全文获取类型
收费全文 | 838篇 |
免费 | 29篇 |
国内免费 | 2篇 |
专业分类
耳鼻咽喉 | 17篇 |
儿科学 | 71篇 |
妇产科学 | 20篇 |
基础医学 | 68篇 |
口腔科学 | 84篇 |
临床医学 | 55篇 |
内科学 | 122篇 |
皮肤病学 | 11篇 |
神经病学 | 24篇 |
特种医学 | 40篇 |
外科学 | 225篇 |
综合类 | 11篇 |
一般理论 | 1篇 |
预防医学 | 17篇 |
眼科学 | 65篇 |
药学 | 20篇 |
肿瘤学 | 18篇 |
出版年
2024年 | 2篇 |
2023年 | 7篇 |
2022年 | 17篇 |
2021年 | 25篇 |
2020年 | 12篇 |
2019年 | 18篇 |
2018年 | 21篇 |
2017年 | 17篇 |
2016年 | 18篇 |
2015年 | 19篇 |
2014年 | 24篇 |
2013年 | 43篇 |
2012年 | 56篇 |
2011年 | 58篇 |
2010年 | 38篇 |
2009年 | 31篇 |
2008年 | 62篇 |
2007年 | 64篇 |
2006年 | 63篇 |
2005年 | 76篇 |
2004年 | 64篇 |
2003年 | 38篇 |
2002年 | 35篇 |
2001年 | 7篇 |
2000年 | 7篇 |
1999年 | 7篇 |
1998年 | 4篇 |
1997年 | 4篇 |
1996年 | 6篇 |
1995年 | 8篇 |
1994年 | 3篇 |
1993年 | 3篇 |
1992年 | 3篇 |
1991年 | 1篇 |
1990年 | 1篇 |
1987年 | 1篇 |
1986年 | 3篇 |
1985年 | 1篇 |
1971年 | 1篇 |
1940年 | 1篇 |
排序方式: 共有869条查询结果,搜索用时 15 毫秒
31.
Faik Kose Zafer Turkyilmaz Kaan Sonmez Aylar Poyraz Ozlem Gulbahar 《Renal failure》2016,38(8):1283-1290
Background: In this study, it was aimed to determine the effects of alfuzosin on experimentally generated unilateral partial ureteropelvic junction obstruction (UPO) in rats.Materials and methods: Thirty Long–Evans rats were randomly allocated into five groups. In control group (C), nothing was performed; in group Sham (S) only laparotomy was done; in Alfuzosin group (A) only alfuzosin was administered for two weeks (10?mg/kg/day p.o.) without any surgery; in UPO group, unilateral UP junction obstruction was produced; and in the Group UPT (ureteropelvic obstruction?+?treatment), alfuzosin was administered for two weeks (10?mg/kg/day p.o.) in addition to UPO production. Renal pelvic anteroposterior diameters were determined with ultrasonography (USG) and renal arterial resistivity indexes by color Doppler USG. Urine was collected both at the beginning and at the end of the experiment for 24?h in all the groups and at the end of the experiment, blood samples were obtained. Blood and urine electrolytes and TGF-β1, urine density, urine β2 microglobulin levels were determined. Renal tissue samples harvested from all of the rats were histopathologically evaluated. Results were determined using one-way ANOVA t-test; p?<?0.05 was accepted as significant.Results: Urine density in the UPT group was lower with respect to UPO group and blood electrolytes were preserved as close to normal (p?<?0.05). In the UPT group, urine TGF-β1 and blood TGF-β1, blood β2 microglobulin levels and histopathologic damage scores were lower compared to the UPO group (p?<?0.05).Conclusion: It is shown in this experimental unilateral partial UPO model that alfuzosin treatment prevents obstructive renal damage. 相似文献
32.
33.
34.
Soldozy Sauson Yağmurlu Kaan Kumar Jeyan Elarjani Turki Burks Josh Jamshidi Aria Luther Evan Liu Kenneth C. Benjamin Carolina G. Starke Robert M. Park Min S. Syed Hasan R. Shaffrey Mark E. Komotar Ricardo J. 《Neurosurgical review》2022,45(2):1255-1261
Neurosurgical Review - As the aging population continues to grow, so will the incidence of age-related conditions, including idiopathic normal pressure hydrocephalus (iNPH). The pathogenesis of... 相似文献
35.
