全文获取类型
收费全文 | 1075842篇 |
免费 | 71814篇 |
国内免费 | 1369篇 |
专业分类
耳鼻咽喉 | 15019篇 |
儿科学 | 34616篇 |
妇产科学 | 28625篇 |
基础医学 | 153489篇 |
口腔科学 | 29571篇 |
临床医学 | 94948篇 |
内科学 | 203814篇 |
皮肤病学 | 24454篇 |
神经病学 | 81496篇 |
特种医学 | 42970篇 |
外国民族医学 | 201篇 |
外科学 | 163338篇 |
综合类 | 21706篇 |
现状与发展 | 1篇 |
一般理论 | 263篇 |
预防医学 | 74884篇 |
眼科学 | 24535篇 |
药学 | 86151篇 |
7篇 | |
中国医学 | 2808篇 |
肿瘤学 | 66129篇 |
出版年
2019年 | 7765篇 |
2018年 | 11314篇 |
2017年 | 8929篇 |
2016年 | 10112篇 |
2015年 | 11279篇 |
2014年 | 15300篇 |
2013年 | 22237篇 |
2012年 | 30626篇 |
2011年 | 32350篇 |
2010年 | 18992篇 |
2009年 | 17851篇 |
2008年 | 30016篇 |
2007年 | 32137篇 |
2006年 | 32764篇 |
2005年 | 31092篇 |
2004年 | 29787篇 |
2003年 | 28603篇 |
2002年 | 27582篇 |
2001年 | 60056篇 |
2000年 | 61509篇 |
1999年 | 50945篇 |
1998年 | 12455篇 |
1997年 | 11005篇 |
1996年 | 11025篇 |
1995年 | 10335篇 |
1994年 | 9351篇 |
1993年 | 8864篇 |
1992年 | 37801篇 |
1991年 | 36284篇 |
1990年 | 35762篇 |
1989年 | 34297篇 |
1988年 | 30872篇 |
1987年 | 29988篇 |
1986年 | 28218篇 |
1985年 | 26456篇 |
1984年 | 19191篇 |
1983年 | 16118篇 |
1982年 | 8826篇 |
1979年 | 17034篇 |
1978年 | 11405篇 |
1977年 | 10232篇 |
1976年 | 8839篇 |
1975年 | 10068篇 |
1974年 | 11652篇 |
1973年 | 11273篇 |
1972年 | 10757篇 |
1971年 | 10092篇 |
1970年 | 9252篇 |
1969年 | 8940篇 |
1968年 | 7917篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
951.
Wing‐Hong Li Moon‐Tong Cheung Candace N.S. Ho Ting‐Pong Fung Kai‐Ming Ko Kelvin K.W. Yau 《Surgical Practice》2007,11(4):138-143
Aim: To examine the survival benefit of liver and lung resection for colorectal metastasis and the potential prognostic factors that affect patient survival. Methods: All patients who had resection of lung or liver metastasis for colorectal metastasis in Queen Elizabeth Hospital, Hong Kong from 1995 to 2004 were retrospectively reviewed. The overall and disease‐free survival was analysed, in particularly between liver and lung metastasis. All factors that may have affected the survival were entered into Cox's proportional hazards regression model to identify significant variables associated with survival. Results: At 5 years, the overall survival of patients who had resection of lung and liver metastasis was 44% and 38%, respectively; the disease‐free survival was 26% and 24%, respectively. Overall and disease‐free survival of patients with resection of lung metastasis was comparable to those with resection of liver metastasis. The differentiations of primary tumour and time to metastasis were shown to be significant prognostic factors influencing overall survival. Those patients with systemic chemotherapy after resection of colorectal metastasis demonstrated a significantly higher probability of overall survival. Conclusion: Resection of lung and liver metastases from colorectal origin was safe and both procedures improved survival. The use of chemotherapy after resection of metastasis significantly improved the overall survival. 相似文献
952.
953.
954.
955.
956.
957.
J Heckenkamp K Lieder E Lang M Aleksic M S Bendel M Gawenda J W U Fries J S Brunkwall 《European journal of vascular and endovascular surgery》2005,29(5):463-469
OBJECTIVES: The aim of this study was to investigate if radiation therapy (RT) favorably modulates wound healing at vein graft anastomoses. MATERIALS AND METHODS: Jugular vein grafts were sewn into carotid arteries in 32 rats which were randomly divided into two groups: RT (gamma source, 14 Gray, n=16) and control (C, sham irradiation, n=16). Grafts and adjacent arteries were analyzed at 2 (n=8) and 8 weeks (n=8) by histology, immunohistochemistry, and morphometry. RESULTS: Although, RT did not reduce the overall occurrence of intimal hyperplasia, the distribution differed. RT led to a reduction of intimal hyperplasia in arterial segments (median: C: 41.873 microm2; RT: 6.452 microm2, p < 0.0007). In contrast, RT augmented intimal hyperplasia in vein grafts (median: C: 30.287 microm2; RT: 90.455 microm2, p < 0.014). Vein graft diameters after RT were enlarged (median: C: 2.098 microm; RT: 3.381, p < 0.031). Over 80% of the cells were of mesenchymal origin in both groups. CONCLUSIONS: RT reduced intimal hyperplasia in arterial segments. However, RT led to graft dilatation and increased intimal hyperplasia in vein grafts. RT did not favorably modulate the vascular wound healing response in this model. 相似文献
958.
Edwin H. Preston He Xu Kiran K. Dhanireddy Jonathan P. Pearl Frank V. Leopardi Matthew F. Starost Douglas A. Hale Allan D. Kirk 《American journal of transplantation》2005,5(5):1032-1041
CD154-specific antibody therapy prevents allograft rejection in many experimental transplant models. However, initial clinical transplant trials with anti-CD154 have been disappointing suggesting the need for as of yet undetermined adjuvant therapy. In rodents, donor antigen (e.g., a donor blood transfusion), or mTOR inhibition (e.g., sirolimus), enhances anti-CD154's efficacy. We performed renal transplants in major histocompatibility complex-(MHC) mismatched rhesus monkeys and treated recipients with combinations of the CD154-specific antibody IDEC-131, and/or sirolimus, and/or a pre-transplant donor-specific transfusion (DST). Therapy was withdrawn after 3 months. Triple therapy prevented rejection during therapy in all animals and led to operational tolerance in three of five animals including donor-specific skin graft acceptance in the two animals tested. IDEC-131, sirolimus and DST are highly effective in preventing renal allograft rejection in primates. This apparently clinically applicable regimen is promising for human renal transplant trials. 相似文献
959.
960.
Dr. S. Besier T.M. Bingold F. Walcher K. Engels B. Spellerberg V. Brade C. Brandt 《Der Chirurg》2007,78(12):1148-1151
Streptococcus agalactiae, known as a pathogen that causes meningitis and septicemia in neonates, emerges as an invasive organism in nonpregnant adults. This case report describes the fulminant course of a necrotizing fasciitis (NF) with streptococcal toxic shock-like syndrome (STSS) in a 76-year-old diabetic patient caused by S. agalactiae, serotype V. Chronic diseases and immunodeficiency are considered to be risk factors for the acquisition of group B streptococcal disease. Since early surgical treatment in conjunction with antimicrobial and intensive care therapy is critical for the outcome of patients with NF and/or STSS, clinicians should be aware of invasive S. agalactiae infections in adults with subcutaneous emphysema. 相似文献