全文获取类型
收费全文 | 592篇 |
免费 | 27篇 |
国内免费 | 5篇 |
专业分类
耳鼻咽喉 | 3篇 |
儿科学 | 33篇 |
妇产科学 | 7篇 |
基础医学 | 64篇 |
口腔科学 | 17篇 |
临床医学 | 86篇 |
内科学 | 121篇 |
皮肤病学 | 36篇 |
神经病学 | 13篇 |
特种医学 | 131篇 |
外科学 | 21篇 |
综合类 | 22篇 |
预防医学 | 26篇 |
眼科学 | 4篇 |
药学 | 15篇 |
1篇 | |
肿瘤学 | 24篇 |
出版年
2023年 | 1篇 |
2022年 | 4篇 |
2021年 | 2篇 |
2020年 | 3篇 |
2019年 | 5篇 |
2018年 | 9篇 |
2017年 | 4篇 |
2016年 | 10篇 |
2015年 | 10篇 |
2014年 | 11篇 |
2013年 | 17篇 |
2012年 | 7篇 |
2011年 | 11篇 |
2010年 | 27篇 |
2009年 | 29篇 |
2008年 | 14篇 |
2007年 | 23篇 |
2006年 | 17篇 |
2005年 | 16篇 |
2004年 | 10篇 |
2003年 | 4篇 |
2002年 | 13篇 |
2001年 | 8篇 |
2000年 | 5篇 |
1999年 | 10篇 |
1998年 | 37篇 |
1997年 | 45篇 |
1996年 | 38篇 |
1995年 | 19篇 |
1994年 | 29篇 |
1993年 | 22篇 |
1992年 | 9篇 |
1991年 | 10篇 |
1990年 | 11篇 |
1989年 | 22篇 |
1988年 | 20篇 |
1987年 | 10篇 |
1986年 | 8篇 |
1985年 | 5篇 |
1984年 | 14篇 |
1983年 | 14篇 |
1982年 | 12篇 |
1981年 | 11篇 |
1980年 | 7篇 |
1979年 | 1篇 |
1978年 | 3篇 |
1977年 | 2篇 |
1976年 | 4篇 |
1969年 | 1篇 |
排序方式: 共有624条查询结果,搜索用时 15 毫秒
101.
Protective effects of polydatin against CCl4-induced injury to primarily cultured rat hepatocytes 总被引:5,自引:0,他引:5
HUANG Zhao Sheng WANG Zong Wei LIU Ming Ping ZHONG Shi Qing LI Qiao Mei RONG Xiang Lu 《World journal of gastroenterology : WJG》1999,(1):41-44
NTRODUCTIONPolygonumcuspidatumSieb.etZucc.(Polygonaceae)isatraditionalChineseherbaldrug,withbitertasteandcoldnature.Itmainly... 相似文献
102.
Abdominal trauma: use of oral contrast material for CT is safe 总被引:2,自引:0,他引:2
103.
104.
MP Costi D Tondi M Rinaldi D Barlocco G Cignarella DV Santi C Musiu I Pudu G Vacca P La Colla 《European journal of medicinal chemistry》1996,31(12):1011-1016
A new series of N-(substituted)benzyl-1,8-naphthalimides 4, structurally related to the previously reported thymidylate synthase (TS) inhibitor naphthaleins 3, were synthesized and compounds tested for their inhibition of several species of TS. Moreover, their in vitro cytotoxicity together with antimycotic and antibacterial properties were assayed. While no activity was detected in the antibacterial tests, the m-nitro (4ae) and the p-nitro (4af) derivatives were found able to partially inhibit TS at low micromolar concentrations. Introduction of nitro or (substituted)-amino groups in position 4 of the naphthalic ring always led to less active compounds. 相似文献
105.
R?FoyEmail author MP?Eccles G?Jamtvedt J?Young JM?Grimshaw R?Baker 《BMC health services research》2005,5(1):50
Background
Improving the quality of health care requires a range of evidence-based activities. Audit and feedback is commonly used as a quality improvement tool in the UK National Health Service [NHS]. We set out to assess whether current guidance and systematic review evidence can sufficiently inform practical decisions about how to use audit and feedback to improve quality of care. 相似文献106.
107.