36.
Adherence,persistence, and treatment discontinuation with sitagliptin compared with sulfonylureas as add‐ons to metformin: A retrospective cohort database study 下载免费PDF全文
37.
Merih Onal Bahar Colpan Cagdas Elsurer Mete Kaan Bozkurt Alparslan Turan 《Acta oto-laryngologica》2020,140(7):583-588
AbstractBackground: Tongue-related complications can be seen in suspension laryngoscopy (SL) procedures.Aims/objectives: This study aimed to detect tongue edema associated with the pressure exerted by a rigid direct laryngoscope by measuring the tongue area using ultrasonography (USG) in patients undergoing SL procedures.Material and methods: The study group included 31 patients and the control group consisted of 33 patients. Submental USG examinations of the tongue in the coronal plane were performed. In the study and control groups, the first examination (TA1) was done immediately after intubation and the second examination (TA2) was done after the surgery procedure but before extubation. The USG results regarding tongue area for both the groups were compared.Results: The study and control groups significantly differed in terms of the postoperative tongue area measurements (TA2), as well as tongue edema (based on the TA2???TA1) values.Conclusions and significance: Direct rigid laryngoscopes may cause tongue edema in SL procedures which was demonstrated by the USG. This tongue edema can be a result of ischemia–reperfusion injury in the tongue due to the pressure exerted by a direct rigid laryngoscope. This study is the first to demonstrate the possible role of USG examination in determining the side effects of SL procedures on the tongue. Trial Registration ClinicalTrials.gov Identifier: NCT04205253 相似文献
38.
39.
F. Namavar J. A. Kaan A. M. J. J. Verweij-van Vught W. A. C. Vel M. Bal A. D. M. Kester D. M. MacLaren 《European journal of clinical microbiology & infectious diseases》1986,5(3):324-329
Bactericidal action of human polymorphonuclear leucocytes on
Escherichia coli
in the presence of
Bacteroides fragilis
grown in subinhibitory concentrations of clindamycin, metronidazole and fusidic acid was studied.Bacteroides fragilis
grown in the absence of drugs significantly inhibited the killing of
Escherichia coli.Bacteroides fragilis grown in the presence of the drugs had a reduced inhibitory effect on the killing of
Escherichia coli
but this reduction was only significant for
Bacteroides fragilis
grown in 1/2 MIC of clindamycin. The phagocytosis of
Bacteroides fragilis
grown with and without clindamycin, as measured by killing, was the same. Complement consumption of
Bacteroides fragilis
grown with and without clindamycin did not differ. Clindamycin-treated
Bacteroides fragilis
fixed C3 to a significantly lower degree than did untreated bacteria. The chemiluminescence of
Escherichia coli
opsonized with serum preincubated with clindamycin-treated
Bacteroides fragilis
was significantly higher than with serum preincubated with untreated bacteria. These results suggested that in killing experiments of mixed
Escherichia coli
and
Bacteroides fragilis,the mechanism underlying the reduced inhibitory capacity of clindamycin-exposed
Bacteroides fragilis
is related to greater availability of C3 in serum for opsonization of
Escherichia coli. 相似文献
40.
Alper Ucak M.D. Burak Onan M.D. Bilal Kaan Inan M.D. Veysel Temizkan M.D. Murat Ugur M.D. Ahmet Turan Yilmaz M.D. 《Journal of cardiac surgery》2010,25(3):336-339
Abstract Hybrid repair of an acute type B aortic dissection with endovascular stenting and aortic arch debranching is an acceptable treatment in complicated type B dissection. We present the case of a 71‐year‐old man presenting with acute type B aortic dissection and concomitant aneurysm of the distal aortic arch, who underwent an uneventful hybrid procedure, which involved subclavian‐to‐subclavian bypass before endovascular stent‐graft placement to the aortic arch. (J Card Surg 2010;25:336‐339) 相似文献