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91.
Murat Akin Sezai Leventoglu B. Bulent Mentes Hasan Bostanci Hakan Gokbayir Kadir Kilic Ersin Ozdemir Zafer Ferahkose 《Surgery today》2010,40(8):757-762
Purpose
Pilonidal sinus disease (PSD) is usually seen on the sacrococcygeal region in adolescent patients. The current study analyzed the outcome of the rhomboid excision and the Limberg flap procedure (cLF) in comparison to the modified Limberg flap procedure (mlF) for PSD. 相似文献92.
Luby SP Kadir MA Yushuf Sharker MA Yeasmin F Unicomb L Sirajul Islam M 《Tropical medicine & international health : TM & IH》2010,15(12):1508-1516
Objectives To pilot two intensive hand hygiene promotion interventions, one using soap and one using a waterless hand sanitizer, in low‐income housing compounds in Dhaka, Bangladesh and assess subsequent changes in handwashing behaviour and hand microbiology. Methods Fieldworkers randomized 30 housing compounds: 10 received handwashing promotion with free soap, 10 received handwashing promotion with free waterless hand sanitizer and 10 were non‐intervention controls. Fieldworkers assessed handwashing behaviour by structured observation and collected hand rinse specimens. Results At baseline, compound residents washed their hands with soap 26% of the time after defecation and 30% after cleaning a child’s anus but <1% at other times. Compared with baseline, residents of soap intervention compounds were much more likely to wash their hands with soap after faecal contact (85–91%), before preparing food (26%) and before eating (26%). Compounds that received waterless hand sanitizer cleansed their hands more commonly than control compounds that used soap (10.4%vs. 2.3%), but less commonly than soap intervention compounds used soap (25%). Post‐intervention hand rinse samples from soap and sanitizer compounds had lower concentrations of faecal indicator bacteria compared with baseline and control compounds. Conclusions Waterless hand sanitizer was readily adopted by this low‐income community and reduced hand contamination but did not improve the frequency of handwashing compared with soap. Future deployments of waterless hand sanitizers may improve hand hygiene more effectively by targeting settings where soap and water is unavailable. 相似文献
93.
Kadir Yildirim Saliha Karatay Ramazan Cetinkaya Hulya Uzkeser Akın Erdal Ilyas Capoglu Fazile Hatipoglu Erdem 《Rheumatology international》2010,30(3):305-308
This study was carried out to determine lumbar and femoral bone mineral density (BMD) in patients with familial Mediterranean
fever (FMF), an autosomal-recessive disease characterized by recurrent episodes of peritonitis, pleuritis, and arthritis,
which are usually associated with fever. In patients with FMF and control subjects, erythrocyte sedimentation rate (ESR) and
C-reactive protein (CRP) were measured. BMD was determined at the lumbar spine (L1–4) and the femoral regions (neck and total)
using dual energy X-ray absorptiometry. Twenty-eight FMF patients and 30 control subjects without a history of inflammatory
disease participated in our study. The demographic variables, such as age, sex and body mass index were similar between patients
and controls (P > 0.05). We found statistically significant difference in ESR and CRP between FMF patients and controls (P < 0.01, P < 0.05 respectively). There was statistically significant difference in lumbar spine, femoral neck, and total femur BMD between
FMF patients and control groups (P < 0.001, P < 0.01, P < 0.01 respectively).Our study indicates that lumbar spine and femoral neck and total femur BMD in patients with FMF may
be lower than in healthy subjects. 相似文献
94.
Aylin Üstündağ Kemal Şimşek Hakan Ay Kadir Dündar Sinan Süzen Ahmet Aydın Yalçın Duydu 《Toxicology in vitro》2012,26(7):1209-1215
Hyperbaric oxygen (HBO) therapy is successfully applied for a wide variety of diseases. However, recent studies in humans undergoing (HBO) therapy have revealed that HBO is able to induce oxidative DNA damage especially in lymphocytes while the biological significance of this outcome is still not clear. HBO mediated DNA damage in lymphocytes has been determined by using the alkaline version of the comet assay in order to detect DNA strand breakages in patients undergoing HBO therapy. Blood samples were obtained from 100 voluntary patients and were drawn by venipuncture before and immediately after the first session of HBO treatment. The DNA damaging effect of HBO has also been evaluated in the fifth session of HBO therapy. DNA strand breakages were significantly increased after the first session of HBO treatment. However the elevated DNA strand breaks returned to their normal levels in lymphocytes after two hours of in vitro incubation. The elevated DNA strand breaks consistently decreased and reached to the baseline levels after the fifth session of HBO therapy. The results of this study, conducted in patients undergoing HBO therapy, support the existence of the previously reported cellular adaptive response against HBO mediated oxidative DNA damage in experimental studies. 相似文献
95.
