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11.
MASAAKI MORIOKA KEIGO KINUGAWA SADAMI FUNABIKI TADAKAZU MATSUDA YOJI FURUKAWA YOJI WANI 《International journal of urology》2006,13(9):1240-1242
A case of monotypic variant of epithelioid angiomyolipoma (AML) observed in a 62-year old woman is reported. The patient complained of abdominal fullness caused by a huge left renal mass without evidence of tuberous sclerosis complex. Imaging studies showed a left renal mass with an area showing hemorrhage and necrosis. The left renal mass, spleen and pancreatic tail were removed en bloc transabdominally. The resected tumor weighed 1200 g and showed focal necrosis and hemorrhage. Microscopically, the tumor was composed exclusively of atypical polygonal cells with copious eosinophilic cytoplasm, pleomorphic nuclei and prominent nucleoli. Tumor cells were considered to derive from perivascular epithelioid cells, and exhibited strong positive staining for HMB-45 and c-KIT, but were negative for epithelial, smooth muscle, and neural markers. As this tumor had none of the typical elements of classic AML, the final pathological diagnosis was monotypic epithelioid AML. 相似文献
12.
TAKEJI UNO YUKIO HARADA TAIZO KIMURA YOSHIAKI MOCHIDA KEIGO GOTO KAORU MIYATANI SEIICHI KUBO XIAO RANG LI 《Pediatrics international》1994,36(3):268-271
The causes of melena or hematochezia in 48 pediatric patients were examined. Malrotation with volvulus was an important cause of hemorrhage during the newborn period, and intussusception was very typical in patients aged from 1 month to 1 year. Polyps of the rectum and colon were the most common causes of melena or hematochezia in patients older than 1 year. No cause of melena or hematochezia could be identified in 11 children. Ten patients have remained in good health with no further episodes of melena or hematochezia. Localized multiple polyps of the rectum with focal carcinoma were detected in only one patient. In general, although no further investigation is required after detection of the cause of bleeding and its successful treatment, it should be kept in mind that gastrointestinal malignancy can occur in children. 相似文献
13.
Peptide Hormone Production in Small Cell Lung Carcinomas with Particular Reference to Gastrin-Releasing Peptide 总被引:4,自引:0,他引:4
YAMAGUCHI KEN; ABE KAORU; ADACHI ISAMU; OTSUBO KOTOMI; NAGASAKI KOICHI; SUZUKI MASAFUMI; MARUNO KANAME; ASANUMA FUMIKI; TSUCHIHASHI TAKAYUKI; MIYAKE YOSHIO; YOSHINAGA KEIGO; MATSUBARA HIDEKI; IMANISHI KOICHI; KIMURA SATOSHI; KODAMA TETSURO; KAMEYA TORU; SHIMOSATO YUKIO 《Japanese journal of clinical oncology》1986,16(3):235-241
Tissues of 50 small cell lung carcinomas were examined for productionof 17 peptide hormones. Only when the concentration of a peptidedetected in the tumor was 10 pmol or more per g wet weight,was the peptide considered to be produced by the tumor. Thefrequency of production of at least one of these peptide hormoneswas 84%, and that of two or more hormones was 50%. These resultsindicate that peptide hormone production is a very common phenomenonin small cell lung carcinoma. Of the peptide hormones examined,gastrin-re leasing peptide is produced with the highest frequency,suggesting that this pep- tide could play an important rolein small cell lung carcinoma. 相似文献
14.
KANETSU OKURA KATSUNORI KAMIMURA KEIGO HAMAHATA MIDORI IIJIMA MOMOKO YOSHIMOTO TORU YAMAKAWA MASARU YAMAKAWA SHIGEKAZU KUROKI IKUO KIRIYAMA TSUNEKAZU HARUTA TAKASHI FUKAYA NOBUKO YOSHIOKA YASUHIKO TOMITA TSUTOMU TSUTSUI MIEKO YOSHIOKA TOSHIKAZU NISHIO AKIYOSHI NISHIMURA YASUHIRO UENO 《Pediatrics international》1995,37(6):717-725
15.
