首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   1335818篇
  免费   94404篇
  国内免费   2908篇
耳鼻咽喉   19715篇
儿科学   40227篇
妇产科学   38659篇
基础医学   187209篇
口腔科学   39818篇
临床医学   112615篇
内科学   262462篇
皮肤病学   30205篇
神经病学   106358篇
特种医学   53665篇
外国民族医学   435篇
外科学   208219篇
综合类   31049篇
现状与发展   6篇
一般理论   436篇
预防医学   92033篇
眼科学   31358篇
药学   100053篇
  4篇
中国医学   2988篇
肿瘤学   75616篇
  2018年   11737篇
  2015年   11871篇
  2014年   16683篇
  2013年   25239篇
  2012年   32994篇
  2011年   34858篇
  2010年   20728篇
  2009年   20224篇
  2008年   33569篇
  2007年   36675篇
  2006年   37248篇
  2005年   36003篇
  2004年   35081篇
  2003年   34057篇
  2002年   33584篇
  2001年   63613篇
  2000年   65322篇
  1999年   55386篇
  1998年   14650篇
  1997年   13458篇
  1996年   12937篇
  1995年   12221篇
  1994年   11467篇
  1992年   42761篇
  1991年   41280篇
  1990年   40553篇
  1989年   39550篇
  1988年   36963篇
  1987年   36408篇
  1986年   34899篇
  1985年   33101篇
  1984年   24822篇
  1983年   21052篇
  1982年   12664篇
  1981年   11568篇
  1980年   10772篇
  1979年   23923篇
  1978年   17068篇
  1977年   14834篇
  1976年   13386篇
  1975年   15267篇
  1974年   18080篇
  1973年   17560篇
  1972年   16810篇
  1971年   15717篇
  1970年   14914篇
  1969年   14346篇
  1968年   13460篇
  1967年   12015篇
  1966年   11258篇
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
991.
This study has shown that the retinae of Prototherian (egg-laying) mammals possess two neuronal types that are present in non-mammalian retinae, but absent or morphologically different in the retinae of Eutherian (placental) mammals. First, endogenous serotonin-like immunoreactivity has been localized in a population of presumptive amacrine cells in the platypus retina, the first such report in a mammalian retina. Second, the protein kinase C-immunoreactive (PKC-IR) bipolar cells in the echidna retina appear similar to the PKC-IR bipolars in the chicken retina, in that their dendrites give rise to a Landolt's club and their axons are multistratified. By contrast, the PKC-IR rod bipolar cells in the rabbit and in the brushtail possum, a Metatherian (marsupial) mammal, have no Landolt's clubs and their axons form terminal lobes in the innermost stratum of the inner plexiform layer.  相似文献   
992.
The study examines whether the order of administering 2 doses of quinpirole (0.5 and 8 mg/kg) affects the development of behavioral sensitization, as measured by the amount of forward progression and mouthing. Results show that injection of the high dose greatly enhances the subsequent locomotor response to the low dose of quinpirole, but not vice versa. Mouthing activity is not influenced by order of administration but is significantly greater at the higher dose of quinpirole. The present findings are consistent with a hypothesis that locomotor sensitization involves down-regulation of a D1 tone normally inhibitory to D2 locomotor activation.  相似文献   
993.
The influence of beta-blockers in short- and long-term application on the epithelium of the cornea was studied in rabbits with intact tear film, concentrating not on the completeness of the drug group but on general differences. The new unpreserved beta-blocker timolol was compared on an exemplary level with the following beta-blocker formulas: (1) beta-blocker eye drops with 0.01% of the preservative benzalkonium chloride; (2) beta-blocker eye drops with 0.005% of the preservative benzalkonium chloride, and (3) beta-blocker eye drops with 0.004% of the preservative benzalkonium chloride and the tear substitute polyvinyl alcohol. Exposure time in the short-term test was 30 min, in long-term tests the time was 24 weeks. Any cell damages observed were of only minor importance and rarely of clinical relevance; however, it could be shown that micromorphological cell reactions differed as a function of the preservative concentration. Complete absence of preservatives causes no difference in micromorphologically relevant changes in comparison with the control group. Drugs without preservatives are thus a meaningful alternative for patients with allergies, sensitive eyes or existing impairment of the precorneal film.  相似文献   
994.
