全文获取类型
收费全文 | 2710篇 |
免费 | 134篇 |
国内免费 | 24篇 |
专业分类
耳鼻咽喉 | 77篇 |
儿科学 | 84篇 |
妇产科学 | 140篇 |
基础医学 | 236篇 |
口腔科学 | 105篇 |
临床医学 | 227篇 |
内科学 | 589篇 |
皮肤病学 | 64篇 |
神经病学 | 195篇 |
特种医学 | 96篇 |
外科学 | 538篇 |
综合类 | 41篇 |
一般理论 | 1篇 |
预防医学 | 88篇 |
眼科学 | 112篇 |
药学 | 106篇 |
中国医学 | 3篇 |
肿瘤学 | 166篇 |
出版年
2024年 | 8篇 |
2023年 | 21篇 |
2022年 | 29篇 |
2021年 | 46篇 |
2020年 | 35篇 |
2019年 | 54篇 |
2018年 | 57篇 |
2017年 | 69篇 |
2016年 | 86篇 |
2015年 | 101篇 |
2014年 | 127篇 |
2013年 | 160篇 |
2012年 | 204篇 |
2011年 | 222篇 |
2010年 | 111篇 |
2009年 | 108篇 |
2008年 | 194篇 |
2007年 | 248篇 |
2006年 | 201篇 |
2005年 | 187篇 |
2004年 | 137篇 |
2003年 | 116篇 |
2002年 | 101篇 |
2001年 | 45篇 |
2000年 | 49篇 |
1999年 | 27篇 |
1998年 | 9篇 |
1997年 | 11篇 |
1996年 | 10篇 |
1995年 | 3篇 |
1993年 | 2篇 |
1992年 | 8篇 |
1991年 | 8篇 |
1990年 | 6篇 |
1989年 | 6篇 |
1988年 | 4篇 |
1987年 | 4篇 |
1986年 | 2篇 |
1985年 | 2篇 |
1984年 | 2篇 |
1982年 | 4篇 |
1981年 | 6篇 |
1979年 | 2篇 |
1978年 | 2篇 |
1977年 | 3篇 |
1973年 | 4篇 |
1972年 | 5篇 |
1970年 | 5篇 |
1968年 | 2篇 |
1967年 | 3篇 |
排序方式: 共有2868条查询结果,搜索用时 15 毫秒
11.
Purpose
To compare the outcomes of percutaneous nephrolithotomy (PCNL) in 2 age groups. 相似文献12.
THE PURPOSE OF THE STUDY: Direct or indirect trauma to the coccygeal bone can induce chronic coccygodynia. The aim of this study is a retrospective analysis of our patients surgically managed for traumatic coccygodynia and a critical review of the results obtained in comparison to the literature. BASIC PROCEDURES: We have retrospectively investigated patients with traumatic coccygodynia referred to our centre after a failure of conservative treatment. Surgery (coccygectomy) was performed in 74 patients (64 women, 10 men) suffering from coccygodynia resistant to conservative treatment, all without serious complications, between the years 1998 and 2004. The mean follow up was 4.1 years (range, 2-8 years). The mean age of patients on the date of surgery was 43.4 years (range, 16-65 years). The average duration of pain prior to surgery was 7 months (range, 3 months to one year). MAIN FINDINGS: All but three patients had either good or excellent results after surgery. Three patients reported postoperative pain lasting 3-6 months. All three had good results after re-operation of a proximal segment without excision. Five postoperative complications, four superficial and one deep infection were observed. PRINCIPAL CONCLUSIONS: In patients with posttraumatic, conservative therapy-resistant coccygodynia, operative treatment with coccygectomy is a feasible management option. We recommend total or partial coccygectomy using a longitudinal incision in carefully selected and well-informed patients. 相似文献
13.
