Influences of Heavy Metals and Salt on Seed Germination and Seedling Characteristics of Halophyte Halogeton glomeratus

Bulletin of Environmental Contamination and Toxicology - Heavy metals pollution and salinization of soils are widely distributed in agricultural soils. This study investigated the effects of five...     

Occurrence,Human Exposure,and Risk Assessment of Polybrominated Dibenzo-p-Dioxins and Dibenzofurans,Polychlorinated Naphthalenes,and Metals in Atmosphere Around Industrial Parks in Jiangsu,China

Air samples were collected around industrial parks in Jiangsu, China, to allow the concentrations, profiles, and risk assessment of polybrominated dibenzo-p-dioxins and dibenzofurans (PBDD/Fs), polychlorinated naphthalenes (PCNs), and metals to be investigated. The concentrations of ΣPBDD/Fs and ΣPCNs were 1324.26–2080.98 fg/m³ (11.35–42.57 fg I-TEQ/m³) and 10,404.9–29,322.9 fg/m³ (1.32–7.19 fg I-TEQ/ m³), respectively. The highest concentration of ΣPBDD/Fs and ΣPCNs were observed at site C. PBDD/Fs were mainly dominated by PBDFs. The main contributor to the ΣPBDD/Fs in all samples was 1,2,3,4,6,7,8-HpBDF, which accounted for 25.75%–39.4%. For PCNs, the predominating homologues were tetra-, tri- and penta-CNs, which contributed 30.7%–43.3%, 24.7%–31.0%, and 10.6%–21.6%, respectively. As for metals, the pollution of As, Mn, Cr, and Ni in most samples exceeded National Ambient Air Quality Standards of China. Assessing the risk of inhalation exposure showed that there were potential carcinogenic risks to local residents.

     

肾上腺髓质微血管构筑

本文以树脂铸型扫描电镜法,观察大鼠和小鼠肾上腺髓质的微血管构筑,并特别注意髓质血管和皮质血管的相互关系;此外切片观察测量了肾上腺髓质两种嗜铬细胞的分布。肾上腺皮质集合小静脉发出侧支,分布于髓质,构成了门静脉循环特点。小鼠的肾上腺髓质,主要由这种侧支供应;而大鼠的髓质,还有多支髓质动脉供应。从血管铸型上表现出的明显局部环形缩窄推测,肾上腺髓质血液循环有若干括约装置控制。大、小鼠两种嗜铬细胞在肾上腺髓质内的分布不同,大鼠的呈随机分布;小鼠的 NA 细胞多靠近皮质,而 A 细胞多远离皮质。     

Acupoint-specific fMRI patterns in human brain

Specific central nervous system (CNS) responses to acupuncture have recently attracted attention. It is important to understand the differences in fMRI images of the brain evoked by acupuncture at an acupoint and at a nearby "sham" point. Here, we report analyses of fMRI images of the brains of 37 healthy volunteers in response to acupuncture at Liv3 (Taichong) and LI4 (Hegu) versus their sham points. We found common activation areas in response to Liv3 or LI4 acupuncture in the middle temporal gyrus and cerebellum, along with deactivation areas in the middle frontal gyrus and inferior parietal lobule, compared with the effects of acupuncture at sham points. Acupuncture at Liv3 evoked specific activation at the postcentral gyrus, posterior cingulate, parahippocampal gyrus, BA 7, 19 and 41, but deactivation at the inferior frontal gyrus, anterior cingulate, BA 17 and 18, compared with acupuncture at its sham point. Acupuncture at LI4 evoked specific activation at the temporal pole, but deactivation at the precentral gyrus, superior temporal gyrus, pulvinar and BA 8, 9 and 45, compared with acupuncture at its sham point. These observations reveal that acupuncture at acupoints induces specific patterns of brain activity, and these patterns may relate to the therapeutic effects of acupuncture.     

一种基于独立成分分析的功能磁共振数据处理方法

独立成分分析（ICA）是统计信号处理中的一项新技术，用来从混合信号的多维观测中提取具有统计独立性的成分。我们针对功能磁共振数据处理，采用先对相邻的两体元信号作ICA分离，然后与参考信号进行相关，把相关系数大于一定阈值的体元作为刺激引起兴奋的体元，从而实现刺激的功能定位。经实际脑功能磁共振数据试验，初步证明了方法的有效性。     

Histopathological features of congenital fundus lesions in familial adenomatous polyposis

We report the light and electron microscopic findings for two lesions from two patients who died of complications of familial adenomatous polyposis. In the first case microscopy of a small (100 to 200 mu), uniformly dark lesion (the commonest type seen in this condition) showed enlarged retinal pigment epithelial cells with an increased number of pigment granules. This is consistent with the term "hypertrophy of the retinal pigment epithelium", currently used to describe these lesions. In the second case we sectioned a larger (1000 to 1500 mu), oval, grey lesion from the posterior pole. The pigment epithelium was normal, but between it and outer retina was an unusual choristoma consisting largely of myelinated axons and astrocytes.     

