全文获取类型
收费全文 | 2581篇 |
免费 | 178篇 |
国内免费 | 22篇 |
专业分类
耳鼻咽喉 | 17篇 |
儿科学 | 66篇 |
妇产科学 | 61篇 |
基础医学 | 453篇 |
口腔科学 | 65篇 |
临床医学 | 153篇 |
内科学 | 532篇 |
皮肤病学 | 36篇 |
神经病学 | 178篇 |
特种医学 | 79篇 |
外科学 | 399篇 |
综合类 | 134篇 |
一般理论 | 1篇 |
预防医学 | 160篇 |
眼科学 | 44篇 |
药学 | 197篇 |
中国医学 | 23篇 |
肿瘤学 | 183篇 |
出版年
2023年 | 25篇 |
2022年 | 52篇 |
2021年 | 75篇 |
2020年 | 39篇 |
2019年 | 69篇 |
2018年 | 58篇 |
2017年 | 52篇 |
2016年 | 75篇 |
2015年 | 102篇 |
2014年 | 175篇 |
2013年 | 162篇 |
2012年 | 210篇 |
2011年 | 228篇 |
2010年 | 136篇 |
2009年 | 115篇 |
2008年 | 144篇 |
2007年 | 142篇 |
2006年 | 138篇 |
2005年 | 103篇 |
2004年 | 94篇 |
2003年 | 96篇 |
2002年 | 70篇 |
2001年 | 53篇 |
2000年 | 38篇 |
1999年 | 52篇 |
1998年 | 18篇 |
1997年 | 15篇 |
1996年 | 17篇 |
1995年 | 13篇 |
1994年 | 14篇 |
1993年 | 5篇 |
1992年 | 25篇 |
1991年 | 22篇 |
1990年 | 13篇 |
1989年 | 17篇 |
1988年 | 13篇 |
1987年 | 12篇 |
1986年 | 12篇 |
1985年 | 12篇 |
1984年 | 11篇 |
1982年 | 5篇 |
1981年 | 4篇 |
1975年 | 5篇 |
1973年 | 4篇 |
1971年 | 3篇 |
1970年 | 3篇 |
1969年 | 3篇 |
1968年 | 5篇 |
1966年 | 4篇 |
1965年 | 3篇 |
排序方式: 共有2781条查询结果,搜索用时 249 毫秒
71.
Ohnishi in 1975 first described temporomandibular joint (TMJ) arthroscopy. Along with its extensive use, a range of complications has emerged. We describe a patient who experienced parapharyngeal swelling after undergoing arthroscopy. Prolonged intubation up to 1 hour postoperatively was required. The swelling resolved completely over 6 h without further intervention. 相似文献
72.
Differentiating hepatic portal venous gas (HPVG) and pneumobilia on the CT scan can be accomplished by comparing the pattern of intrahepatic air spread. HPVG can be an indicator of significant intra‐abdominal pathology and bowel ischaemia is the most common causative etiology for HPVG. 相似文献
73.
Benjamin Poh Paul Cashin Kaye Bowers Travis Ackermann Yeng Kwang Tay Arun Dhir Daniel Croagh 《HPB : the official journal of the International Hepato Pancreato Biliary Association》2014,16(7):629-634
Introduction
Minimally-invasive options for the management of choledocholithiasis in patients undergoing laparoscopic cholecystectomy include laparoscopic and endoscopic approaches. This study reviews the effectiveness of both approaches in an emergency setting.Methods
A retrospective chart review was performed for a cohort of patients who underwent laparoscopic cholecystectomy. Outcomes assessed were duct clearance, the number of procedures performed (NPP), length of stay (LOS) and complication rate.Results
A total of 182 patients who underwent emergency laparoscopic cholecystectomies received intervention for choledocholithiasis. The duct clearance rate was lower in the laparoscopic group, 63% versus 86% (P = 0.001). However, the median NPP was also lesser in the laparoscopic group, 1 (interquartile range (IQR) 1–2) versus 2 (IQR 2–2) (P < 0.001), as was the median LOS, 5 days (IQR 3–8) versus 7 days (IQR 6–10) (P = 0.009). Forty-eight laparoscopic endobiliary stents were attempted; stent deployment was successful in 37 patients. A larger proportion of patients with laparoscopic endobiliary stents had duct clearance by endoscopic retrograde cholangiopancreatography (ERCP) compared with those without, although this was not statistically significant (P = 0.208).Conclusion
Laparoscopic clearance is not as effective as post-operative ERCP in an emergency cohort, but is associated with fewer procedures required and a shorter inpatient stay. Thus, laparoscopic clearance may still be an attractive option for surgeons especially where conditions are favourable during an emergency laparoscopic cholecystectomy. 相似文献74.