SHIMIZU EIJI; SAIJO NAGAHIRO; EGUCHI KENJI; SHINKAI TETSU; TOMINAGA KEIGO; SASAKI YASUTSUNA; FUJITA JIRO; NOMORI HIROAKI; HOSHI AKIO 《Japanese journal of clinical oncology》1984,14(4):679-683
A phase II trial of 5'-deoxy-5-fluorouridine (5'-DFUR), a newfluorinated pyrimidine analog which has been demonstrated tohave potential superiority over 5-FU and tegafur for chemotherapyof murine tumors, was performed in patients with advanced non-smallcell carcinoma of the lung and metastatic pulmonary tumors.5'-DFUR at a dose of 800 mg/m2 was given per os every day formore than four weeks. None of 15 evaluable patients with non-smallcell carcinoma of the lung and 15 evaluable patients with metastaticpulmonary tumors showed a complete or partial response. Toxiceffects of 5'-DFUR included anorexia (29%), diarrhea (26%),nausea (23%), vomiting (10%), leukocytopenia (10%), generalfatigue (10%), liver disorder (6%) and thrombocytopenia (6%).
**Present address: Third Department of Internal Medicine, Schoolof Medicine, Toku-shima University, Kuramoto-cho 3-chome, Tokushima770, Japan. 相似文献
16.
SHIMABUKURO ZENTETSU; SAIJO NAGAHIRO; TOMINAGA KEIGO; SHINKAI TETSU; EGUCHI KENJI; SHIMIZU EIJI; SHIBUYA MASAHIKO; HOSHI AKIO 《Japanese journal of clinical oncology》1982,12(2):239-243
A phase II study of 1-(2-chloroethyl)-3-(methyl--D-glucopyranos-6-yl)-1-nitrosourea(MCNU) was conducted with 16 patients with primary lung canceror metastatic pulmonary tumors who had failed to respond toconventional therapy. MCNU was administered by a single intravenousinjection at a dose of 120 mg/m2. There were no patients whoshowed any objective responses. Although stabilization was achievedin 12 patients, four patients with primary lung cancer experiencedprogressive disease. Gastrointestinal toxicities such as anorexia,nausea and vomiting were mild or moderate and readily subsidedwithout any treatment. The major toxic side effects were leukocytopeniaand thrombocytopenia. Five patients (38.4%) had leukocytopeniaof less than 2,000/mm3 and six patients (46.1%) had thrombocytopeniaof less than 5.0x104/mm3. 相似文献
17.
YOSHIKAZU YONEI KEIGO SHIBAGAKI NOBUHIRO TSUKADA NAOKO NAGASU YASUTAKA INAGAKI KEI MIYAMOTO OSAMU SUZUKI YASUYOSHI KIRYU 《Journal of gastroenterology and hepatology》1997,12(7):495-499
The case report of a 53-year-old woman with abdominal pain and bloody diarrhoea is described. Prior to the onset of symptoms the patient had taken royal jelly for 25 days. Colonoscopy revealed that the mucosa was haemorrhagic and oedematous throughout the 20 cm long sigmoid colon. Histopathologically, mucosal haemorrhage, oedema, and infiltration of inflammatory cells were observed. Transmission electron microscopic examination revealed platelet aggregation in 30% of capillaries in the mucosal lesions. The drug-induced lymphocyte stimulation test was slightly positive for royal jelly (847 c.p.m., SI= 147%) compared with the control (576 c.p.m.). The patient's signs and symptoms disappeared within a few days after the initiation of conservative therapy, and the colonic lesions disappeared after 2 weeks of this therapy. This is the first reported case of haemorrhagic colitis associated with royal jelly intake. 相似文献
18.
YASUHIRO KATO M.D. KUNIHIKO SUZUKI M.D. MIKIO KUMAGAI M.D. KEIGO NISHIMURA M.D. HIROTOSHI MIYAMORI M.D. KENICHl KOBAYASHI M.D. NOBU HATTORI M.D. YASUJI NAKANUMA M.D. † 《The American journal of gastroenterology》1981,75(3):188-191
A 53-year old male and his daughter (38 years old) had primary biliary cirrhosis. The daughter had a high titer of antimitochondrial and other autoantibodies. Nine members, including, four living sibs, mother and two of the daughter's healthy offspring have been examined for liver function, the presence of autoimmune antibodies, cell mediated immunity and histocompatibility antigens. The eldest and second sons, mother and sisters of the affected daughter had multiple autoimmune reactions including antismooth-muscle antibodies and decreased peripheral T lymphocyte but liver tests were normal except in the eldest son. Histocompatibility antigens HL-A9 and HL-B5 were present in both patients and the elder son.
Thus the findings suggest a similar genetic predisposition to immunologic abnormalities among the family members of the patients with primary biliary cirrhosis. 相似文献
Thus the findings suggest a similar genetic predisposition to immunologic abnormalities among the family members of the patients with primary biliary cirrhosis. 相似文献