Expression and function of c-kit receptor in bone marrow mononuclear cells of patients with myelodysplastic syndromes

目的　了解骨髓增生异常综合征 (MDS)骨髓单个核细胞c kit受体的表达与功能。方法　采用免疫荧光方法测定c kit受体蛋白 (CD117)的表达 ;逆转录 聚合酶链反应方法测定c kitmRNA的表达 ;细胞培养检测c kit受体的功能。结果　CD117表达率正常人为 3 0 4 %± 1 4 9% ,MDS患者为 8 58%± 5 2 8% ,两者差异有显著性 (P <0 0 5) ;RA患者为 5 12 %± 2 13% ) ,RAEB RAEB t患者为 10 0 1%± 5 0 7% ,两者差异有显著性 (P <0 0 5) ;MDS继发白血病患者为 32 4 3%± 18 16 %。MDS患者c kit基因mRNA表达与CD117表达相一致。正常骨髓单个核细胞体外半固体培养 ,在加入造血干细胞因子、白细胞介素 3、红细胞生成素 (SCF IL 3 Epo)后形成的粒 巨噬细胞集落 (CFU GM)较仅加入IL 3 Epo显著增多 (P <0 0 5) ,红系爆式集落 (BFU E)数量极显著增多 ,且BFU E体积显著增大(P <0 0 1)。MDS患者在上述相同条件下CFU GM数量无明显变化 (P >0 0 5) ,与正常对照比较 ,CFU GM和BFU E数量均显著减少 (P <0 0 5)。结论　MDS患者骨髓单个核细胞CD117表达明显高于正常对照 ,且与病情进展相关 ;c kitmRNA表达与CD117表达相一致 ;MDS患者骨髓单个核细胞体外培养时 ,SCF协同IL 3、Epo促进造血干 祖细胞增殖分化能力较正常对照明     

顺铂术中腹腔化疗对妇科恶性肿瘤患者术后的近期影响

目的 探讨顺铂术中腹腔化疗治疗妇科恶性肿瘤的可行性。方法 60例妇科恶性肿瘤患者术中腹腔置入100mg顺铂稀释液,观察其对患者术后胃肠功能、体温、切口愈合、腹水控制及术后并发症的影响。结果 术后24h内呕吐发生率增高,但使用止吐剂及水化效果好,尿量达标;胃肠道功能按期恢复;术后发热发生率低;服务部切口无一例丙级愈合;无并发症发生。14例伴发大量腹水患者11例得到控制。肝肾功能未发现损害。结论 术中腹腔化疗比较安全,切实可行。     

小脑和脑干梗塞致突发性耳聋

目的:了解小脑和脑干梗塞引起的突发性耳聋的临床特点.探讨其发病机制.方法:回顾性分析12例小脑和脑干梗塞所致突发性耳聋的临床资料.结果:该组患者主要临床表现为耳聋、眩晕、耳鸣、眼震、同侧颜面麻木感.头颅CT或MRI发现小脑或脑干有小于2 cm的梗塞灶.结论:发病机制主要为小脑前下动脉(AlCA)供血不足使小脑脑桥角或脑干缺血,损伤该区域的耳蜗神经和听神经传导通路,导致耳聋.小脑和脑干梗塞的诊断主要依据临床表现、CT或MRI检查.     

重组人白细胞介素-13对巨核细胞系-Dami细胞原癌基因c-mpl表达的影响

目的:研究重组人白细胞介素-13(rhIL-13)对巨核细胞系-Dami细胞原癌基因c-mpl表达的影响.方法:实验组细胞培养系统中分别加入25 ng/ml,50 ng/ml,100ng/ml rhIL-13,对照组不加任何细胞因子.用RT-PCR法检测c-mpl mRNA的表达.结果:经25 ng/ml、50 ng/ml、100ng/ml rhIL-13处理过的实验组Dami细胞较之对照组其c-mpl mRNA的表达分别提高24.8%、27.9%和31.5%.结论:rhIL-13增强了Dami细胞原癌基因c-mpl表达;rhIL-13促进Dami细胞增殖的部分机制可能是通过上调c-mpl的表达来实现的.