S Saravanan C Kalyani MP Vijayarani P Jayakodi AJW Felix S Nagarajan P Arunmozhi V Krishnan 《Indian Journal of Community Medicine》2008,33(3):146-150
Background:
Fluorosis is one of the common but major emerging areas of research in the tropics. It is considered endemic in 17 states of India. However, the Cuddalore district of Tamil Nadu is categorised as a fluorosis non-endemic area. But clinical cases of dental fluorosis were reported in the field practice area of Department of Community Medicine, Rajah Muthiah Medical College, Annamalai University, Chidambaram. Since dental fluorosis has been described as a biomarker of exposure to fluoride, we assessed the prevalence and severity of dental fluorosis among primary school children in the service area.Materials and Methods:
Children studying in six primary schools of six villages in the field practice area of Rural Health Centre of Faculty of Medicine, Annamalai University, Chidambaram, were surveyed. Every child was clinically examined at the school by calibrated examiners with Dean''s fluorosis index recommended by WHO (1997). Chi-square test, Chi-square trend test and Spearman''s rank correlation coefficient test were used for statistical analysis.Results:
Five hundred and twenty-five 5- to 12-year-old school children (255 boys and 270 girls) were surveyed. The overall dental fluorosis prevalence was found to be 31.4% in our study sample. Dental fluorosis increased with age P < 0.001, whereas gender difference was not statistically significant. Aesthetically objectionable dental fluorosis was found in 2.1% of the sample. Villages Senjicherry, Keezhaperambai and Kanagarapattu revealed a community fluorosis index (CFI) score of 0.43, 0.54 and 0.54 with 5.6%, 4.8% and 1.4% of objectionable dental fluorosis, respectively. Correlation between water fluoride content and CFI values in four villages was noted to be positively significant.Conclusion:
Three out of six villages studied were in ‘borderline’ public health significance (CFI score 0.4-0.6). A well-designed epidemiological investigation can be undertaken to evaluate the risk factors associated with the condition in the study region. 相似文献108.
Azadeh Ebrahimi-Madiseh Robert H. Eikelboom Dona MP. Jayakody Marcus D. Atlas 《Cochlear implants international》2013,14(2):75-80
Objectives: To evaluate the clinical utility of the City University of New York sentence test in a cohort of post-lingually deafened cochlear implants recipients over time.Methods: 117 post-lingually deafened, Australian English-speaking CI recipients aged between 23 and 98 years (M?=?66 years; SD?=?15.09) were recruited. CUNY sentence test scores in quiet were collated and analysed at two cut-offs, 95% and 100%, as ceiling scores.Results: CUNY sentence scores ranged from 4% to 100% (M?=?86.75; SD?=?20.65), with 38.8% of participants scoring 95% and 16.5% of participants reaching the 100% scores. The percentage of participants reaching the 95% and 100% ceiling scores increased over time (6 and 12 months post-implantation).The distribution of all post-operative CUNY test scores skewed to the right with 82% of test scores reaching above 90%.Discussion: This study demonstrates that the CUNY test cannot be used as a valid tool to measure the speech perception skills of post-lingually deafened CI recipients over time. This may be overcome by using adaptive test protocols or linguistically, cognitively or contextually demanding test materials.Conclusion: The high percentage of CI recipients achieving ceiling scores for the CUNY sentence test in quiet at 3 months post-implantation, questions the validity of using CUNY in CI assessment test battery and limits its application for use in longitudinal studies evaluating CI outcomes. Further studies are required to examine different methods to overcome this problem. 相似文献
109.
110.
Microbiological culture analysis of the tongue anaerobic microflora in subjects with and without halitosis 总被引:1,自引:0,他引:1
AC Donaldson D McKenzie MP Riggio PJ Hodge H Rolph A Flanagan J Bagg 《Oral diseases》2005,11(S1):61-63
Objective: Determination of the microflora present on the tongue dorsum of subjects with and without halitosis using conventional microbiological culture methods.
Methods: Twenty-one halitosis and 20 control patients were recruited using a strict clinical protocol. Samples were collected from the posterior dorsum of the tongue using a sterile brush. Each sample was vortex mixed for 30 s and serial 10-fold dilutions to 10−7 were carried out. Samples were plated onto fastidious anaerobe agar (FAA) and FAA enriched with vancomycin. These were incubated under anaerobic conditions for 10 days at 37°C. Strict anaerobes were identified by metronidazole sensitivity and bacteria were identified to genus level by a combination of colony morphology, Gram staining and biochemical and enzymatic tests (rapid ID 32 A).
Results: The predominant species in test and control groups were Veillonella sp. and Prevotella sp. Greater species diversity was found in the halitosis samples compared with controls. The halitosis samples contained an increased incidence of unidentifiable Gram-negative rods, Gram-positive rods and Gram-negative coccobacilli.
Conclusions: There was no obvious association between halitosis and any specific bacterial genus. The increased species diversity found in halitosis samples suggests that halitosis may be the result of complex interactions between several bacterial species. The role of uncultivable bacteria may also be important in contributing to this process. 相似文献
Methods: Twenty-one halitosis and 20 control patients were recruited using a strict clinical protocol. Samples were collected from the posterior dorsum of the tongue using a sterile brush. Each sample was vortex mixed for 30 s and serial 10-fold dilutions to 10
Results: The predominant species in test and control groups were Veillonella sp. and Prevotella sp. Greater species diversity was found in the halitosis samples compared with controls. The halitosis samples contained an increased incidence of unidentifiable Gram-negative rods, Gram-positive rods and Gram-negative coccobacilli.
Conclusions: There was no obvious association between halitosis and any specific bacterial genus. The increased species diversity found in halitosis samples suggests that halitosis may be the result of complex interactions between several bacterial species. The role of uncultivable bacteria may also be important in contributing to this process. 相似文献