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71.
72.
Five commercially available nitropolyclyclic aromatic hydrocarbons (nitro-PAH), namely, 4-nitrobiphenyl, 2-nitrofluorene, 9-nitroanthracene, 1-nitropyrene, and 2,7-dinitrofluorene, were exposed under restricted sunlight in the open air. The direct-acting mutagenicities of the samples after an exposure of 45 days were measured in order to compare them with those of the original samples in the Ames Salmonella typhimurium bioassay. It was found that the mutagenicities of some nitro-PAH do not change significantly while the mutagenicities of others increase or decrease after exposure. A preliminary study of nitro-PAH reaction products after exposure using GC, GC/MS, and FT-IR is also reported. 相似文献
73.
采用荧光偏振免疫法测定14例剖宫产术后应用肌注或静点庆大霉素的产妇乳汁及血清中庆大霉素的浓度,结果表明肌注或静点庆大霉素后3 ̄5小时,乳汁中浓度达峰值,血清中庆大霉素的浓度于给药后0.5小时达峰值。提示:无论肌注或静脉给庆大霉素均可经乳汁排泄,乳母不宜应用庆大霉素,即使产后已应用庆大霉素,应停药13小时后方可哺乳。 相似文献
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76.
小儿先天性髋关节脱位近年来应用术式的演变及其评估 总被引:5,自引:2,他引:3
本文介绍本院近4年来小儿先天性髋脱位治疗应用术式的演变。由20多年来一直喜欢用骨盆截骨术演变为近1年来用得最多的是造盖术。近4年共手术463例,565髋。实践证明:比起骨盆截骨术,造盖术显得更简便,侵袭小,不需二次手术拔除内固定针。因在我国大龄髋脱位偏多,造盖术更适合我国国情。经过一些改进,可以克服造盖折断和吸收问题。 相似文献
77.
补肾中药对雄激素致不孕大鼠卵巢核仁组成区蛋白的影响 总被引:4,自引:0,他引:4
观察补肾中药对雄激素致不孕大鼠卵巢核仁组成区蛋白的影响。用SD雌性大鼠幼仔,出生9d龄注射丙酸睾丸酮,制成雄激素致不孕大鼠(ASR)模型。80d龄灌服补肾中药水溶液两周。100d龄心脏灌注处死。以核仁组成区蛋白嗜银染色(AgNOR)和增殖细胞核杭原(PcNA)为指标,观察卵巢颗粒细胞、间质腺细胞的形态学变化。结果:补肾中药能够使ASR卵巢颗粒细胞增殖、卵泡发育。治疗组的AgNOR和PcNA计数明显高于模型组,而与对照组之间无显著差异。结论:补肾中药的这种作用可能是通过调节了下丘脑-垂体-卵巢性腺功能的结果,从而促使卵巢颗粒细胞发育、卵泡成熟。 相似文献
78.
膀胱移行细胞癌分级诊断的研究中三种定量分析方法的评价 总被引:1,自引:0,他引:1
应用HI-CI真彩色病理图像分析仪对86例移行细胞癌的核形态,DNA量和AgNoRs颗粒进行了定量分析。三种方法分别和综合作分级判别分析。分级结果与WHO分级结果对比并分析他们与预后的关系。结果证明,三种定量方法在膀胱癌分级诊断中都是比较客观而有价值的方法。1级癌的判别效果最好,一致率为90.9%~100%。各种方法分级与WHO一致率以形态定量法较好,为86.0%,AgNoRs为77.9%,DNA为76.7%。对预后估计的价值以AgNoRs法最好,DNA法次之。三种方法综合分级判别可稍提高分级诊断一致率,达88.4%。 相似文献
79.
Viral markers were studied in 79 cases of viral hepatitis with hepatic failure. The results were shown as follows: 8 cases were positive for anti-HAV IgM (10.12%); 76 cases positive for HBsAg or anti-HBc IgM (96.20%) and 41 cases positive for anti-HCV antibodies (51.89%). Among those with anti-HCV positive, 35 cases were co-infected with HBV, 5 cases with HAV and/or HCV, only one was infected with HCV alone 2 cases were HD-Ag positive (2.52%) and one not identified (1.27%). With the reference of clinical findings, patients co-infected with HBV/HCV or anti-HBc IgM positive were more critical and usually entail higher mortality. In cases with HCV co-infections, the positive HBV replication markers seems to be reduced. Hepatic failure without HBV replicative markers had a high rate of hepatic coma as well as poor outcome. 相似文献
80.
Effects of smoking and drinking on excretion of hippuric acid among toluene-exposed workers 总被引:1,自引:1,他引:0
Osamu Inoue Kazunori Seiji Takao Watanabe Haruo Nakatsuka Chui Jin Shi-Jie Liu Masayuki Ikeda 《International archives of occupational and environmental health》1993,64(6):425-430
Summary In order to investigate possible effects of smoking and drinking on the metabolism of toluence in occupational settings, 206 toluene-exposed men (mean age: 31.4 years) in shoemaking, painting, or surface-coating workshops together with 246 nonexposed control men (36.8 years) were studied for the time-weighted average intensities of exposure to toluene, hippuric acid concentration in shift-end urine samples, and the two social habits of smoking and drinking. The mean daily consumptions of cigarettes and ethanol were about 20 pieces and 10 g among smokers and drinkers, respectively. The geometric mean toluene concentration among the exposed subjects was about 20 ppm, with a maximum of 521 ppm. Regression analysis after classification of the subjects by smoking and drinking clearly demonstrated that the two social habits, when combined, markedly reduce the hippuric acid level in the urine of workers exposed to was a significant association between smoking and drinking habits, which hindered separate evaluation of the effects of the two habits on toluene metabolism. Comparison of the present results with the findings reported in the literature, however, suggested that the observed effects may be attributable to smoking rather than to drinking habits. 相似文献