全文获取类型
收费全文 | 186507篇 |
免费 | 1767篇 |
国内免费 | 67篇 |
专业分类
耳鼻咽喉 | 1253篇 |
儿科学 | 6821篇 |
妇产科学 | 3171篇 |
基础医学 | 17983篇 |
口腔科学 | 1835篇 |
临床医学 | 13339篇 |
内科学 | 33262篇 |
皮肤病学 | 839篇 |
神经病学 | 17732篇 |
特种医学 | 9586篇 |
外科学 | 30824篇 |
综合类 | 2351篇 |
一般理论 | 2篇 |
预防医学 | 18591篇 |
眼科学 | 3004篇 |
药学 | 10028篇 |
中国医学 | 636篇 |
肿瘤学 | 17084篇 |
出版年
2023年 | 125篇 |
2022年 | 160篇 |
2021年 | 314篇 |
2020年 | 245篇 |
2019年 | 322篇 |
2018年 | 22204篇 |
2017年 | 17644篇 |
2016年 | 19800篇 |
2015年 | 1294篇 |
2014年 | 1242篇 |
2013年 | 1401篇 |
2012年 | 7855篇 |
2011年 | 21899篇 |
2010年 | 19282篇 |
2009年 | 11964篇 |
2008年 | 20310篇 |
2007年 | 22487篇 |
2006年 | 1327篇 |
2005年 | 2865篇 |
2004年 | 3971篇 |
2003年 | 4902篇 |
2002年 | 3001篇 |
2001年 | 362篇 |
2000年 | 458篇 |
1999年 | 236篇 |
1998年 | 299篇 |
1997年 | 292篇 |
1996年 | 154篇 |
1995年 | 154篇 |
1994年 | 143篇 |
1993年 | 111篇 |
1992年 | 77篇 |
1991年 | 121篇 |
1990年 | 154篇 |
1989年 | 114篇 |
1988年 | 89篇 |
1987年 | 65篇 |
1986年 | 41篇 |
1985年 | 53篇 |
1984年 | 39篇 |
1983年 | 52篇 |
1982年 | 51篇 |
1980年 | 61篇 |
1974年 | 30篇 |
1969年 | 26篇 |
1938年 | 60篇 |
1937年 | 26篇 |
1934年 | 31篇 |
1932年 | 58篇 |
1930年 | 49篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
81.
Introduction
Planning human resources for health (HRH) is a complex process for policy-makers and, as a result, many countries worldwide swing from surplus to shortage. In-depth case studies can help appraising the challenges encountered and the solutions implemented. This paper has two objectives: to identify the key challenges in HRH planning in Belgium and to formulate recommendations for an effective HRH planning, on the basis of the Belgian case study and lessons drawn from an international benchmarking. 相似文献82.
Antonio Gómez Mercedes Salgado Manuel Valladares-Ayerbes Mónica Jorge Ana Carballo Sonia Candamio Pilar Izquierdo Paula Peleteiro Rafael López 《Clinical & translational oncology》2010,12(12):843-848
Objective
The aim of the project was to assess the effectiveness and safety of weekly epoetin-beta (EB) in patients with gastrointestinal cancer (GIC) subjected to concomitant chemoradiotherapy (CCTRT). 相似文献83.
Seppo W. Langer 《Current oncology reports》2010,12(4):242-246
Extravasation of chemotherapy is a feared complication of anticancer therapy. The accidental leakage of cytostatic agents
into the perivascular tissues may have devastating short-term and long-term consequences for patients. In recent years, the
increased focus on chemotherapy extravasation has led to the development of international guidelines that have proven useful
tools in daily clinical practice. Moreover, the tissue destruction in one of the most dreaded types of extravasation (ie,
anthracycline extravasation) now can effectively be prevented with a specific antidote, dexrazoxane. 相似文献
84.
Carlos Ferrer Albiach Antonio Conde Moreno Marta Rodríguez Cordón Virginia Morillo Macías Ana Bouché Babiloni Inmaculada Beato Tortajada Ángel Sánchez Iglesias Alicia Francés Muñoz 《Clinical & translational oncology》2010,12(1):22-26
Hypoxia is related to poor prognosis because it is associated to chemo-and radioresistance. During recent years the evolution
of imaging methods like PET/CT and MRI has meant the appearance of new perspectives with direct implications in radiation
therapy. We discuss previous experiences in staging, planning and in the follow-up process with these techniques for measuring
tumour hypoxia. 相似文献
85.
Lidong Zhang James E Littlejohn Yu Cui Xiaobo Cao Chander Peddaboina W Roy Smythe 《Molecular cancer》2010,9(1):110
Background
Bortezomib, a proteasome-specific inhibitor, has emerged as a promising cancer therapeutic agent. However, development of resistance to bortezomib may pose a challenge to effective anticancer therapy. Therefore, characterization of cellular mechanisms involved in bortezomib resistance and development of effective strategies to overcome this resistance represent important steps in the advancement of bortezomib-mediated cancer therapy. 相似文献86.
Jens O L J?rgensen Louise M?ller Morten Krag Nils Billestrup Jens S Christiansen 《Endocrinology & Metabolism Clinics of North America》2007,36(1):75-87
This article focuses on in vivo data from tests performed in normal subjects and in patients who had abnormal growth hormone (GH) status. Experimental data in human subjects demonstrate that GH acutely inhibits glucose disposal in skeletal muscle. At the same time GH stimulates the turnover and oxidation of free fatty acid (FFA), and experimental evidence suggests a causal link between elevated FFA levels and insulin resistance in skeletal muscle. Observational data in GH-deficient adults do not indicate that GH replacement is associated with significant impairment of glucose tolerance, but it is recommended that overdosing be avoided and glycemic control be monitored. 相似文献
87.
Background
The fibromyalgia syndrome (FMS) is suggested to be a manifestation of depression or affective spectrum disorder. We measured the cognitive style of patients with FMS to assess personality styles in 44 patients with fibromyalgia syndrome (FMS) by comparing them with 43 patients with major depressive disorder (MDD) and 41 healthy controls (HC). 相似文献88.
89.
90.
Kimberly A. Varker Edward W. Martin Dori Klemanski Bryan Palmer Manisha H. Shah Mark Bloomston 《Journal of gastrointestinal surgery》2007,11(12):1680-1685
Background
Transarterial chemoemobolization (TACE) is commonly used to treat metastatic carcinoid tumors; however, the management of
progressive disease is less clear. We sought to determine if patients with disease progression after TACE would benefit from
repeat TACE.
Methods
The records of 27 patients undergoing repeat TACE for radiologic or symptomatic progression after TACE for metastatic carcinoid
were reviewed and compared to 122 undergoing first TACE. Overall and progression-free survivals were estimated by the Kaplan–Meier
method.
Results
Mean disease-free interval after first TACE was 11.8 months. Radiologic response was observed in 61% compared to 82% after
first TACE (p = 0.058); hormone response in 64% compared to 80% (p = 0.159); and symptomatic response in 77% compared to 92% (p = 0.053). The complication rate after repeat TACE was lower than after first TACE (p = 0.03). Median overall survival was similar after repeat (28.1 months) and first TACE (33.3 months) (p = 0.53). Progression-free survival was shorter after repeat TACE but not significantly so. No factor examined could predict
survival after repeat TACE.
Conclusion
Repeat TACE for patients with hepatic carcinoid metastases failing first TACE or having evidence of disease progression is
safe and offers a viable treatment option.
Presented at the 48th Annual Meeting of The Society for Surgery of the Alimentary Tract, Washington, DC, May, 2007. 相似文献