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91.
50种传统清热解毒药的抑菌实验   总被引:13,自引:1,他引:12  
华娟  周明康 《中药材》1995,18(5):255-258
本文报告了传统药物文献收载的50种清热解毒药的抑菌实验结果。显示抑菌作用的有41种,占82%。对阳性球菌显示有抑菌作用的有36种;对阴性杆菌显示有抑菌作用的有24种。其中的地胡椒、金果榄、毛果算盘子等显示有较广的抗菌效应,值得进一步研究。  相似文献   
92.
n-Hexane neuropathy was studied in 20 workers exposed for prolonged periods to this solvent, and with urinary 2, 5-hexanedione concentrations exceeding the biological exposure index recommended by the American Conference of Governmental Industrial Hygienists (5 mg/L) with a mean of 11.02 mg/L (range 5.3—24.2 mg/L). Although neurological examination did not detect significant anomalies in any of the patients, and the conduction velocity and F waves of all the nerves tested were normal, neurographic studies revealed significant differences in the amplitude of sensory nerve action potentials (SNAP) recorded from the sural (mean 14.0 μV), median (mean 17.3 μV), and ulnar (mean 7.9 μV) nerves when compared with normal values from healthy adults of the same age range, examined under identical conditions. The amplitude of the SNAP in sural and median nerves correlated significantly with the number of years worked. The notable decrease in mean amplitude of the SNAP appeared to reflect the primary neurotoxic effects of 2,5-hexanedione. © 1994 John Wiley & Sons, Inc.  相似文献   
93.
Hyperoxaluria is frequently seen in patients with inflammatory bowel disease, or after resection of the ileum. It is assumed to be responsible for the development of nephrolithiasis, nephrocalcinosis (oxalate nephrosis) and progressive renal impairment in these patients. Steatorrhea may aggravate the severity of hyperoxaluria. A 60-year-old male underwent massive resection of the jejunum and ileum 10 years prior to admission, due to strangulation of the small bowel, with occlusion of the superior mesenteric artery. He remained well except for steatorrhea which developed two-and-a-half years prior to admission, when microhematuria, proteinuria and oxaluria developed progressively. Since that time, the nephrolithiasis, nephrocalcinosis and renal failure have continued to worsen despite therapy with oxalate restriction and oxalate-binding agents. A renal biopsy, performed late in the clinical course, showed severe changes in the renal parenchyma. The decline in renal function proved irreversible. The unusual metabolic consequences of massive resection of the small intestine and their mechanisms are discussed.  相似文献   
94.
OBJECTIVE: The primary goal of this study was to evaluate the validity of the North American-European Consensus Committee (NAECC) definition for acute respiratory distress syndrome (ARDS) in pediatric patients. A secondary aim was to evaluate the threshold value for the PaO2/FiO2 ratio, used to determine which pediatric patients have ARDS. DESIGN: Retrospective cohort study. SETTING: Pediatric intensive care unit. PATIENTS: Pediatric intensive care unit patients who required mechanical ventilation, died, and underwent autopsy between January 1, 1996, and December 31, 2002 (n = 34). INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: Clinical and chest radiograph information was collected retrospectively through chart review using a standardized data collection tool. Data included the criteria specified in the NAECC definition of ARDS and demographic information. We calculated the sensitivity, specificity, positive predictive value, negative predictive value, and likelihood ratio of clinical diagnosis of ARDS compared with a pathologic diagnosis. The threshold value of PaO2/FiO2 was identified by plotting receiver operating characteristics curves and comparing the areas under the curves. The NAECC definition yielded a sensitivity of 80.7% (95% confidence interval 60-92%), specificity of 71.4% (95% confidence interval 30-95), positive predictive value of 91.3% (95% confidence interval 70-98), negative predictive value of 50.0% (95% confidence interval 20-78), and likelihood ratio of 2.82. A PaO2/FiO2 <150 had a slightly higher (but not significantly different) specificity for ARDS than a value >200 (71% vs. 86%, p = .15) without changing sensitivity. CONCLUSIONS: Our study suggests the need for further research with larger number of children to identify an optimal Pao2/Fio2 threshold for identifying ARDS in this population.  相似文献   
95.
Loss of heterozygosity for distal markers on 22q in human gliomas.   总被引:5,自引:0,他引:5  
Loss of constitutional heterozygosity as determined through the analysis of restriction-fragment-length polymorphism (RFLP) on tumoral and constitutional DNA has proven to be helpful to delimit the location of tumor-suppressor genes in the human genome. In malignant gliomas this approach indicates that chromosomes 9p, 10, 17p, and 22 may contain genes of this category involved in its origin and/or progression. Regarding chromosome 22, the data so far provided by molecular studies confirmed those previously reported by cytogenetic studies, suggesting the existence of a sub-group of malignant gliomas characterized by monosomy of this chromosome. However, the precise location of the putative glioma suppressor gene on chromosome 22 remains ambiguous. We have performed a combined cytogenetic and RFLP study on a series of 31 gliomas, looking for structural abnormalities of this chromosome. In 3 instances, terminal deletions of the long arm of chromosome 22 were observed by both methodologies, suggesting that the band q13 region distal to the D22S80 marker might be the critical domain non-randomly involved in tumor suppression of gliomas.  相似文献   
96.
用十二烷基硫酸钠或十二烷基磺酸钠与亚硫酸的混合液浸泡玉米,能有效地降低玉米淀粉中的蛋白质含量,较单独用亚硫酸浸泡,所得玉米淀粉的蛋白质含量可分别降低40%和35%。  相似文献   
97.
98.
大学生生涯规划及其对护理教育的意义   总被引:1,自引:0,他引:1  
对大学生生涯规划及国内外研究状况进行综述,指出生涯规划对护理教育的意义,提出在高等护理教育中加强大学生的生涯规划将是我国护理教育的主要发展方向之一。  相似文献   
99.
100.
羊水过少66例临床分析   总被引:1,自引:0,他引:1  
目的 分析在妊娠晚期羊水过少的早期诊断和终止妊娠方式。 方法 对海南省农垦总局医院 1990年月1日~ 2 0 0 3年 3月 66例羊水过少孕妇进行回顾性分析。 结果 妊娠 40周后羊水过少发生率及羊水污染发生率较妊娠 40周前明显增高 (P <0 0 0 1,P <0 0 5 ) ,分娩方式及新生儿预后差异无显著性 (P >0 0 5 )。 结论 妊娠达 40周后如无产兆应进行B超监测 ,及早诊断及处理羊水过少者 ,如无胎儿窘迫 ,可以阴道试产 ,必要时手术以提高围产儿出生质量。  相似文献   
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