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ANEES THAJUDEEN M.D. WARREN M. JACKMAN M.D. BRIAN STEWART M.S. IVAN COKIC M.D. HIROSHI NAKAGAWA M.D. Ph.D. MICHAEL SHEHATA M.D. ALLEN M. AMORN M.D. AVINASH KALI M.S. EZH LIU M.D. DORON HARLEV M.Sc. NATHAN BENNETT M.Eng. ROHAN DHARMAKUMAR Ph.D. SUMEET S. CHUGH M.D. XUNZHANG WANG M.D. 《Pacing and clinical electrophysiology : PACE》2015,38(6):663-674
13.
Yuko NAKAGAWA Akiomi INOUE Norito KAWAKAMI Kanami TSUNO Kimiko TOMIOKA Mayuko NAKANISHI Kosuke MAFUNE Hisanori HIRO 《Industrial health》2014,52(6):471-479
This study investigated the cross-sectional association of job demands (i.e.,
psychological demands) and job resources (i.e., decision latitude, supervisor support,
co-worker support, and extrinsic reward) with job performance. A total of 1,198 workers
(458 males and 740 females) from a manufacturing company in Japan completed a
self-administered questionnaire that included the Job Content Questionnaire, Effort-Reward
Imbalance Questionnaire, World Health Organization Health and Work Performance
Questionnaire, and demographic survey. Hierarchical multiple regression analyses were
conducted. After adjusting for demographic characteristics, decision latitude
(β=0.107, p=0.001) and
extrinsic reward (β=0.158,
p<0.001) were positively and significantly associated
with job performance while supervisor support (β=−0.102,
p=0.002) was negatively and significantly associated
with job performance. On the other hand, psychological demands or co-worker support was
not significantly associated with job performance. These findings suggest that higher
decision latitude and extrinsic reward enhance job performance among Japanese
employees. 相似文献
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T. J. KUNICKI S. A. WILLIAMS D. R. SALOMON P. HARRISON P. CRISLER P. NAKAGAWA T. S. MONDALA S. R. HEAD D. J. NUGENT 《Journal of thrombosis and haemostasis》2009,7(12):2116-2122
Summary. Background: The Platelet Function Analyzer‐100 (PFA‐100) is widely used to measure platelet reactivity in whole blood under high shear. Objective: To characterize the genetic component of platelet reactivity among normal individuals, using the PFA‐100. Methods: We compared baseline platelet reactivity with sex, age, platelet count, hematocrit, plasma von Willebrand factor antigen (VWF:Ag), and alleles of seven candidate genes: integrin subunits α2 (ITGA2) and β3 (ITGB3), platelet glycoproteins GPIbα (GP1BA) and GPVI (GP6), purinogenic receptors (P2RY1 and P2RY12) and cyclooxygenase‐1 (COX1). Results: Based on linear and logistic regression models, we report an inverse correlation between baseline closure time (CT) initiated by collagen plus epinephrine (CEPI) and plasma VWF:Ag level, ITGA2 807T and P2RY1 893C, and an inverse correlation between baseline CT initiated by collagen plus adenosine diphosphate (CADP) and P2RY1 893C or GP1BA ‐5C. Conclusions: These results indicate that genetic polymorphisms in ITGA2 and P2RY1 combine with plasma VWF:Ag levels to modulate baseline platelet reactivity in response to collagen plus EPI, while genetic differences in P2RY1 and GP1BA significantly effect platelet responses to collagen plus ADP. Our results demonstrate that the PFA‐100 can be used to evaluate the effects of genetic predictors of platelet function. 相似文献
17.
