全文获取类型
收费全文 | 8371篇 |
免费 | 637篇 |
国内免费 | 31篇 |
专业分类
耳鼻咽喉 | 111篇 |
儿科学 | 193篇 |
妇产科学 | 223篇 |
基础医学 | 1314篇 |
口腔科学 | 141篇 |
临床医学 | 758篇 |
内科学 | 1865篇 |
皮肤病学 | 111篇 |
神经病学 | 799篇 |
特种医学 | 260篇 |
外科学 | 1188篇 |
综合类 | 111篇 |
现状与发展 | 1篇 |
一般理论 | 14篇 |
预防医学 | 699篇 |
眼科学 | 228篇 |
药学 | 469篇 |
中国医学 | 8篇 |
肿瘤学 | 546篇 |
出版年
2023年 | 95篇 |
2022年 | 179篇 |
2021年 | 292篇 |
2020年 | 170篇 |
2019年 | 293篇 |
2018年 | 303篇 |
2017年 | 185篇 |
2016年 | 198篇 |
2015年 | 245篇 |
2014年 | 302篇 |
2013年 | 426篇 |
2012年 | 549篇 |
2011年 | 608篇 |
2010年 | 281篇 |
2009年 | 299篇 |
2008年 | 460篇 |
2007年 | 525篇 |
2006年 | 435篇 |
2005年 | 455篇 |
2004年 | 472篇 |
2003年 | 418篇 |
2002年 | 405篇 |
2001年 | 73篇 |
2000年 | 59篇 |
1999年 | 69篇 |
1998年 | 78篇 |
1997年 | 70篇 |
1996年 | 56篇 |
1995年 | 60篇 |
1994年 | 55篇 |
1993年 | 52篇 |
1992年 | 40篇 |
1991年 | 35篇 |
1990年 | 35篇 |
1989年 | 46篇 |
1988年 | 40篇 |
1987年 | 48篇 |
1986年 | 30篇 |
1985年 | 28篇 |
1984年 | 37篇 |
1983年 | 34篇 |
1982年 | 33篇 |
1981年 | 29篇 |
1980年 | 24篇 |
1978年 | 25篇 |
1977年 | 25篇 |
1976年 | 28篇 |
1974年 | 26篇 |
1973年 | 29篇 |
1971年 | 23篇 |
排序方式: 共有9039条查询结果,搜索用时 0 毫秒
111.
Integrated major haemorrhage management in the retrieval setting: Damage control resuscitation from referral to receiving facility 下载免费PDF全文
Julian D Wijesuriya MBBS DipIMC MAcadMEd FRCA FFICM Sean Keogh FRCS FRCP FIMC FRCEM FACEM 《Emergency medicine Australasia : EMA》2017,29(4):470-475
Major haemorrhage is a leading cause of death in critically ill or injured patients requiring medical retrieval and presents significant clinical and logistic challenges irrespective of patient location, primary pathophysiology or mode of transport. It is essential that all care providers involved in the retrieval patient pathway, including referring hospitals, ambulance services, retrieval teams and tertiary receiving centres, adopt a common approach to the management of this complex patient group through the use of retrieval‐specific, integrated protocols. These should incorporate the latest clinical evidence base, recognise the differences between primary and inter‐facility missions and clearly define the roles and responsibilities of the retrieval clinical coordinator. By unifying the response across services, the aim is to facilitate seamless transition of care with ongoing damage control resuscitation from point of referral, during transfer and on arrival at the receiving centre. 相似文献
112.
Real‐life experience of tolvaptan use in the treatment of severe hyponatraemia due to syndrome of inappropriate antidiuretic hormone secretion 下载免费PDF全文
113.
Colorectal endoscopic submucosal dissection: Systematic review of mid‐term clinical outcomes 下载免费PDF全文
Nisha Patel Kinesh Patel Hutan Ashrafian Thanos Athanasiou Ara Darzi Julian Teare 《Digestive endoscopy》2016,28(4):405-416
With a drive towards minimally invasive surgery, endoscopic submucosal dissection (ESD) is now gaining popularity. In a number of East Asian countries, ESD is now the treatment of choice for early non‐metastatic gastric cancer, but the outcomes of ESD for colorectal lesions are unclear. The present review summarizes the mid‐term outcomes of colorectal ESD including complication and recurrence rates. A systematic literature search was done in May 2014, identifying 20 publications reporting the outcomes of colorectal ESD which were included in this review. En‐bloc resection rates, complete (R0) resection rates, endoscopic clearance rates, complication and recurrences rates were analyzed. Statistical pooling was done to calculate weighted means using random effects modeling. Twenty studies reporting the outcomes of 3060 colorectal ESD procedures were reported. Overall weighted en‐bloc resection rate was 89% (95% CI: 83–94%), R0 resection rate 76% (95% CI: 69–83%), endoscopic clearance rate 94% (95% CI: 90–97%) and recurrence rate 1% (95% CI: 0.5–2%). Studies that followed up patients for over 1 year were found to have an en‐bloc resection rate of 91% (95% CI: 86–96%), R0 resection rate of 81% (95% CI: 75–88%), endoscopic clearance rate 93% (95% CI: 90–97%) and recurrence rate of 0.8% (95% CI: 0.4–1%). Colorectal ESD can be carried out effectively and safely with a 1% recurrence rate. Further studies with longer follow‐up periods are required to determine whether colorectal ESD is a viable alternative to conventional surgical therapy. 相似文献
114.
115.
Gillmore JD Goodman HJ Lachmann HJ Offer M Wechalekar AD Joshi J Pepys MB Hawkins PN 《Blood》2006,107(3):1227-1229
Extensive cardiac amyloid deposition in systemic AL amyloidosis is associated with a grave prognosis. Heart transplantation is rarely performed because of the systemic and progressive nature of the disease. Patients with severe cardiac amyloid infiltration are ineligible for the preferred treatment of melphalan chemotherapy with stem cell transplantation (SCT) rescue because of the high risk for treatment-related mortality. Heart transplantation followed by SCT was performed in 5 patients with AL amyloidosis and predominant cardiomyopathy. Patients were followed up for a median of 95 months (range, 37-118 months) from diagnosis. At censor, 3 of 5 patients were well without evidence of intracardiac or extracardiac amyloid accumulation, and median overall survival by Kaplan-Meier estimate was not reached. Two patients died of progressive amyloidosis 33 and 90 months after heart transplantation after relapse of their underlying plasma cell dyscrasia. Heart transplantation followed by SCT is feasible in selected patients with cardiac AL amyloidosis and may confer substantial survival benefit. 相似文献
116.
117.
118.
119.
In the last five years, the detailedunderstanding of how to overcomeT790M drug resistance in non-small cell lung cancer (NSCLC) has culminatedin the development of a third-generation of covalent EGFR inhibitorswith excellent clinical outcomes. However, the emergence of a newlydiscovered acquired drug resistance challenges the concept of smallmolecule targeted cancer therapy in NSCLC. 相似文献
120.
Wechalekar AD Gillmore JD Wassef N Lachmann HJ Whelan C Hawkins PN 《Haematologica》2011,96(7):1079-1080