ümit Bilge Dogan Mustafa Salih Akin Serkan Yalaki Atilla Akova Cengiz Yilmaz 《Canadian journal of surgery》2014,57(2):106-111
Background
Intragastric band migration is an unusual but major complication of gastric banding. We review our experience with endoscopic removal of eroded gastric bands.Methods
We retrospectively evaluated the cases of 110 morbidly obese patients who underwent adjustable gastric banding between 2005 and 2012 to identify those who experienced band erosion. To remove the migrated band, we used an endoscopic approach with a Gastric Band Cutter.Results
Band or tube erosion occurred in 14 patients (12.7%). The median time interval from the initial gastric band placement to the diagnosis of band erosion was 32 (range 18–52) months. Upper abdominal pain, port site infection, loss of restriction and weight regain were the most common symptoms. We used the Gastric Band Cutter to remove the band endoscopically. It was able to cut the band successfully in all but 1 patient, in whom twisting of the cutting wire required conversion from endoscopy to laparotomy. In 2 patients, the band, after being cut, was locked in the gastric wall and required laparotomic removal. In 1 patient, we performed surgery for intragastric penetration of the connecting tube broken close to the band.Conclusion
The Gastric Band Cutter was successful in dividing the band in all but 1 patient, although we could not always complete the procedure endoscopically. Endoscopic removal seems to be effective and safe for band erosion. 相似文献14.
15.
Ercan?YeniEmail author Dogan?Unal Ayhan?Verit Omer?Faruk?Karatas 《International urogynecology journal》2004,15(3):212-213
A 39-year-old woman with three children presented with primary severe urinary incontinence. Epispadias without exstrophy was determined in physical examination. The single-stage procedure including vulvoplasty and modified Young-Dees-Leadbetter bladder neck repair was performed to obtain sufficient cosmetic outcome and continence. Excellent functional and cosmetic results were obtained. 相似文献
16.
Ali Konan Umut Kalyoncu Ismail Dogan Yusuf A. Kili? Derya Karako? Ali Akdogan Sedat Kiraz Volkan Kaynaro?lu Demirali Onat 《Breast care (Basel, Switzerland)》2012,7(4):297-301
Background
Idiopathic granulomatous mastitis (IGM) is a rare benign inflammatory disease of the breast. It is related to various etiological factors. The treatment of IGM is challenging as there is a lack of consensus in the literature and treatment options vary widely. Conservative treatment with antibiotics, glucocorticoids and immunosuppressive drugs, and surgery are used in the management of the disease. In this article we report our experience with IGM patients receiving immunosuppressive treatment.Patients and Methods
The medical records of patients with IGM receiving systemic therapy at the Hacettepe University Hospital between October 2007 and May 2010 were reviewed. 15 cases of histopathologically proven IGM were identified. The data was examined for risk factors and success of treatment.Results
14 patients were given prednisolone together with azathioprine, and 1 patient who was pregnant at the time of diagnosis received only prednisolone (30 mg/day). 11 (73%) patients had a complete response to systemic therapy. 2 patients had a relapse, of whom 1 required surgical drainage and 1 was treated with a higher dose of glucocorticoids.Conclusion
Systemic therapy is a safe and effective treatment for IGM. The addition of azathioprine to glucocorticoid therapy permits quick tapering of the steroid doses and increases the treatment success. 相似文献17.
Tekgül S Riedmiller H Hoebeke P Kočvara R Nijman RJ Radmayr C Stein R Dogan HS 《European urology》2012,62(3):534-542
Context
Primary vesicoureteral reflux (VUR) is a common congenital urinary tract abnormality in children. There is considerable controversy regarding its management. Preservation of kidney function is the main goal of treatment, which necessitates identification of patients requiring early intervention.Objective
To present a management approach for VUR based on early risk assessment.Evidence acquisition
A literature search was performed and the data reviewed. From selected papers, data were extracted and analyzed with a focus on risk stratification. The authors recognize that there are limited high-level data on which to base unequivocal recommendations, necessitating a revisiting of this topic in the years to come.Evidence synthesis
There is no consensus on the optimal management of VUR or on its diagnostic procedures, treatment options, or most effective timing of treatment. By defining risk factors (family history, gender, laterality, age at presentation, presenting symptoms, VUR grade, duplication, and other voiding dysfunctions), early stratification should allow identification of patients at high potential risk of renal scarring and urinary tract infections (UTIs). Imaging is the basis for diagnosis and further management. Standard imaging tests comprise renal and bladder ultrasonography, voiding cystourethrography, and nuclear renal scanning. There is a well-documented link with lower urinary tract dysfunction (LUTD); patients with LUTD and febrile UTI are likely to present with VUR. Diagnosis can be confirmed through a video urodynamic study combined with a urodynamic investigation. Early screening of the siblings and offspring of reflux patients seems indicated.Conservative therapy includes watchful waiting, intermittent or continuous antibiotic prophylaxis, and bladder rehabilitation in patients with LUTD. The goal of the conservative approach is prevention of febrile UTI, since VUR will not damage the kidney when it is free of infection. Interventional therapies include injection of bulking agents and ureteral reimplantation. Reimplantation can be performed using a number of different surgical approaches, with a recent focus on minimally invasive techniques.Conclusions
While it is important to avoid overtreatment, finding a balance between cases with clinically insignificant VUR and cases that require immediate intervention should be the guiding principle in the management of children presenting with VUR. 相似文献18.