Pradeep Kumar Sharma Bhaskar Saikia Rachna Sharma Kumar Ankur Praveen Khilnani Vinay Kumar Aggarwal Hae Cheong 《Indian journal of pediatrics》2014,81(10):1095-1098
Bartter syndrome is a group of inherited, salt-losing tubulopathies presenting as hypokalemic metabolic alkalosis with normotensive hyperreninemia and hyperaldosteronism. Around 150 cases have been reported in literature till now. Mutations leading to salt losing tubulopathies are not routinely tested in Indian population. The authors have done the genetic analysis for the first time in the Bartter syndrome on two cases from India. First case was antenatal Bartter syndrome presenting with massive polyuria and hyperkalemia. Mutational analysis revealed compound heterozygous mutations in KCNJ1(ROMK) gene [p(Leu220Phe), p(Thr191Pro)]. Second case had a phenotypic presentation of classical Bartter syndrome however, genetic analysis revealed only heterozygous novel mutation in SLC12A gene p(Ala232Thr). Bartter syndrome is a clinical diagnosis and genetic analysis is recommended for prognostication and genetic counseling. 相似文献
75.
Yong Sang Lee Hyunsun Lim Hang-Seok Chang Cheong Soo Park 《Journal of Korean medical science》2014,29(5):676-679
The aim of this study was to review the literature of latent papillary thyroid carcinomas (PTCs) discovered at autopsy and describe the available pathologic and demographic differences from a group of papillary thyroid microcarcinomas (PTMCs) the reported in a previous publication. We searched the PubMed for published articles describing latent thyroid carcinomas detected at autopsy. Meta-analysis was performed to identify differences between the clinicopathologic features of PTMCs analyzed previously in our institution (Group I) and those of latent PTCs described in autopsy studies (Group II). We identified 1,355 patients with PTMC (Group I) and 989 with latent PTCs (Group II). Mean patient age was 47.3 yr in Group I and 64.5 yr in Group II. The male:female ratio was 1:10.9 in Group I and 1:1 in Group II. Most PTMCs (67.6%) were larger than 0.5 cm in size, whereas most latent PTCs were <1-3 mm in diameter. The rates of multifocality were 24.7% in Group I and 30.5% in Group II, and the rates of cervical lymph node metastasis were 33.4% in Group I and 10.0% in Group II. Currently available data indicated that clinically evident PTMCs differ from latent PTCs detected at autopsy. Therefore, these two entities should be regarded as different. 相似文献
76.
Jae Youn Cheong Hyoung Doo Shin Sung Won Cho Yoon Jun Kim 《Journal of Korean medical science》2014,29(11):1523-1527
MicroRNA polymorphisms may be associated with carcinogenesis or immunopathogenesis of infection. We evaluated whether the mircoRNA-604 (miR-604) polymorphism can affect the persistence of hepatitis B virus (HBV) infection, and the development to hepatocellular carcinoma (HCC) in patients with chronic HBV infection. A total of 1,439 subjects, who have either past or present HBV infection, were enrolled and divided into four groups (spontaneous recovery, chronic HBV carrier without cirrhosis, liver cirrhosis and HCC). We genotyped the precursor miR-604 genome region polymorphism. The CC genotype of miR-604 rs2368392 was most frequently observed and T allele frequency was 0.326 in all study subjects. The HBV persistence after infection was higher in those subjects with miR-604 T allele (P=0.05 in a co-dominant and dominant model), which implied that the patients with miR-604 T allele may have a higher risk for HBV chronicity. In contrast, there was a higher rate of the miR-604 T allele in the chronic carrier without HCC patients, compared to those of the HCC patients (P=0.03 in a co-dominant model, P=0.02 in a recessive model). The T allele at miR-604 rs2368392 may be a risk allele for the chronicity of HBV infection, but may be a protective allele for the progression to HCC in chronic HBV carriers.
Graphical Abstract
相似文献77.
78.
79.
80.
Manoel J. Teixeira Massako Okada Ana Sofia Cueva Moscoso Mariana Yumi Takahashi Puerta Lin T. Yeng Ricardo Galhardoni Sérgio Tengan Daniel Ciampi de Andrade 《Clinics (S?o Paulo, Brazil)》2013,68(7):1057-1060