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排序方式: 共有10000条查询结果,搜索用时 15 毫秒
981.
982.
Primary care nursing activities with patients affected by physical chronic disease and common mental disorders: a qualitative descriptive study 下载免费PDF全文
983.
984.
985.
Assessment of myocardial partition coefficient of gadolinium (λ) in dilated cardiomyopathy and its impact on segmental and global systolic function 下载免费PDF全文
Alexis Jacquier MD PhD Alexandros Kallifatidis MD Nicolas Guibert MD Roch Giorgi MD PhD Claire Falque MD Franck Thuny MD PhD Pierre Croisille MD PhD Patrick Clarysse PhD Boris Maurel MD Antonin Flavian MD Jean‐Yves Gaubert MD Guy Moulin MD Gilbert Habib MD 《Journal of magnetic resonance imaging : JMRI》2014,40(6):1336-1341
986.
Client and clinical staff perceptions of barriers to and enablers of the uptake and delivery of behavioural interventions for urinary incontinence: qualitative evidence synthesis 下载免费PDF全文
Beverley French PhD RN Lois H. Thomas BA PhD RN Joanna Harrison BA MA Jacqueline Coupe BSc MPH MBPsS Brenda Roe PhD RN RHV Joanne Booth BSc BA PhD RN Francine M. Cheater BA PhD RN Michael J. Leathley BA PhD PGDip Caroline L. Watkins BA PhD RN Jean Hay‐Smith PhD MSc DipPhysiotherapy MPNZ the ICONS Project Team the ICONS Patient Public Carer Groups 《Journal of advanced nursing》2017,73(1):21-38
987.
A new tool to test active ingredient using lactic acid in vitro,a help to understand cellular mechanism involved in stinging test: An example using a bacterial polysaccharide (Fucogel®) 下载免费PDF全文
Mehdi Sakka Raphael Leschiera Christelle Le Gall‐Ianotto Olivier Gouin Killian L'herondelle Paul Buscaglia Olivier Mignen Jean‐Luc Philbé Thibaut Saguet Jean‐Luc Carré Laurent Misery Nicolas Lebonvallet 《Experimental dermatology》2018,27(3):238-244
The stinging test is an in vivo protocol that evaluates sensitive skin using lactic acid (LA). A soothing sensation of cosmetics or ingredients can be also appreciated through a decrease in stinging score. To predict the soothing sensation of a product before in vivo testing, we developed a model based on an LA test and substance P (SP) release using a co‐culture of human keratinocytes and NGF‐differentiated PC12 cells. A bacterial fucose‐rich polysaccharide present in Fucogel® was evaluated as the soothing molecule in the in vivo stinging test and our in vitro model. Excluding toxic concentrations, the release of SP was significant from 0.2% of lactic acid for the PC12 cells and from 0.1% of lactic acid for the keratinocytes. When the pH was adjusted to approximately 7.4, LA did not provoke SP release. At these concentrations of LA, 0.1% of polysaccharide showed a significant decrease in SP release from the two cellular types and in co‐cultures without modifying the pH of the medium. In vivo, a stinging test using the polysaccharide showed a 30% decrease in prickling intensity vs the placebo in 19 women between the ages of 21 and 69. Our in vitro model is ethically interesting and is adapted for cosmetic ingredients screening because it does not use animal experimentation and limits human volunteers. Moreover, Fucogel® reduced prickling sensation as revealed by the in vivo stinging test and inhibits the neurogenic inflammation as showed by our new in vitro stinging test based on SP release. 相似文献
988.
989.
Neonatal BCG has no effect on allergic sensitization and suspected food allergy until 13 months 下载免费PDF全文
Lisbeth Marianne Thøstesen Henrik Fomsgaard Kjaer Gitte Thybo Pihl Thomas Nørrelykke Nissen Nina Marie Birk Jesper Kjærgaard Aksel Karl Georg Jensen Peter Aaby Annette Wind Olesen Lone Graff Stensballe Dorthe Lisbeth Jeppesen Christine Stabell Benn Poul‐Erik Kofoed 《Pediatric allergy and immunology》2017,28(6):588-596
990.
Jacques Lalevée Guillaume Povie Mohamad Ali Tehfe Sofia Telitel Fabrice Morlet‐Savary Bernadette Graff Jean Pierre Fouassier 《Macromolecular chemistry and physics.》2012,213(15):1618-1622
Upon demand, 1,3‐diamino‐propane‐triethylborane (DAPTB) is photolyzed in the presence of an acid generator such as a diphenyliodonium salt. Interestingly, triethylborane is released. In the presence of oxygen, ethyl radicals are generated and initiate an acrylate polymerization. This is the first example of a phototriggered production of a triethylborane usable in the photoinitiation of acrylate polymerizations. This approach is also worthwhile to overcome the oxygen inhibition for free‐radical polymerization processes. 相似文献