BACKGROUND: Hemangioma is one of the most common benign tumors of the spine, and it remains silent in the vast majority of subjects afflicted. Pregnancy is a known risk factor for symptomatic conversion of the previously silent vertebral hemangiomas. However, the occurrence is rare with only 26 cases reported in the English medical literature. CASE DESCRIPTION: A 22-year-old woman in her 36th week of gestation presented with acute onset of upper back pain and progressive paraplegia. Imaging studies revealed a T4 vertebral hemangioma, which involved the vertebral body, pedincules, transverse, and spinous process with a focal extradural extension of soft tissue component. She underwent emergent cesarean delivery and endovascular embolization, respectively. Her symptoms and neurologic deficits improved quickly. Her complaints restarted 2 years after embolization. Surgical treatment which consists of intraoperative vertebraplasty and segmental fixation was performed. The patient's postoperative recovery was excellent. CONCLUSION: According to literature review and our patient's outcome, pregnancy may induce neurologic symptoms and signs in silent spinal hemangiomas. The way of management is decided by whether the neurologic deficits depend on the deformity caused by hemangioma or some other factors including vascular insufficiency. 相似文献
96.
Köseoğlu B Yilmaz E Ceylan K Uzun E Bayram I Hizli F 《International urology and nephrology》2009,41(1):85-91
Introduction The aim of the present study was to evaluate the effects of erythropoietin (EPO) on the histopathology of testes after unilateral
testicular torsion and detorsion.
Materials and methods Twenty-five male Sprague–Dawley rats weighing 120 g were used in this study. The rats were randomly divided into three groups,
a sham group consisting of five rats and the other two groups consisting of ten rats. In group 1 (sham group), right orchiectomy
with no additional intervention was performed. In group 2 (T/D group), torsion was created by rotating the testis 720° in
a clockwise direction for 4 h. After a 4-h torsion period, the right testis was detorted and replaced into the scrotum for
4 h. After the torsion, 0.5 cc 0.9% NaCl solution was injected once and three times in a week (total 12 doses). In group 3
(T/D + erythropoietin; EPO group), the same surgical procedure was done as in group 1, but EPO 1,000 IU/kg was injected just
before the detorsion and three times in a week. At the end of each procedure, bilateral orchiectomies were performed for the
histopathological examinations in all groups.
Results We examined the testes weight, vascularization of the region between the seminiferous tubules, percentage of necrotic seminipherous
tubules, and maturation of spermatogenesis in terms of necrosis, sertoli cells, maturation arrest of spermatogenesis, hypospermatogenesis,
and normal spermatogenesis of torsioned testis tissues with and without EPO treatment. Extremely significant differences in
testicular weight were observed in group 1 compared to groups 2 and 3 (P < 0.001).
Conclusion Administration of EPO significantly influenced the rescue of testicular function by preserving the intact seminiferous tubular
morphology, lowering the percentage of necrotic seminipherous tubules, and significantly reducing histological damage (P < 0.05). 相似文献
97.
98.
99.
Akyüz F Demir K Ozdil S Aksoy N Poturoğlu S Ibrişim D Kaymakoğlu S Beşişik F Boztaş G Cakaloğlu Y Mungan Z Cevikbaş U Okten A 《Digestive diseases and sciences》2007,52(9):2359-2367
Our aım was to evaluate effects of metformin, rosiglitazone, and diet with exercise in nonalcoholic fatty liver disease. Forty-seven
patients (mean age, 44±10 years; 17 female) whose ALT levels had been high for at least 6 months and with hepatosteatosis
detected by liver biopsy and/or USG were enrolled in this study. Of these, 12 were treated with 850 mg/day metformin (group
1), 11 with 4 mg/day rosiglitazone (group 2), and 24 with diet and exercise (group 3) for 1 year. ALT normalization at months
6 and 12 was accepted as treatment response. Liver biopsy was performed in all patients in groups 1 and 2 before treatment
and 12 patients (4 in group 1, 8 in group 2) after treatment; but in group 3 it was performed only in patients who approved
this procedure (12 patients). Body mass index did not change in groups 1 and 2, but it decreased significantly in group 3
(30±3 to 28±2 kg/m2) at month 12. Treatment response rate was 33.3, 54.5, and 54.2% in groups 1, 2, and 3, respectively, at month 6. This rate
was 22.2, 37.5, and 41.2 in groups 1, 2, and 3, respectively, at month 12. Rate of steatosis and stage of fibrosis did not
change after treatment. Diet with exercise seems to be superior to metformin and rosiglitazone. Decreasing treatment response
at month 12 compared to month 6 may be due to fluctuations of ALT levels. Treatment response should be evalulated histologically. 相似文献
100.
Symptomatic interhemispheric arachnoid cysts (ACs) are extremely rare lesions seen more frequently in the elderly. Only 13 cases of symptomatic interhemispheric ACs in the elderly have previously been reported. Herein, we describe a 70-year-old female with symptoms of vertigo, memory and behavior disturbances. Magnetic resonance imaging (MRI) revealed a giant arachnoid cyst (AC) on the interhemispheric fissure, which was exerting a mass effect and displacement on the corpus callosum and anterior cerebral vessels, with a massive midline shift. The patient was treated with a cysto-peritoneal shunt. Reports to date have reviewed the pathology, clinical presentation, radiology and surgical management of interhemispheric symptomatic arachnoid cysts in elderly patients. 相似文献