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991.
Laura González-García Bienvenido Ros-López Bernardo Weil-Lara Sandra Pérez-da Rosa Miguel Domínguez-Páez Juan Manuel Medina-Imbroda Lorena Romero-Moreno Álvaro Martin-Gallego Miguel Ángel Arráez-Sánchez 《Neurocirugía (Asturias, Spain)》2013,24(1):47-50
Cranial fasciitis is an uncommon, rapidly-growing, benign, non-tumoural, myofibroblastic lesion of the skull, found mainly among young children in their first year of life. It is histologically similar to nodular fasciitis and pseudosarcomatous fasciitis. It may mimic more aggressive pathologies, such as sarcomatosis or histiocytosis, due to its rapid, nodular growth in subcutaneous tissue. Complete resection is considered curative and, therefore, entails a low risk of metastases or malignant recurrences.We present the clinical, radiological and pathological findings in a 4-year-old boy with cranial fasciitis in the deep, subcutaneous, soft tissue, with erosion of the outer table of the cranium, which also produced periosteal reaction, while respecting the inner table and meninges. The objective of this article is to highlight the absence of radiotherapeutic or chemotherapeutic adjuvant treatment. In addition, an exhaustive review of the literature is also presented. 相似文献
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993.
Shucheng Gu Yanjun Xv Chengming Fei Chao Xiao Juan Guo Youshan Zhao 《Hematology (Amsterdam, Netherlands)》2017,22(1):9-15
Objectives: In order to gain an insight into labile plasma iron (LPI) in iron metabolism microenvironment in MDS.Methods: We performed ELISA, quantitative real-time polymerase chain reaction, flow cytometry, MRI T2* assays to test LPI, iron biochemical parameters, and liver iron concentration (LIC) among 22 MDS patients.Results: LPI has a statistical difference (P?0.001 by analysis of variance (ANOVA)), which decreased gradually, among three groups, while no difference was found in adjusted serum ferritin (ASF) (P?=?0.086 by ANOVA). After DFO treatment, serum hepcidin expression increased from 301.26?±?59.78 to 340.33?±?49.78?µg/l (P?=?0.032), while hepcidin/ASF was upregulated gradually from 0.16?±?0.08 to 0.22?±?0.03 (P?=?0.045). APAF-1 expression (P?=?0.047) and erythroid apoptosis rate (P?=?0.009) decreased significantly, respectively. No statistical difference was found in EPO (P?=?0.247) and GDF15 expression (P?=?0.172). LIC dropped from 9.83?±?4.84 to 6.28?±?4.01?mg/g dry weight (P?0.001). No significant difference was found in cardiac T2* (P?=?0.594). LPI has a closer connection to LIC than ASF (r?=?0.739, P?0.001 vs. r?=?0.321, P?=?0.034).Discussion: LPI seems to be a real-time indicator which reflects body iron loading status instantaneously. Despite the limited knowledge available on LPI speciation in different types and degrees of IO, LPI measurements can be and are in fact used for identifying systemic IO and for initiating/adjusting chelation regimens. 相似文献
994.
A new 5(6→7)abeo-sterol, podosterol (1), together with 20 known compounds, were isolated from the leaves of Podocarpus fleuryi. Their structures were elucidated by means of extensive spectroscopic analysis. Podosterol was assessed for its cytotoxicity against five human tumor cell lines (HL-60, SMMC-7721, A-549, MCF-7, and SW-480), and the result showed that it had no activity. 相似文献
995.
Gabriel Alcalá-Cerra Ángel Paternina-Caicedo Cindy Díaz-Becerra Juan José Gutiérrez-Paternina 《Neurocirugía (Asturias, Spain)》2013,24(4):154-162
ObjectiveThe objective of our study was to determine the seizure control rate of cerebral hemispherectomies in adult patients with drug-resistant epilepsy.Materials and methodsA systematic review and individual patient data meta-analysis was carried out. Seven international databases and scientific meeting proceedings were reviewed. Individual patient data were analysed to establish potential factors associated with postoperative seizure control.ResultsEight articles that satisfied the pre-established selection criteria were identified.After a median follow-up of 70 months (interquartile range, 29-175.5), 79.4% of patients remained seizure-free. There were no statistically significant differences in age at onset of epilepsy, duration of epilepsy, age at surgery, time of follow-up, gender, surgical-laterality, aetiology and ictal EEG abnormalities between seizure-free patients and those with recurrences.ConclusionsCerebral hemispherectomy has a high seizure control rate in adult patients with drug-resistant epilepsy. None of the variables analysed in the present study were associated with surgical success. 相似文献
996.
Corentin M. Barbu Alison M. Buttenheim Maria-Luz Hancco Pumahuanca Javier E. Quintanilla Calderón Renzo Salazar Malwina Carrión Andy Catacora Rospigliossi Fernando S. Malaga Chavez Karina Oppe Alvarez Juan Cornejo del Carpio César Náquira Michael Z. Levy 《Emerging infectious diseases》2014,20(12):2055-2063
Chagas disease vector control campaigns are being conducted in Latin America, but little is known about medium-term or long-term effectiveness of these efforts, especially in urban areas. After analyzing entomologic data for 56,491 households during the treatment phase of a Triatoma infestans bug control campaign in Arequipa, Peru, during 2003–2011, we estimated that 97.1% of residual infestations are attributable to untreated households. Multivariate models for the surveillance phase of the campaign obtained during 2009–2012 confirm that nonparticipation in the initial treatment phase is a major risk factor (odds ratio [OR] 21.5, 95% CI 3.35–138). Infestation during surveillance also increased over time (OR 1.55, 95% CI 1.15–2.09 per year). In addition, we observed a negative interaction between nonparticipation and time (OR 0.73, 95% CI 0.53–0.99), suggesting that recolonization by vectors progressively dilutes risk associated with nonparticipation. Although the treatment phase was effective, recolonization in untreated households threatens the long-term success of vector control. 相似文献
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