神经病变与糖尿病的持续时间有关,但糖尿病控制及并发症的临床试验表明,1型糖尿病患者其神经和胃肠并发症与血糖控制不良有关,与患者持续时间并无必然联系。糖尿病引发的胃肠异常通常可见胃轻瘫、肠下垂(可导致腹泻、便秘和排便失禁)以及非酒精性脂肪肝。 相似文献
657.
Transient osteoporosis of hip is a condition of unknown etiology, presenting as painful limping, and characterized by osteopenia of the involved joint without preexisting disease or immobilization. Most of the cases were reported in middle-aged men, and one-third of the cases develop in women in the third trimester of pregnancy. The hypothesis that this condition leads to avascular necrosis of the hip has been disproved by various reports and hence does not warrant any surgical interference. This is a self limiting condition, which needs regular follow-up. The authors report a case of migrating transient osteoporosis of the hip in a 30-year-old man successfully treated with antiresorptive treatment. 相似文献
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