SEIICHI KATO AKIRA OZAWA HIDENORI SHIBUYA HIROSHI NAKAGAWA HIROSHI NAGANUMA 《Pediatrics international》1993,35(1):53-56
The case of a 13 year old boy with an inflammatory esophagogastric polyp and ulcerative colitis is described. Endoscopy revealed a typical polyp and gastric fold complex at the esophagogastric junction and a hiatal hernia. Histology of a biopsy specimen confirmed an inflammatory polyp covered by hyperplastic squamous and gastric foveolar epithelium. Continuous 24 hour esophageal manometry suggested gastroesophageal reflux, which may be related to the pathogenesis of the lesion. Follow-up endoscopy showed marked regression of the polyp with medication for reflux eosphagitis. This clinical entity is rare in childhood and adolescence, and the manifestations may not be readily recognized. Therefore, endoscopic biopsy is important in children with esophageal polyps. However, polypectomy is unnecessary except when malignancy is suspected or when symptoms persist. 相似文献
18.
SEIICHI KATO NAOTAKA FUJITA HIDENORI SHIBUYA HIROSHI NAKAGAWA 《Pediatrics international》1993,35(2):151-153
In a case with chronic pancreatitis and pseudocysts related to muscular cytochrome—c oxidase deficiency, endoscopic ultrasonography (EUS) was performed to morphologically examine the pancreas for features that may have been missed by abdominal computed tomography and pancreatography. Conventional abdominal sonography had failed to show valuable diagnostic information of chronic pancreatitis in this case. EUS demonstrated several new findings. Parenchymal atrophy was remarkable, especially in the pancreatic tail, and a dilated pancreatic main or branch duct was clearly found in the region. Moreover, pancreatic stones in the main duct were also distinctly proved. EUS may become a useful new diagnostic method in pediatric gastroenterology, especially when sufficient findings are not obtained by conventional imaging techniques. However, an ultrasonographic endoscope with a shorter rigid portion and smaller caliber should be developed for pediatric patients. 相似文献
19.
KATSUYA YAMAMOTO MASARU TAKAYANAGI YASUSHI YOSHIHARA YUJI MURATA SEIICHI KATO MASATOSHI OTAKE HIROSHI NAKAGAWA 《Pediatrics international》1996,38(1):46-51
An 8 year old girl with acute disseminated encephalomyelitis (ADEM) is described. Elevated serum antibody titers suggested recent Mycoplasma pneumoniae infection. T2-weighted image of magnetic resonance imaging (MRI) disclosed multiple lesions of high signal intensity in bilateral basal ganglia and thalami as well as in the white matter. Postcontrast T1-weighted image revealed an enhanced lesion in the deep white matter. She showed rapid clinical improvement in response to corticosteroid therapy. The lesions had disappeared completely on MRI performed 10 weeks after the onset. ADEM is believed to be a demyelinating disorder of probable autoimmune etiology. MRI findings in this case may support the hypothesis that the primary pathological event is vascular injury and demyelination occurs only as a secondary phenomenon. 相似文献
20.
YOSHITSUGU KAKU SATOSHI HISANO SATOMI KANEMITSU KAORU NOHARA KEN HATAE KOHJI UEDA 《Pediatrics international》1996,38(5):476-482
The usefulness of the peritoneal equilibration test (PET) in children is unknown. The relationship between transcapillary ultrafiltration and PET was investigated in order to evaluate the usefulness of PET in children. PET was performed on 14 patients undergoing peritoneal dialysis. Their age and bodyweight ranged from 3.8 to 23.6 years and 10.2 to 55.8 kg, respectively. The patients were divided into two groups according to bodyweight; group A patients weighed ≤ 40 kg (n = 7) and group B patients weighed > 40 kg (n = 7). There was no significant difference in the mean infusion volume per bodyweight between the two groups, but the mean infusion volume per body surface area was smaller in group A than in group B. Group A showed a more rapid equilibration of dialysate glucose and creatinine than group B. Higher normalized mass transfer area coefficients were evident in group A. In spite of the lower effective glucose gradient in group A, the transcapillary ultrafiltration capacity (TUFC) showed no difference between the two groups. When the slope indices of the regression equations between the two groups were compared, the slopes of the regression in the relationship between TUFC and dialysate (D) ratios D/D0 glucose or D/P creatinine in group A were steeper than those in group B. Results of the present study indicate that the larger peritoneal area to infusion volume in patients with smaller body size results in both a rapid equilibration of solutes and sufficient transcapillary ultrafiltration. 相似文献