全文获取类型
收费全文 | 16043篇 |
免费 | 1030篇 |
国内免费 | 280篇 |
专业分类
耳鼻咽喉 | 234篇 |
儿科学 | 226篇 |
妇产科学 | 283篇 |
基础医学 | 2101篇 |
口腔科学 | 427篇 |
临床医学 | 1267篇 |
内科学 | 3718篇 |
皮肤病学 | 205篇 |
神经病学 | 1169篇 |
特种医学 | 664篇 |
外国民族医学 | 2篇 |
外科学 | 2499篇 |
综合类 | 590篇 |
现状与发展 | 2篇 |
一般理论 | 1篇 |
预防医学 | 888篇 |
眼科学 | 182篇 |
药学 | 1243篇 |
1篇 | |
中国医学 | 238篇 |
肿瘤学 | 1413篇 |
出版年
2023年 | 109篇 |
2022年 | 244篇 |
2021年 | 317篇 |
2020年 | 219篇 |
2019年 | 238篇 |
2018年 | 292篇 |
2017年 | 253篇 |
2016年 | 266篇 |
2015年 | 293篇 |
2014年 | 469篇 |
2013年 | 485篇 |
2012年 | 841篇 |
2011年 | 915篇 |
2010年 | 542篇 |
2009年 | 512篇 |
2008年 | 770篇 |
2007年 | 801篇 |
2006年 | 753篇 |
2005年 | 730篇 |
2004年 | 697篇 |
2003年 | 624篇 |
2002年 | 665篇 |
2001年 | 547篇 |
2000年 | 589篇 |
1999年 | 504篇 |
1998年 | 184篇 |
1997年 | 142篇 |
1996年 | 140篇 |
1995年 | 112篇 |
1994年 | 107篇 |
1993年 | 112篇 |
1992年 | 377篇 |
1991年 | 320篇 |
1990年 | 338篇 |
1989年 | 324篇 |
1988年 | 286篇 |
1987年 | 288篇 |
1986年 | 248篇 |
1985年 | 245篇 |
1984年 | 175篇 |
1983年 | 138篇 |
1982年 | 68篇 |
1981年 | 65篇 |
1979年 | 107篇 |
1978年 | 85篇 |
1977年 | 90篇 |
1975年 | 68篇 |
1974年 | 78篇 |
1972年 | 68篇 |
1968年 | 65篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
11.
12.
13.
Yukinori Sakao Toru Sakuragi Yuji Takeda Masafumi Natsuaki Tsuyoshi Itoh 《General thoracic and cardiovascular surgery》2003,51(10):537-540
We experienced a rare case of giant cell tumor (GCT) arising in the 5th rib involving the 5th vertebral body and transverse process. A 57-year-old man presented with a well-defined mass in the left thoracic cavity on chest x ray examination. Chest computed tomography showed a heterogeneous 7cm-diameter mass originating in the posterior segment of the left 5th rib. The tumor had spread to the 5th thoracic vertebra destroying the left half of the body and transverse process. Magnetic resonance imaging showed a heterogeneous-intensity mass involving the 4th to 6th ribs. A radical excision of the tumor followed by a 50 Gy radiotherapy was performed after embolization of the feeding arteries. The pathological diagnosis was a GCT. The patient remains well without evidence of recurrence for 6 years following surgery. The present case is only the 14th case of GCT arising in the rib to have been reported in Japan. 相似文献
14.
M Oishi H Yokoyama N Abe K Iwasaki F Okuguchi K Kawai H Sugimoto H Takamura H Takeda K Doi K Hirao S Ikeda 《Diabetic medicine》2007,24(10):1149-1155
AIMS: To study the time and cost involved in the care of newly registered outpatients with Type 2 diabetes mellitus (DM), compared with patients with hypertension and/or hyperlipidaemia (HTL). METHODS: A total of 313 patients with DM and 58 patients with HTL without diabetes were registered on their first visits to 11 diabetes clinics across Japan. The time and cost involved in their care was recorded over the following 5 months. RESULTS: In the first 3 months, there was an extensive time commitment to both groups. The time spent by physicians was 1.5 times longer for DM than for HTL. The total care time spent by all the care providers for DM was twice that for HTL. The cost of DM care was twice that for HTL, with the cost of medicines excluded. However, half of the cost for DM was for laboratory tests. When these were excluded, and the remaining cost divided by the time spent, the amount for DM was half of that for HTL. Over the 5 months, mean glycated haemoglobin (HbA(1c)) in DM patients improved from 8.0% to 6.5%, and 72% of DM patients achieved the glycaemic target of HbA(1c) < or = 6.5%. CONCLUSIONS: DM care in a diabetes clinic requires a great deal more time and resources than HTL to achieve the best outcome. An educational system for self care, presently lacking in the primary care setting in Japan, would improve glycaemic control for DM patients in the community. 相似文献
15.