Turan Olgar Esra Onal Dogan Bor Nurullah Okumus Yildiz Atalay Canan Turkyilmaz Ebru Ergenekon Esin Koc 《Korean journal of radiology》2008,9(5):416-419
OBJECTIVE: The aim of this work was to determine the radiation dose received by infants from radiographic exposure and the contribution from scatter radiation due to radiographic exposure of other infants in the same room. MATERIALS AND METHODS: We retrospectively evaluated the entrance skin doses (ESDs) and effective doses of 23 infants with a gestational age as low as 28 weeks. ESDs were determined from tube output measurements (ESD(TO)) (n = 23) and from the use of thermoluminescent dosimetry (ESD(TLD)) (n = 16). Scattered radiation was evaluated using a 5 cm Perspex phantom. Effective doses were estimated from ESD(TO) by Monte Carlo computed software and radiation risks were estimated from the effective dose. ESD(TO) and ESD(TLD) were correlated using linear regression analysis. RESULTS: The mean ESD(TO) for the chest and abdomen were 67 microGy and 65 microGy per procedure, respectively. The mean ESD(TLD) per radiograph was 70 microGy. The measured scattered radiation range at a 2 m distance from the neonatal intensive care unit (NICU) was (11-17 microGy) per radiograph. Mean effective doses were 16 and 27 microSv per procedure for the chest and abdomen, respectively. ESD(TLD) was well correlated with ESD(TO) obtained from the total chest and abdomen radiographs for each infant (R(2) = 0.86). The radiation risks for childhood cancer estimated from the effective dose were 0.4 x 10(-6) to 2 x 10(-6) and 0.6 x 10(-6) to 2.9 x 10(-6) for chest and abdomen radiographs, respectively. CONCLUSION: The results of our study show that neonates received acceptable doses from common radiological examinations. Although the contribution of scatter radiation to the neonatal dose is low, considering the sensitivity of the neonates to radiation, further protective action was performed by increasing the distance of the infants from each other. 相似文献
19.
Purpose
We studied the effect of varicocele ligation on Kruger strict morphology criteria and semen parameters in patients with infertility.Materials and Methods
A total of 90 patients diagnosed with varicoceles and a normal morphological sperm ratio of less than 14% were evaluated before and 6 months after varicocelectomy. Preoperatively and postoperatively sperm density, motility and morphology using Kruger strict criteria were analyzed. The Wilcoxon test was used to measure levels of statistical significance in all analyses.Results
Significant improvement in sperm concentration and motility was evident after varicocele ligation (p <0.0002 and <0.0001, respectively). Using the Kruger classification sperm morphology evaluation revealed a significant increase in the percent of normal forms, and of forms with head and acrosome defects (p <0.0001, <0.0014 and <0.0028, respectively). There were no concomitant changes in strict morphology in forms with mid piece and tail defects or immature forms (p >0.05). Of the 90 patients 18 (20%) achieved a successful full-term pregnancy, including 14 via natural cycle intercourse and 4 by intrauterine insemination.Conclusions
Surgical correction of varicocele was associated with significant improvement in density, motility and sperm morphology evaluated using the Kruger classification. 相似文献20.
Ziya Cetinkaya Kazim Esen Ibrahim Hanefi Ozercan Bilal Ustundag Refik Ayten Erhan Aygen 《World journal of emergency surgery : WJES》2006,1(1):37