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31.
Tatsuo?KandaEmail author Tsutomu?Suzuki Shin-ichi?Kosugi Masato?Nakano Takashi?Ishikawa Satoru?Nakagawa Katsuyoshi?Hatakeyama 《Esophagus》2004,1(3):131-134
We present a case of esophageal carcinoma in which esophagectomy was not possible because of tuberculous fibrosing mediastinitis. A 77-year-old man was diagnosed with carcinoma of the thoracic esophagus and admitted to our hospital. Chest radiography on admission revealed no abnormality except pleural thickening of the pulmonary apices, suggesting a history of subclinical infection of tuberculous pleurisy. The patient underwent surgery with a curative intent. Thoracotomy revealed that the mediastinum had been replaced with dense fibrous tissues and was widely encased with laminar calcification. Esophagectomy was not performed because it was considered impossible to do so safely. Although diagnosis of fibrous mediastinitis was not made preoperatively, review of the preoperative computed tomographic scans revealed proliferation of mediastinal soft tissues that were associated with patchy and laminar calcifications. Tuberculous fibrosing mediastinitis is an uncommon but clinically important disease for physicians who are involved in the diagnosis and treatment of esophageal cancer. 相似文献
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Shirou Kuwabara Tadashi Nishimaki Yoichi Ajioka Shintarou Komukai Tsutomu Suzuki Hidenobu Watanabe Katsuyoshi Hatakeyama 《Digestive diseases and sciences》1998,43(8):1675-1677
It is well known that squamous carcinomasfrequently develop multifocally, either synchronously ormetachronously, in the upper aerodigestive tract (1).Such phenomena were first reported by Slaughter et al in 1953, and they were named fieldcancerization (2). Using recent molecular biologytechniques, these multiple carcinomas have been revealedto arise from independent origins (3). Esophagealcarcinomas have been reported to frequently metastasize tothe lymph nodes even at the early stage of tumorextension (4). Furthermore, simultaneous multifocalcancer development is not rare in the esophagus (5). In cases of intraesophageal multiple carcinomaswith lymph node metastases, the primary focus of themetastatic tumors cannot be identified by conventionalhistologic examination. Here we report a case of intraesophageal multiple carcinomas in whichthe attributed foci of lymph nodal metastases could beclearly identified by analyzing the p53 gene mutationalstatus used as a clonal marker. 相似文献
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Noninvasive investigation of exocrine pancreatic function: Feasibility of cine dynamic MRCP with a spatially selective inversion‐recovery pulse 下载免费PDF全文
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Uetsuka Y Hosoda S Kasanuki H Aosaki M Murasaki K Ooki K Inoue M Akiyama E Kitada M 《Heart and vessels》2000,15(3):124-128
The thrombotest (TT) technique has been widely used in Japan for monitoring oral anticoagulant therapy (OAT). The therapeutic
range was originally recommended to be 10%–25%. However, the International Committee for Standardization in Hematology/International
Committee on Thrombosis and Hemostasis (ICSH/ICTH) recommended using the international normalized ratio of prothrombin time
(PT-INR) for monitoring OAT. It is necessary to use a universal standard measure for monitoring OAT in accordance with the
ICSH/ISTH recommendation. We simultaneously measured TT and PT in blood samples from 1 157 patients on long-term warfarin
therapy, and studied the correlation between TT and PT-INR. An excellent linear correlation was obtained between TT-INR and
PT-INR with the regression equation PT-INR = 1.0420 TT-INR − 0.0987 (r = 0.905, P < 0.001). We also examined the correlation between the incidence of thromboembolism in 170 patients receiving warfarin therapy
after prosthetic valve replacement; 50.5% received concomitant antiplatelet therapy. Thromboembolism occurred in 9 of 170
patients during a mean follow-up period of 2.44 years. The average TT values in patients with and without thromboembolism
were 26.4% (PT-INR: 1.53) and 21.1% (1.73), respectively (P < 0.01). The incidence of thromboembolism did not differ significantly between patients on warfarin alone (average TT: 22.2%)
and those on warfarin and antiplatelet agent (average TT: 20.9%). Our results suggest that the incidence of thromboembolism
is low in Japan despite a less intensive regimen having been adopted.
Received: June 22, 2000 / Accepted: October 4, 2000 相似文献
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Katsuyoshi Sakaguchi Sawako Uehara Takakazu Yagi Shouichi Miyawaki 《Orthodontic Waves》2012,71(3):79-84
PurposeIt is clinically believed that humans with a broad and rounded dental arch accompanied by a shallow curve of Spee have good masticatory function. However, the relationship between them has not been elucidated fully. The purpose of this study was to quantitatively examine the relationship between occlusal curvatures and bite force.Materials and methodsBite force was measured and analyzed in 20 young adults with healthy permanent dentition and normal stomatognathic function using a bite force recording system. Study models of the mandibular dental arch were scanned with CCD cameras, and X, Y and Z coordinates of the cusp tips of the molars were recorded. Their occlusal curvatures were analyzed using a three-dimensional measurement system.ResultsBite force showed significant positive correlations (0.52 < R < 0.57) with the radius of the anteroposterior occlusal arc of the molar region and the radii of the translateral occlusal arcs in the second premolar, first molar and second molar regions, and showed significant positive correlation (R = 0.71) with the radius of the occlusal sphere of the molar region.ConclusionsIt was suggested that occlusal curvatures is related with the magnitude of bite force, and that the three dimensional spherical analysis of occlusal curvatures is useful predictor of the masticatory function. 相似文献