Koichiro Ueki Yukari Hashiba Kohei Marukawa Kan Yoshida Chika Shimizu Kiyomasa Nakagawa Etsuhide Yamamoto 《Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics》2007,104(1):38-43
OBJECTIVE: To compare postoperative maxillary stability following Le Fort I osteotomy for the correction of occlusal cant as compared with conventional Le Fort I osteotomy for maxillary advancement. STUDY DESIGN: The subjects were 40 Japanese adults with jaw deformities. Of these, 20 underwent a Le Fort I osteotomy and intraoral vertical ramus osteotomy (IVRO) to correct asymmetric skeletal morphology and inclined occlusal cant. The other 20 patients underwent a Le Fort I osteotomy and sagittal split ramus osteotomy (SSRO) to advance the maxilla. Lateral and posteroanterior cephalograms were taken postoperatively and assessed statistically. Thereafter, the 2 groups were followed for time-course changes. RESULTS: There was no significant difference between the 2 groups with regard to time-course changes during the immediate postoperative period. CONCLUSION: This suggests that maxillary stability after Le Fort I osteotomy for cant correction does not differ from that after Le Fort I osteotomy for maxillary advancement. 相似文献
16.
Yuji Takeda Naoki Minato Yuji Katayama Tomoki Shimokawa 《General thoracic and cardiovascular surgery》2005,53(1):42-45
Two successful cases of the surgical treatment for coronary artery aneurysm (non-Kawasaki disease) were reported. The first
case had a saccular aneurysm on the left circumflex coronary artery (LCx) #14. Resection of the LCx aneurysm was performed
subsequent to single vessel coronary artery bypass grafting (CABG) to the distal portion of LCx#14 under the cardioplegic
cardiac arrest. The second case had aneurysms on both the left anterior descending artery (LAD) #7 (fusiform) and the LCx#11
(saccular). After double vessel CABG to LAD#7 and LCx#11, ligation or resection of two aneurysms was performed successfully.
Postoperative courses have been uneventful with good angiographic results achieved. Since these surgical procedures demonstrated
safety, the patients are expected to achieve a good long-term prognosis. 相似文献
17.
The kinetics and dynamics of glial fibrillary acidic protein (GFAP) assembly was explored by a fluorescence energy transfer assay method. Purified GFAP was stoichiometrically labeled at a single cysteine residue with fluorescein-maleimide. Soluble labeled GFAP in a low ionic strength buffer was assembled into 10 nm filaments by rapidly increasing the ionic strength, and the kinetics of GFAP assembly was monitored by the reduction in fluorescence due to self-quenching of fluorescein. The extent of fluorescence quench correlated with both the formation of 10 nm filament morphology and the amount of protein pelleted at 12,000g. The assembly of GFAP is critically dependent upon both protein and magnesium ion concentration, and at the critical concentration for GFAP assembly is approximately 40 micrograms/ml. Disassembly of GFAP filaments was also observed as a relief of fluorescence quenching after dilution of labeled GFAP filaments. When labeled GFAP filaments were mixed with an excess of unlabeled filaments, a rapid increase of fluorescence was observed, which is due to an exchange of subunits between labeled and unlabeled GFAP filaments. These results indicate that GFAP filaments are dynamic structures and that a small pool of kinetically active unassembled GFAP subunits are in a dynamic equilibrium with assembled GFAP filaments. The ability of GFAP to assemble, disassemble, and undergo subunit exchange has important implications for the organization and dynamics of astroglia cell cytoskeleton during development and in response to injury. 相似文献
18.
Tsuyoshi Takeda Hiroyuki Ishida Yukio Horiuchi Yasushi Nakao Yutaka Yabe 《Journal of orthopaedic science》1997,2(6):372-377
We examined radiographs of the elbows of the pitching arms of 79 professional baseball pitchers (mean age, 25.1 years; mean
duration of professional career, 4.7 years) and noted the frequency and size of spurs, bone fragments, and intra-articular
loose bodies according to site. The influence of duration of professional baseball career on these osteoarthritic changes
was also investigated. The olecranon tip was the most frequent site of spurs (62/79; 78.5%), and fragmentation of the spur
was detected in 17 joints. The frequency of spurs was also high at the medial margin of the olecranon, the tip of the coronoid
process, the medial margin of the sigmoid notch, the medial margin of the trochlea and the olecranon fossa. In 38 subjects,
spurs were observed at the distal portion of the radial notch of the ulna. However, few pitchers had osteoarthritic changes
in the humeral capitellum or radial head. Intra-articular loose bodies were detected in 4 of 79 joints (5.1%), and bone fragments
were present below the medial humeral epicondyle in 25 of 79 joints (31.6%). Osteoarthritic changes in the elbow joint appeared
to be attributable mainly to traction stress and impingement associated with extension and valgus strain. Significant osteoarthritic
changes were often found in professional pitchers whose careers exceeded 5 years. 相似文献
19.
本文根据Svennerholm和蒋谷人等的方法略加改良,测定了蚌埠地区113例正常人,71例恶性肿瘤患者和82例非肿瘤疾病患者血清脂质结合唾液酸(LSA)的含量。正常值为12.4mg/dl(SD=±3.6mg/dl),71例不同肿瘤患者的平均值为28.2mg/dl(SD=±9.7mg/dl),阳性率为88.7%,82例非肿瘤疾病患者的平均值为16.82mg/dl(SD=±5.4mg/dl),假阳性率为17%。方法的灵敏度,重复性(平均CV=3.6%)和回收率(平均回收率=101.4%)测定结果是满意的。本研究的初步结果表明,血清LSA测定对肺癌、白血病、胃癌和食管癌具有一定的临床诊断价值。 相似文献
20.