Efficacy of diltiazem in the treatment of diffuse oesophageal spasm   总被引:1,自引:1,他引:0  
Calcium antagonist relax smooth muscle, a possible useful concept in treatment of diffuse oesophageal spasm. Therefore the effects of oral diltiazem (60 mg t.d.s.) and placebo were compared in eight patients with diffuse oesophageal spasm in a 10-week double-blind crossover study. The patients recorded the severity of chest pain and/or dysphagia in daily pain diaries using visual analogue scales. Chest pain index and dysphagia index were calculated by multiplying frequency with daily intensity of each individual symptom. When compared to placebo, diltiazem did not significantly change the overall dysphagia index and chest pain index. An individual sizeable reduction of dysphagia was attained on diltiazem in four out of six patients and in six out of eight patients suffering from chestpain. Side effects were not seen during diltiazem therapy. Diltiazem, in our study, did not yield in a significant improvement of symptoms in diffuse oesophageal spasm. Diltiazem, however, can offer relief in selected individual patients suffering from diffuse oesophageal spasm.  相似文献   
995.
A series of 5-alkyl-5-phenylbarbituric acid analogues were shown to be potent hypolipidemic agents in rats and mice at 20 mg/kg/day. This dose is lower than that required for hypolipidemic activity for clofibrate and nicotinic acid derivatives in rodents and man. These new derivatives reduced both serum cholesterol and triglyceride levels in rodents by either the oral or intraperitoneal route of administration. Previous studies have demonstrated that similar heterocyclic compounds, i.e. cyclic imides, glutarimides and hydantoins are potent hypolipidemic agents in rodents. The barbituric acid derivatives probably interfered with de novo synthesis of cholesterol and fatty acids in the early steps since the agents inhibit the activities of ATP-dependent citrate lyase and acetyl-CoA synthetase. Triglyceride synthesis may be blocked since the agents inhibited the rate limiting enzyme, sn-glycerol-3-phosphate-acyl-transferase. Rat tissue lipids especially cholesterol and triglycerides were reduced after 14 days treatment. Fecal lipids were increased in cholesterol and phospholipid content by selected compounds. The rat serum lipoprotein after 14 days drug administration showed reduced VLDL-cholesterol and HDL-triglyceride contents. The modulation of the lipid content of the serum lipoproteins by the barbituric acids suggest that these agents may be helpful in treating clinical hyperlipidemic disease states.  相似文献   
996.
997.
Summary An anthropometric study was performed in 95 subjects (53 male, 42 female) with Parkinson's disease. Weight, height, triceps and biceps skin-fold thicknesses, and mid-arm circumference were recorded. A high incidence of undernutrition was found (23.6% of males and 22.5% of females, as defined by recent British guidelines). A subgroup of severely disabled patients with Parkinson's disease had a significantly lower mean body mass index than a similarly disabled control group with chronic pyramidal upper motor neuron lesions (males 20.6v 23.2 kg/m2 p<0.05; females 20.6v 26.6 kg/m2 p<0.01), suggesting that the undernutrition is not due to chronic illness or immobility alone. Correlation between anthropometric indices and clinical features of disease demonstrated that the presence of moderate or severe dyskinetic movements was the clinical parameter most strongly related to undernutrition. The reduction in anthropometric indices was most marked for skin fold thickness (related to percentage body fat) and least for arm muscle circumference (related to lean body mass); therefore the weight loss seen in Parkinson's disease is primarily due to fat loss rather than muscle loss.  相似文献   
998.
999.
First there is given a definition of occupation related diseases of the musculoskeletal system as a subject to the Swiss federal law of social insurance. As a relation to age and sex, the incidence, the following time of work incapacity and the financial consequences of disability are reported within a period from 1970 to 1983. Although the results are highly specific to Swiss legislation, the international comparison might be of interest.  相似文献   
1000.
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号